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Tytuł:
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Clash of the cascades: Release the inhibition.
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Autorzy:
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Currier BS; Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada.
Joanisse S; Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada.
McKendry J; Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada.
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Źródło:
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The Journal of physiology [J Physiol] 2020 Oct; Vol. 598 (19), pp. 4153-4154. Date of Electronic Publication: 2020 Jul 23.
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Typ publikacji:
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Journal Article; Comment
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Język:
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English
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Imprint Name(s):
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Publication: Oxford : Blackwell : Cambridge Univ. Press
Original Publication: London, Cambridge Univ. Press.
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MeSH Terms:
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AMP-Activated Protein Kinases*
Glycogen*
Mechanistic Target of Rapamycin Complex 1 ; Muscle, Skeletal ; TOR Serine-Threonine Kinases
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References:
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Dreyer HC, Fujita S, Cadenas JG, Chinkes DL, Volpi E & Rasmussen BB (2006). Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle. J Physiol 576, 613-624.
Knudsen JR, Li Z, Persson KW, Li J, Henriquez-Olguin C & Jensen TE (2020). Contraction-regulated mTORC1 and protein synthesis: Influence of AMPK and glycogen. J Physiol 598, 2637-2649.
Ljubicic V, Adhihetty PJ & Hood DA (2005). Application of animal models: chronic electrical stimulation-induced contractile activity. Can J Appl Physiol 30, 625-643.
West DW, Baehr LM, Marcotte GR, Chason CM, Tolento L, Gomes AV, Bodine SC & Baar K (2016). Acute resistance exercise activates rapamycin-sensitive and -insensitive mechanisms that control translational activity and capacity in skeletal muscle. J Physiol 594, 453-468.
You JS, McNally RM, Jacobs BL, Privett RE, Gundermann DM, Lin KH, Steinert ND, Goodman CA & Hornberger TA (2019). The role of raptor in the mechanical load-induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy. FASEB J 33, 4021-4034.
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Contributed Indexing:
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Keywords: AMPK; glycogen; mTOR; protein synthesis; resistance exercise
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Substance Nomenclature:
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9005-79-2 (Glycogen)
EC 2.7.11.1 (Mechanistic Target of Rapamycin Complex 1)
EC 2.7.11.1 (TOR Serine-Threonine Kinases)
EC 2.7.11.31 (AMP-Activated Protein Kinases)
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Entry Date(s):
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Date Created: 20200707 Date Completed: 20210129 Latest Revision: 20211204
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Update Code:
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20240105
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DOI:
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10.1113/JP280253
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PMID:
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32628271
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Comment on: J Physiol. 2020 Jul;598(13):2637-2649. (PMID: 32372406)