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Tytuł:
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LC-MS/MS profiles and interrelationships between the enzyme inhibition activity, total phenolic content and antioxidant potential of Micromeria nervosa extracts.
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Autorzy:
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Sarikurkcu C; Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.
Andrade JC; Federal University of Cariri - UFCA, Juazeiro do Norte, Brazil.
Ozer MS; Manisa Celal Bayar University, Manisa, Turkey.
de Lima Silva JMF; Universitary Center Dr. Leão Sampaio - UNILEÃO, Juazeiro do Norte, Brazil.
Ceylan O; Mugla Sitki Kocman University, Mugla, Turkey.
de Sousa EO; Technological College of Cariri - FATEC, Juazeiro do Norte, Brazil.
Coutinho HDM; Regional University of Cariri - URCA, Crato, Brazil. Electronic address: .
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Źródło:
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Food chemistry [Food Chem] 2020 Oct 30; Vol. 328, pp. 126930. Date of Electronic Publication: 2020 May 25.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: Barking : Elsevier Applied Science Publishers
Original Publication: Barking, Eng., Applied Science Publishers.
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MeSH Terms:
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Tandem Mass Spectrometry*
Antioxidants/*chemistry
Enzyme Inhibitors/*analysis
Lamiaceae/*chemistry
Phenols/*analysis
Plant Extracts/*chemistry
Chromatography, High Pressure Liquid ; Cinnamates/analysis ; Depsides/analysis ; Flavonoids/analysis ; Lamiaceae/metabolism ; Monophenol Monooxygenase/antagonists & inhibitors ; Monophenol Monooxygenase/metabolism ; Plant Components, Aerial/chemistry ; Plant Components, Aerial/metabolism ; alpha-Amylases/antagonists & inhibitors ; alpha-Amylases/metabolism ; Rosmarinic Acid
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Contributed Indexing:
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Keywords: Antioxidant capacity; Phenolic compounds; Rosmarinic acid
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Substance Nomenclature:
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0 (Antioxidants)
0 (Cinnamates)
0 (Depsides)
0 (Enzyme Inhibitors)
0 (Flavonoids)
0 (Phenols)
0 (Plant Extracts)
EC 1.14.18.1 (Monophenol Monooxygenase)
EC 3.2.1.1 (alpha-Amylases)
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Entry Date(s):
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Date Created: 20200603 Date Completed: 20200914 Latest Revision: 20231213
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Update Code:
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20240104
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DOI:
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10.1016/j.foodchem.2020.126930
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PMID:
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32485581
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The objective of this study was to quantify the phenolic compounds and to evaluate and compare the biological activities of the ethyl acetate (EtOAc), methanolic (MeOH) and aqueous extracts from the Micromeria nervosa aerial parts, based on their antioxidant activity and enzymatic inhibition. Total phenolic and flavonoid contents were calculated and individual compo3unds were detected using LC-ESI-MS/MS. The antioxidant activity was determined using six different assays while enzymatic activity was determined by α-amylase and tyrosinase enzyme inhibition. The main phenolic constituents detected in the extracts were rosmarinic acid. In the antioxidant assays the aqueous extract was shown to be more efficient than the others. The EtOAc and MeOH extracts presented higher inhibitory activity with respect to α-amylase and tyrosinase. Regardless of the solvent, the results suggest M. nervosa aerial extracts present a biological potential due to their antioxidant activity and enzymatic inhibition.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
