[Research status of and treatment progress in chronic myeloid leukemia in children].

Szczegóły

Tytuł:: [Research status of and treatment progress in chronic myeloid leukemia in children].
Autorzy:: Liang WR; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Yang WY; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Źródło:: Zhonghua er ke za zhi = Chinese journal of pediatrics [Zhonghua Er Ke Za Zhi] 2020 Jun 02; Vol. 58 (6), pp. 516-519.
Typ publikacji:: Journal Article; Review
Język:: Chinese
Imprint Name(s):: Original Publication: Beijing : Chinese Medical Association, 1950
MeSH Terms:: Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*therapy
Child ; Hematopoietic Stem Cell Transplantation/methods ; Humans
Contributed Indexing:: Local Abstract: [Publisher, Chinese] 慢性粒细胞白血病（CML）在儿童中相对罕见，其临床表现、免疫表型及遗传学特征与成年患者存在差异。CML患儿处于特殊的成长时期，可能接受长达数十年的酪氨酸抑制剂（TKI）治疗，不良反应发生率可能高于成年患者。与成年CML患者相比，首诊CML患儿的TKI药物选择仍需要探讨，造血干细胞移植的地位存在争议。本文对儿童CML的研究现状、TKI时代患儿用药、疗效监测及移植时机选择进行综述。.
Entry Date(s):: Date Created: 20200612 Date Completed: 20200910 Latest Revision: 20200910
Update Code:: 20240104
DOI:: 10.3760/cma.j.cn112140-20191108-00707
PMID:: 32521968
: Czasopismo naukowe

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