Clinical profile of symptomatic congenital cytomegalovirus infection: cases from a tertiary hospital in north India.

Szczegóły
Abstrakt

Tytuł:: Clinical profile of symptomatic congenital cytomegalovirus infection: cases from a tertiary hospital in north India.
Autorzy:: Bhattacharya D; Junior Resident, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Panigrahi I; Professor, Genetic Metabolic Unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Chaudhry C; Senior Resident (DM student), Genetic Metabolic Unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Źródło:: Tropical doctor [Trop Doct] 2020 Jul; Vol. 50 (3), pp. 282-284. Date of Electronic Publication: 2020 May 21.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Publication: Oct. 2012- : London : Sage
Original Publication: <1971>-July 2012 : London, Royal Society of Medicine
MeSH Terms:: Cytomegalovirus Infections/*congenital
Cytomegalovirus Infections/*pathology
Cytomegalovirus/isolation & purification ; Cytomegalovirus Infections/diagnosis ; Cytomegalovirus Infections/epidemiology ; Female ; Humans ; India/epidemiology ; Infant ; Infant, Newborn ; Magnetic Resonance Imaging ; Male ; Neuroimaging ; Retrospective Studies ; Tertiary Care Centers
Contributed Indexing:: Keywords: Cytomegalovirus; TORCH; microcephaly; ventriculomegaly
Entry Date(s):: Date Created: 20200522 Date Completed: 20201002 Latest Revision: 20201002
Update Code:: 20240105
DOI:: 10.1177/0049475520923491
PMID:: 32437297
: Czasopismo naukowe

We retrospectively analysed the records of nine infants with polymerase chain reaction proven congenital cytomegalovirus (CMV) infection, of which 66% were born preterm. Microcephaly was a universal finding, followed by hepatosplenomegaly in 89%, while chorioretinitis was seen in only 44% cases. The mean age at diagnosis was 3.5 months. Neuroimaging was abnormal in 78%, with ventriculomegaly being the most common finding followed by T2/FLAIR white matter abnormalities, periventricular cysts and intracranial haemorrhage.

Informacja