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Tytuł:
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Trypanosoma, Paramecium and Tetrahymena: From genomics to flagellar and ciliary structures and cytoskeleton dynamics.
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Autorzy:
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Soares H; Centro de Química Estrutural, Faculdade de Ciências, Universidade de Lisboa, Lisboa, Portugal; Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa, Lisboa, Portugal.
Sunter JD; Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, UK.
Wloga D; Laboratory of Cytoskeleton and Cilia Biology, Nencki Institute, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.
Joachimiak E; Laboratory of Cytoskeleton and Cilia Biology, Nencki Institute, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.
Miceli C; School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy. Electronic address: .
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Źródło:
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European journal of protistology [Eur J Protistol] 2020 Oct; Vol. 76, pp. 125722. Date of Electronic Publication: 2020 Jun 10.
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Typ publikacji:
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Journal Article; Review
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Język:
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English
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Imprint Name(s):
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Publication: Stuttgart : Gustav Fischer Verlag
Original Publication: Stuttgart ; New York : G. Fischer, c1987-
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MeSH Terms:
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Paramecium*/genetics
Paramecium*/ultrastructure
Tetrahymena*/genetics
Tetrahymena*/ultrastructure
Trypanosoma*/genetics
Trypanosoma*/ultrastructure
Cytoskeleton/*ultrastructure
Genome, Protozoan/*genetics
Cilia/genetics ; Congresses as Topic ; Flagella/genetics
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Contributed Indexing:
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Keywords: Cell motility; Ciliogenesis; Organelle asymmetry; Protozoa
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Entry Date(s):
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Date Created: 20200718 Date Completed: 20201204 Latest Revision: 20201214
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Update Code:
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20240105
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DOI:
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10.1016/j.ejop.2020.125722
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PMID:
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32679518
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Cilia and flagella play an important role in motility, sensory perception, and the life cycles of eukaryotes, from protists to humans. However, much critical information concerning cilia structure and function remains elusive. The vast majority of ciliary and flagellar proteins analyzed so far are evolutionarily conserved and play a similar role in protozoa and vertebrates. This makes protozoa attractive biological models for studying cilia biology. Research conducted on ciliated or flagellated protists may improve our general understanding of cilia protein composition, of cilia beating, and can shed light on the molecular basis of the human disorders caused by motile cilia dysfunction. The Symposium "From genomics to flagellar and ciliary structures and cytoskeleton dynamics" at ECOP2019 in Rome presented the latest discoveries about cilia biogenesis and the molecular mechanisms of ciliary and flagellum motility based on studies in Paramecium, Tetrahymena, and Trypanosoma. Here, we review the most relevant aspects presented and discussed during the symposium and add our perspectives for future research.
(Crown Copyright © 2020. Published by Elsevier GmbH. All rights reserved.)
