Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure.

Szczegóły
Abstrakt

Tytuł:: Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure.
Autorzy:: Muns SM; Department of Ophthalmology, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936-5067 USA.
González MP; Department of Ophthalmology, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936-5067 USA.
Villegas VM; Department of Ophthalmology, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936-5067 USA.; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136 USA.; Department of Surgery, Ponce Health Sciences University, Ponce, PR 00732-7004 USA.
de la Vega G; Department of Radiology, HIMA San Pablo Hospital, Caguas, PR 00726-4980 USA.
Ventura CV; Department of Ophthalmology, Altino Ventura Foundation, Recife, Brazil.; Department of Ophthalmology, HOPE Eye Hospital, Recife, Brazil.
Berrocal AM; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136 USA.
Źródło:: International journal of retina and vitreous [Int J Retina Vitreous] 2020 Aug 01; Vol. 6, pp. 36. Date of Electronic Publication: 2020 Aug 01 (Print Publication: 2020).
Typ publikacji:: Case Reports
Język:: English
Imprint Name(s):: Original Publication: London : BioMed Central, [2015]-
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Contributed Indexing:: Keywords: Coloboma; Excavated disc anomaly; Morning glory disc anomaly; Optic disc; Zika virus
Entry Date(s):: Date Created: 20200809 Latest Revision: 20220416
Update Code:: 20240105
PubMed Central ID:: PMC7395399
DOI:: 10.1186/s40942-020-00240-1
PMID:: 32765899
: Raport

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Background: To report a case of morning glory disc anomaly (MGDA) in a pediatric patient with prenatal Zika virus (ZIKV) exposure.
Case Presentation: A 3-year-old male with prenatal exposure to ZIKV, confirmed by real-time polymerase chain reaction testing during the second trimester of pregnancy, was evaluated due to visual loss. Physical examination was remarkable for unilateral MGDA. Neuroimaging showed a base of skull encephalocele through the floor of the sella and callosal dysgenesis.
Conclusions: This is the first report to suggest an association between prenatal ZIKV exposure and MGDA. Prenatal ZIKV exposure may be associated to a wider pathologic spectrum than previously reported.
Competing Interests: Competing interestsThe authors declare that they have no competing interests.
(© The Author(s) 2020.)

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