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Tytuł pozycji:

Naming HLA diversity: A review of HLA nomenclature.

Tytuł:
Naming HLA diversity: A review of HLA nomenclature.
Autorzy:
Hurley CK; Georgetown University, Washington, DC, USA. Electronic address: .
Źródło:
Human immunology [Hum Immunol] 2021 Jul; Vol. 82 (7), pp. 457-465. Date of Electronic Publication: 2020 May 08.
Typ publikacji:
Journal Article; Review
Język:
English
Imprint Name(s):
Original Publication: [New York] Elsevier/North-Holland.
MeSH Terms:
Alleles*
Genetic Variation*
HLA Antigens/*classification
HLA Antigens/*genetics
Epitopes ; Genotype ; HLA Antigens/immunology ; Histocompatibility Testing ; Humans ; Polymorphism, Genetic ; Serologic Tests ; Terminology as Topic
Contributed Indexing:
Keywords: Human leukocyte antigens; Nomenclature; Polymorphism
Substance Nomenclature:
0 (Epitopes)
0 (HLA Antigens)
Entry Date(s):
Date Created: 20200421 Date Completed: 20220104 Latest Revision: 20220104
Update Code:
20240104
DOI:
10.1016/j.humimm.2020.03.005
PMID:
32307125
Czasopismo naukowe
The development of a standardized HLA nomenclature has been critical in our understanding of the HLA system and in facilitating the clinical applications of HLA. The Nomenclature Committee for Factors of the HLA System, established in 1968, has overseen the development and usage of nomenclature based on serologic specificities, cellular responses, and DNA sequences. Their decisions have been guided by community consensus reached through 17 international workshops beginning in 1964 and continuing today. Two websites provide a curated database of the sequences of over 26,000 HLA alleles and a reference site for the current nomenclature. This review covers the major steps in the development of the HLA nomenclature as well as the efforts of other groups to extend its usefulness for research and clinical applications.
Competing Interests: Conflict of interest Georgetown University has filed a patent application on which author Hurley is an inventor of the HLA typing and Sanger-based sequencing technology.
(Copyright © 2020 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.)

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