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Tytuł:
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Does Gene Expression Noise Play a Functional Role in Plants?
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Autorzy:
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Cortijo S; Sainsbury Laboratory, University of Cambridge, Cambridge CB2 1LR, UK.
Locke JCW; Sainsbury Laboratory, University of Cambridge, Cambridge CB2 1LR, UK. Electronic address: .
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Źródło:
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Trends in plant science [Trends Plant Sci] 2020 Oct; Vol. 25 (10), pp. 1041-1051. Date of Electronic Publication: 2020 May 25.
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Typ publikacji:
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Journal Article; Review
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Język:
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English
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Imprint Name(s):
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Original Publication: Kidlington, Oxford : Elsevier Science, Ltd., c1996-
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MeSH Terms:
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Plants*/genetics
Stress, Physiological*
Gene Expression
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Contributed Indexing:
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Keywords: risk spreading; single-cell RNA-seq; stochasticity; time-lapse microscopy; transcriptional noise
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Entry Date(s):
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Date Created: 20200530 Date Completed: 20201109 Latest Revision: 20201109
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Update Code:
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20240105
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DOI:
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10.1016/j.tplants.2020.04.017
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PMID:
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32467064
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Gene expression in individual cells can be surprisingly noisy. In unicellular organisms this noise can be functional; for example, by allowing a subfraction of the population to prepare for environmental stress. The role of gene expression noise in multicellular organisms has, however, remained unclear. In this review, we discuss how new techniques are revealing an unexpected level of variability in gene expression between and within genetically identical plants. We describe recent progress as well as speculate on the function of transcriptional noise as a mechanism for generating functional phenotypic diversity in plants.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)