[The "Historic Study" SOLIDARITY-Research's Answer to the Sars-CoV-2 Pandemic].

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Abstrakt

Tytuł:: [The "Historic Study" SOLIDARITY-Research's Answer to the Sars-CoV-2 Pandemic].
Autorzy:: Gadebusch Bondio M; Institute for Medical Humanities, UKB University Hospital Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Deutschland. .
Marloth M; University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Psychiatry, Germany, University of Cologne, Köln, Deutschland.
Transliterated Title:: Die „historische Studie“ SOLIDARITY als Antwort der Forschung auf die Sars-CoV-2 Pandemie.
Źródło:: NTM [NTM] 2020 Jun; Vol. 28 (2), pp. 219-225.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
Język:: German
Imprint Name(s):: Publication: 1993- : Cham, Switzerland : Springer International Publishing
Original Publication: Leipzig : Akademische Verlagsgesellschaft Geest & Portig
MeSH Terms:: Betacoronavirus*
Clinical Trials as Topic*/ethics
Clinical Trials as Topic*/organization & administration
Pandemics*
Antiviral Agents/*therapeutic use
Coronavirus Infections/*drug therapy
Coronavirus Infections/*epidemiology
Pneumonia, Viral/*drug therapy
Pneumonia, Viral/*epidemiology
Adenosine Monophosphate/analogs & derivatives ; Adenosine Monophosphate/therapeutic use ; Alanine/analogs & derivatives ; Alanine/therapeutic use ; Bioethical Issues ; COVID-19 ; Chloroquine/therapeutic use ; Drug Combinations ; Editorial Policies ; Humans ; Hydroxychloroquine/therapeutic use ; International Cooperation ; Lopinavir/therapeutic use ; Research Design ; Ritonavir/therapeutic use ; SARS-CoV-2 ; World Health Organization
References:: Adv Drug Deliv Rev. 2018 Aug;133:5-18. (PMID: 29653129)
Clin Trials. 2016 Feb;13(1):92-5. (PMID: 26768564)
Nat Rev Drug Discov. 2019 Jan;18(1):41-58. (PMID: 30310233)
J Infect Dis. 2004 Mar 1;189(5):930-7. (PMID: 14976611)
Evid Based Med. 2010 Dec;15(6):165-6. (PMID: 21106673)
Int J Biol Sci. 2018 Jul 13;14(10):1232-1244. (PMID: 30123072)
JAMA. 2020 Feb 25;323(8):707-708. (PMID: 31971553)
N Engl J Med. 2020 Mar 26;382(13):1268-1269. (PMID: 32109011)
J Pharm Sci. 2019 Feb;108(2):798-806. (PMID: 30244014)
Cell Discov. 2020 Mar 16;6:14. (PMID: 32194980)
Front Oncol. 2017 Nov 14;7:273. (PMID: 29184849)
Bull World Health Organ. 2020 Mar 1;98(3):150. (PMID: 32132744)
Nat Med. 2003 Jul;9(7):839-43. (PMID: 12835701)
Contributed Indexing:: Keywords: COVID-19; Evidence-based medicine; Research ethics; SOLIDARITY; WHO
Substance Nomenclature:: 0 (Antiviral Agents)
0 (Drug Combinations)
0 (lopinavir-ritonavir drug combination)
2494G1JF75 (Lopinavir)
3QKI37EEHE (remdesivir)
415SHH325A (Adenosine Monophosphate)
4QWG6N8QKH (Hydroxychloroquine)
886U3H6UFF (Chloroquine)
O3J8G9O825 (Ritonavir)
OF5P57N2ZX (Alanine)
Entry Date(s):: Date Created: 20200514 Date Completed: 20200617 Latest Revision: 20230106
Update Code:: 20240105
PubMed Central ID:: PMC7216120
DOI:: 10.1007/s00048-020-00257-5
PMID:: 32399903
: Czasopismo naukowe

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This paper is part of Forum COVID-19: Perspectives in the Humanities and Social Sciences. The novel coronavirus (Sars-CoV-2) poses a huge challenge to the world community. Knowledge about the virus and its properties is limited, but there is a great need to base political and medical decisions on scientific knowledge. This situation is leading to a dynamization of research. A prominent example of such a development is SOLIDARITY. The epistemological dimensions of this trial, which is coordinated by the WHO, and the resulting ethical implications are discussed in this article.

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