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Tytuł pozycji:

Molecular pathogenesis of secondary bacterial infection associated to viral infections including SARS-CoV-2.

Tytuł:
Molecular pathogenesis of secondary bacterial infection associated to viral infections including SARS-CoV-2.
Autorzy:
Manna S; Department of Microbiology, Midnapore College (Autonomous), Paschim Medinipur, India.
Baindara P; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, USA.
Mandal SM; Central Research Facility, Indian Institute of Technology Kharagpur, Kharagpur 721302, India. Electronic address: .
Źródło:
Journal of infection and public health [J Infect Public Health] 2020 Oct; Vol. 13 (10), pp. 1397-1404. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji:
Journal Article; Review
Język:
English
Imprint Name(s):
Original Publication: Oxford : Elsevier, 2008-
MeSH Terms:
Bacterial Infections/*immunology
Bacterial Infections/*virology
Coronavirus Infections/*immunology
Influenza, Human/*immunology
Pneumonia, Viral/*immunology
Adaptive Immunity ; Bacteria/growth & development ; Bacterial Adhesion ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Humans ; Immune Tolerance ; Immunity, Innate ; Inflammation/complications ; Influenza, Human/complications ; Microbial Interactions ; Pandemics ; Patient Acuity ; Pneumonia, Viral/complications ; SARS-CoV-2
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Contributed Indexing:
Keywords: Immune response; SARS-CoV-2; Secondary bacterial infection; Viral infection
Entry Date(s):
Date Created: 20200727 Date Completed: 20201013 Latest Revision: 20230306
Update Code:
20240105
PubMed Central ID:
PMC7359806
DOI:
10.1016/j.jiph.2020.07.003
PMID:
32712106
Czasopismo naukowe
Secondary bacterial infections are commonly associated with prior or concomitant respiratory viral infections. Viral infections damage respiratory airways and simultaneously defects both innate and acquired immune response that provides a favorable environment for bacterial growth, adherence, and facilitates invasion into healthy sites of the respiratory tract. Understanding the molecular mechanism of viral-induced secondary bacterial infections will provide us a chance to develop novel and effective therapeutic approaches for disease prevention. The present study describes details about the secondary bacterial infection during viral infections and their immunological changes.The outcome of discussion avails an opportunity to understand possible secondary bacterial infections associated with novel SARS-CoV-2, presently causing pandemic outbreak COVID-19.
(Copyright © 2020. Published by Elsevier Ltd.)

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