MS4A4A Regulates Arginase 1 Induction during Macrophage Polarization and Lung Inflammation in Mice.

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Abstrakt

Tytuł:: MS4A4A Regulates Arginase 1 Induction during Macrophage Polarization and Lung Inflammation in Mice.
Autorzy:: Sui Y; Institute for Immunology and School of Medicine, Center for Life Sciences, Tsinghua University, Beijing, China.; Beijing Key Laboratory for Immunological Research on Chronic Diseases, Beijing, China.; School of Life Science, Tsinghua University, Beijing, China.
Zeng W; Institute for Immunology and School of Medicine, Center for Life Sciences, Tsinghua University, Beijing, China.; Beijing Key Laboratory for Immunological Research on Chronic Diseases, Beijing, China.
Źródło:: European journal of immunology [Eur J Immunol] 2020 Oct; Vol. 50 (10), pp. 1602-1605. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji:: Letter; Research Support, Non-U.S. Gov't
Język:: English
Imprint Name(s):: Publication: <2005->: Weinheim : Wiley-VCH
Original Publication: Weinheim, Verlag Chemie GmbH.
MeSH Terms:: Arginase/*metabolism
Eosinophils/*immunology
Hypersensitivity/*immunology
Lung/*immunology
Macrophages/*physiology
Membrane Proteins/*metabolism
Pneumonia/*immunology
Animals ; Antigens, Dermatophagoides/immunology ; Arginase/genetics ; Cell Differentiation ; Macrophage Activation ; Membrane Proteins/genetics ; Mice ; Mice, Knockout ; Pyroglyphidae ; Up-Regulation
References:: Ginhoux, F. et al., Immunity. 2016. 44(3): 439-449.
Perdiguero, E. G. et al., Nat. Immunol. 2016. 17(1): 2-8.
Lawrence, T. et al., Nat. Rev. Immunol. 2011. 11(11): 750-761.
Mosser, D. M. et al., Nat. Rev. Immunol. 2008. 8(12): 958-969.
Mattiola, I. et al., Nat. Immunol. 2019. 20(8): 1012-1022.
Sanyal, R. et al., Immunol. Cell Biol. 2017. 95(7): 611-619.
Reese, T. A. et al., Nature. 2007. 447(7140): 92-96.
Roszer, T., Mediators Inflamm. 2015. 2015816460.
Aun, M. V. et al., J. Asthma Allergy. 2017. 10293-10301. https://doi.org/10.2147/JAA.S121092.
Grant Information:: 2017YFA0505800 International National Key R&D Program of China; 91742106 International National Natural Science Foundation of China; 31822018 International National Natural Science Foundation of China; 31770936 International National Natural Science Foundation of China
Contributed Indexing:: Keywords: IL4; MS4A4A; allergic immunity; arginase 1; macrophage
Substance Nomenclature:: 0 (Antigens, Dermatophagoides)
0 (Membrane Proteins)
0 (Ms4a4b protein, mouse)
EC 3.5.3.1 (Arg1 protein, mouse)
EC 3.5.3.1 (Arginase)
Entry Date(s):: Date Created: 20200627 Date Completed: 20210111 Latest Revision: 20210111
Update Code:: 20240105
DOI:: 10.1002/eji.202048585
PMID:: 32589266
: Raport

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MS4A4A regulates the expression of arginase 1 in macrophages under IL4 stimulation. Also, MS4A4A regulates eosinophil infiltration during lung allergic inflammation induced by intranasal administration of house dust mite.
(© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

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