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Tytuł pozycji:

Peruvian Valuation of the EQ-5D-5L: A Direct Comparison of Time Trade-Off and Discrete Choice Experiments.

Tytuł :
Peruvian Valuation of the EQ-5D-5L: A Direct Comparison of Time Trade-Off and Discrete Choice Experiments.
Autorzy :
Augustovski F; Institute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.
Belizán M; Institute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.
Gibbons L; Institute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.
Reyes N; Unidad de Análisis y Generación de Evidencias en Salud Pública, Instituto Nacional de la Salud, Lima, Perú.
Stolk E; EuroQol Research Foundation, Rotterdam, The Netherlands.
Craig BM; University of South Florida, Tampa, FL, USA.
Tejada RA; Unidad de Análisis y Generación de Evidencias en Salud Pública, Instituto Nacional de la Salud, Lima, Perú. Electronic address: .
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Źródło :
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research [Value Health] 2020 Jul; Vol. 23 (7), pp. 880-888. Date of Electronic Publication: 2020 Jul 18.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Język :
English
Imprint Name(s) :
Publication: Jan./Feb. 2011- : New York : Elsevier
Original Publication: Malden, MA : Blackwell Science, c1998-
MeSH Terms :
Choice Behavior*
Models, Theoretical*
Quality-Adjusted Life Years*
Surveys and Questionnaires*
Adult ; Female ; Health Status ; Humans ; Male ; Middle Aged ; Peru ; Quality of Life ; Time Factors
Contributed Indexing :
Keywords: EuroQol*; discrete choice experiment*; preference elicitation methods*; time trade off*; utility assessment*
Entry Date(s) :
Date Created: 20200809 Date Completed: 20200922 Latest Revision: 20200922
Update Code :
20201023
DOI :
10.1016/j.jval.2020.05.004
PMID :
32762989
Czasopismo naukowe
Objectives: (1) To produce Peruvian general population EQ-5D-5L value sets on a quality-adjusted life-year scale, (2) to investigate the feasibility of a "Lite" protocol less reliant on the composite time trade-off (cTTO), and (3) to compare cTTO and discrete choice experiment (DCE) value sets.
Methods: A random sample of adults (N = 1000) in Lima, Arequipa, and Iquitos did a home interview; 300 were randomly selected to complete 11 cTTOs first. All respondents completed a DCE, including 10 latent-scale pairs (A/B) with 5 EQ-5D-5L attributes, and 12 matched pairs (A/B and B/C) with 5 EQ-5D-5L and one lifespan attributes. We estimated a cTTO heteroscedastic tobit (N = 300) model and 3 DCE Zermelo-Bradley-Terry models (N = 300, 700, and 1000).
Results: Each model produced a consistent value set (20 positive incremental parameters). Nevertheless, their lowest quality-adjusted life-year values differed greatly (cTTO: -1.076 [N = 300]; DCE: -0.984 [300], 0.048 [700], -0.213 [1000]). Compared with the cTTO, the DCE (N = 300) produced different parameters (Pearson's correlation = 0.541), fewer insignificant parameters (0 vs 8), and fewer values less than 0 (26% vs 44%). Compared with the DCE (N = 300), the DCE (N = 700) produced higher values but similar parameters (Pearson's correlation = 0.800).
Conclusions: Besides producing EQ-5D-5L value sets for Peru, the results casts doubt about the feasibility of a Lite protocol like the one in this study. Additionally, fundamental differences between cTTO and DCE-without the existence of a gold standard-need further clarification. The choice between the two rational value sets produced in the current study is a matter of judgment and may have substantial policy implications.
(Copyright © 2020 ISPOR–The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc. All rights reserved.)

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