Sepsis and Septic Shock - Basics of diagnosis, pathophysiology and clinical decision making. - OpacWWW

Szczegóły
Abstrakt

Tytuł:: Sepsis and Septic Shock - Basics of diagnosis, pathophysiology and clinical decision making.
Autorzy:: Font MD; Department of Anesthesiology, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, 1, Medical Center Boulevard, Winston-Salem, NC 27157, USA.
Thyagarajan B; Department of Anesthesiology, Section on Critical Care Medicine, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, 1, Medical Center Boulevard, Winston-Salem, NC 27157, USA.
Khanna AK; Department of Anesthesiology, Section on Critical Care Medicine, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, 1, Medical Center Boulevard, Winston-Salem, NC 27157, USA; Outcomes Research Consortium, Cleveland, OH 44195, USA. Electronic address: .
Źródło:: The Medical clinics of North America [Med Clin North Am] 2020 Jul; Vol. 104 (4), pp. 573-585. Date of Electronic Publication: 2020 May 12.
Typ publikacji:: Journal Article; Review
Język:: English
Imprint Name(s):: Original Publication: Philadelphia, PA : W B Saunders
MeSH Terms:: Clinical Decision-Making*
Organ Dysfunction Scores*
Sepsis/*diagnosis
Shock, Septic/*diagnosis
Blood Pressure/drug effects ; Emergency Service, Hospital ; Hospital Mortality ; Humans ; International Classification of Diseases ; Respiratory Rate ; Sensitivity and Specificity ; Sepsis/physiopathology ; Sepsis/therapy ; Shock, Septic/physiopathology ; Shock, Septic/therapy ; Systemic Inflammatory Response Syndrome/diagnosis ; Terminology as Topic ; Vasoconstrictor Agents/therapeutic use
Contributed Indexing:: Keywords: Critical care; SIRS; Sepsis; Septic shock; Vasopressors; qSOFA
Substance Nomenclature:: 0 (Vasoconstrictor Agents)
Entry Date(s):: Date Created: 20200608 Date Completed: 20200617 Latest Revision: 20200617
Update Code:: 20240104
DOI:: 10.1016/j.mcna.2020.02.011
PMID:: 32505253
: Czasopismo naukowe

Sepsis and septic shock are major causes of mortality among hospitalized patients. The sepsis state is due to dysregulated host response to infection, leading to inflammatory damage to nearly every organ system. Early recognition of sepsis and appropriate treatment with antibiotics, fluids, and vasopressors is essential to reducing organ system injury and mortality. This review summarizes the current understanding of the epidemiology, pathophysiology, diagnosis, and treatment of sepsis and septic shock.
Competing Interests: Disclosure Departmental resources supported this work. The authors have nothing to disclose.
(Copyright © 2020 Elsevier Inc. All rights reserved.)

Informacja

Sepsis and Septic Shock - Basics of diagnosis, pathophysiology and clinical decision making.