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Tytuł pozycji:

In Vitro Whitening Effect of a Hydroxyapatite-Based Oral Care Gel.

Tytuł :
In Vitro Whitening Effect of a Hydroxyapatite-Based Oral Care Gel.
Autorzy :
Sarembe S; Fraunhofer Institute for Microstructure of Materials and Systems IMWS, Halle, Germany.
Enax J; Research Department, Dr. Kurt Wolff GmbH and Co. KG, Bielefeld, Germany.
Morawietz M; Fraunhofer Institute for Microstructure of Materials and Systems IMWS, Halle, Germany.
Kiesow A; Fraunhofer Institute for Microstructure of Materials and Systems IMWS, Halle, Germany.
Meyer F; Research Department, Dr. Kurt Wolff GmbH and Co. KG, Bielefeld, Germany.
Pokaż więcej
Źródło :
European journal of dentistry [Eur J Dent] 2020 Jul; Vol. 14 (3), pp. 335-341. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article
Język :
English
Imprint Name(s) :
Publication: [2019]- : [Stuttgart] : Thieme
Original Publication: Ankara : Dental Investigations Society
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Entry Date(s) :
Date Created: 20200814 Latest Revision: 20200928
Update Code :
20210623
PubMed Central ID :
PMC7440957
DOI :
10.1055/s-0040-1714759
PMID :
32791529
Czasopismo naukowe
Objective:  Oral care formulations aim to prevent oral diseases such as dental caries and gingivitis. Additionally, desire for white teeth still exists across all age groups. It is known that most whitening toothpastes are highly abrasive and can be harmful to teeth and gingiva. Therefore, a gel formulation with biomimetic hydroxyapatite (HAP; Ca 5 [PO 4 ] 3 [OH]) as active ingredient was developed. This formulation was tested with respect to its tooth whitening properties in an in vitro study.
Materials and Methods:  Enamel samples were allocated to either group (a) HAP gel, (b) whitening mouth rinse with phosphates, or (c) negative control (distilled water). Test products were applied by finger (a) or were rinsed (b, c) for 1, 3, and 9 (b and c only) cycles, respectively.
Results:  Color changes (ΔE) were measured spectrophotometrically. Group (a) showed a significant increase in color changes with respect to whitening after one cycle (mean ΔE = 5.4 [±2.66], p  ≤ 0.006) and three cycles (mean ΔE = 11.2 [±3.11], p < 0.0001) compared to groups (b) and (c). For group (b), a significant increase in color change was measured after three (mean ΔE = 2.77 [±1.01], p = 0.02) and nine cycles (mean ΔE = 3.27 [±1.61], p = 0.006) compared to (c). Group (c) showed only minor and statistically insignificant color changes.
Conclusion:  This in vitro study demonstrated a significantly higher ad hoc whitening effect of the HAP gel compared to the mouth rinse and water after short-time application.

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