Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ
Tytuł pozycji:

Roles of long non-coding RNAs in cervical cancer.

Tytuł :
Roles of long non-coding RNAs in cervical cancer.
Autorzy :
Luo F; Institute of Pathogenic Biology, Hengyang Medical College, Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang 421001, China.
Wen Y; Institute of Pathogenic Biology, Hengyang Medical College, Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang 421001, China.
Zhou H; Department of Laboratory Medicine, The First Hospital of Hunan University of Chinese Medicine, Changsha 410007, China. Electronic address: .
Li Z; Institute of Pathogenic Biology, Hengyang Medical College, Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang 421001, China. Electronic address: .
Pokaż więcej
Źródło :
Life sciences [Life Sci] 2020 Sep 01; Vol. 256, pp. 117981. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji :
Journal Article; Review
Język :
English
Imprint Name(s) :
Publication: <2008->: Amsterdam : Elsevier
Original Publication: Oxford; Elmsford, N. Y. [etc.] Pergamon Press.
MeSH Terms :
RNA, Long Noncoding/*genetics
RNA, Long Noncoding/*metabolism
Uterine Cervical Neoplasms/*genetics
Uterine Cervical Neoplasms/*metabolism
Animals ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Cell Proliferation/physiology ; Female ; Humans ; Uterine Cervical Neoplasms/therapy
Contributed Indexing :
Keywords: Biologic functions; Biomarkers; Cervical cancer; LncRNAs
Substance Nomenclature :
0 (Biomarkers, Tumor)
0 (RNA, Long Noncoding)
Entry Date(s) :
Date Created: 20200621 Date Completed: 20200831 Latest Revision: 20200831
Update Code :
20201023
DOI :
10.1016/j.lfs.2020.117981
PMID :
32561395
Czasopismo naukowe
Cervical cancer (CC) is regarded as the second serious threat to women's health worldwide; it's associated with certain viruses that are transmitted through sexual intercourse. Therefore, the pathogenesis of CC remains to be studied. The identified long non-coding RNAs (lncRNAs) as a key genomic product were found to be commonly dysregulated in CC and to exert significant effects in the initiation, migration, invasion and therapeutic response of CC. Therefore lncRNAs may be used as tumor suppressor genes or oncogenes to interact with DNA, RNA or proteins for the regulation of gene expression and cell signaling pathways. The relationship between single lncRNA and CC has been discovered. However, full-scale reviews on the lncRNAs function in CC are deficiency. In this review, we describe the recent reports on the dysregulated patterns regulation of lncRNAs in CC. We also conclude the recent advances on biologic functions and molecular regulation mechanism and potential clinical application of lncRNAs in CC.
(Copyright © 2020. Published by Elsevier Inc.)

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies