ENDOPHTHALMITIS AFTER TRANSCONJUNCTIVAL PARS PLANA VITRECTOMY: A 6-year Experience Without Prophylactic Intraoperative Subconjunctival Antibiotics.

Szczegóły
Abstrakt

Tytuł:: ENDOPHTHALMITIS AFTER TRANSCONJUNCTIVAL PARS PLANA VITRECTOMY: A 6-year Experience Without Prophylactic Intraoperative Subconjunctival Antibiotics.
Autorzy:: LaGrow AL; University of Oklahoma College of Medicine, Oklahoma City, Oklahoma.
Schatzman SN; University of Oklahoma College of Medicine, Oklahoma City, Oklahoma.
Amayem OA; University of Oklahoma College of Medicine, Oklahoma City, Oklahoma.
Bradford RH; Dean McGee Eye Institute, Oklahoma City, Oklahoma.; Department of Ophthalmology, University of Oklahoma College of Medicine, Oklahoma City, Oklahoma.
Shah VA; Dean McGee Eye Institute, Oklahoma City, Oklahoma.; Department of Ophthalmology, University of Oklahoma College of Medicine, Oklahoma City, Oklahoma.
Chen S; Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center; and.
Lee SY; Dean McGee Eye Institute, Oklahoma City, Oklahoma.; Department of Ophthalmology, University of Oklahoma College of Medicine, Oklahoma City, Oklahoma.; Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Źródło:: Retina (Philadelphia, Pa.) [Retina] 2021 Mar 01; Vol. 41 (3), pp. 531-537.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: Philadelphia : Lippincott, [1981?-
MeSH Terms:: Intraoperative Care*
Endophthalmitis/*epidemiology
Eye Infections, Bacterial/*epidemiology
Surgical Wound Infection/*epidemiology
Vitrectomy/*adverse effects
Anti-Bacterial Agents/administration & dosage ; Antibiotic Prophylaxis ; Conjunctiva ; Endophthalmitis/prevention & control ; Eye Infections, Bacterial/prevention & control ; Female ; Follow-Up Studies ; Humans ; Incidence ; Injections ; Male ; Middle Aged ; Retrospective Studies ; Surgical Wound Infection/prevention & control ; Time Factors ; United States/epidemiology
References:: Ho PC, Tolentino FI. Bacterial endophthalmitis after closed vitrectomy. Arch Ophthalmol 1984;102:207–210.
Eifrig CW, Scott IU, Flynn HW Jr, et al. Endophthalmitis after pars plana vitrectomy: incidence, causative organisms, and visual acuity outcomes. Am J Ophthalmol 2004;138:799–802.
Kunimoto DY, Kaiser RS. Wills Eye Retina Service. Incidence of endophthalmitis after 20- and 25-gauge vitrectomy. Ophthalmology 2007;114:2133–2137.
Scott IU, Flynn HW Jr, Dev S, et al. Endophthalmitis after 25-gauge and 20-gauge pars plana vitrectomy: incidence and outcomes. Retina 2008;28:138–142.
Hu AY, Bourges JL, Shah SP, et al. Endophthalmitis after pars plana vitrectomy a 20- and 25-gauge comparison. Ophthalmology 2009;116:1360–1365.
Oshima Y, Kadonosono K, Yamaji H, et al. Multicenter survey with a systematic overview of acute-onset endophthalmitis after transconjunctival microincision vitrectomy surgery. Am J Ophthalmol 2010;150:716–725.e1.
Weiss SJ, Adam MK, Gao X, et al. Endophthalmitis following pars plana vitrectomy: efficacy of intraoperative subconjunctival antibiotics. Retina 2018;38:1848–1855.
Javitt JC, Street DA, Tielsch JM, et al. National outcomes of cataract extraction. Retinal detachment and endophthalmitis after outpatient cataract surgery. Cataract Patient Outcomes Research Team. Ophthalmology 1994;101:100–105.
Aaberg TM Jr, Flynn HW Jr, Schiffman J, et al. Nosocomial acute-onset postoperative endophthalmitis survey. A 10-year review of incidence and outcomes. Ophthalmology 1998;105:1004–1010.
Keay L, Gower EW, Cassard SD, et al. Postcataract surgery endophthalmitis in the United States: analysis of the complete 2003 to 2004 Medicare database of cataract surgeries. Ophthalmology 2012;119:914–922.
Olson RJ, Braga-Mele R, Chen SH, et al. Cataract in the adult eye preferred practice pattern. Ophthalmology 2017;124:1–119.
Kaiser RS, Prenner J, Scott IU, et al. The Microsurgical Safety Task Force: evolving guidelines for minimizing the risk of endophthalmitis associated with microincisional vitrectomy surgery. Retina 2010;30:692–699.
Shah RE, Gupta O. The microsurgical safety task force: guidelines for minimizing endophthalmitis with vitrectomy surgery. Curr Opin Ophthalmol 2012;23:189–194.
Wu L, Berrocal MH, Arévalo JF, et al. Endophthalmitis after pars plana vitrectomy: results of the Pan American Collaborative Retina Study Group. Retina 2011;31:673–678.
Chen JK, Khurana KRN, Nguyen NQD, et al. The incidence of endophthalmitis following transconjunctival sutureless 25- vs 20-gauge vitrectomy. Eye 2009;23:780–784.
Wani VB, Al Sabti K, Kumar N, et al. Endophthalmitis after vitrectomy and vitrectomy combined with phacoemulsification: incidence and visual outcomes. Eur J Ophthalmol 2009;19:1044–1049.
Speaker MG, Menikoff JA. Prophylaxis of endophthalmitis with topical povidone-iodine. Ophthalmology 1991;98:1769–1717.
Bhende M, Raman R, Jain M, et al.; Sankara Nethralaya Vitreoretinal Study Group (SNVR-Study Group). Incidence, microbiology, and outcomes of endophthalmitis after 111,876 pars plana vitrectomies at a single, tertiary eye care hospital. PLoS One 2018;16:e0191173.
Phillips WB II, Tasman WS. Postoperative endophthalmitis in association with diabetes mellitus. Ophthalmology 1994;101:508–518.
Oshima Y, Ohji M, Tano Y. Surgical outcomes of 25-gauge transconjunctival vitrectomy combined with cataract surgery for vitreoretinal diseases. Ann Acad Med Singapore 2006;35:175–180.
Querques L, Miserocchi E, Modorati G, et al. Hemorrhagic occlusive retinal vasculitis after inadvertent intraocular perforation with gentamycin injection. Eur J Ophthalmol 2017;27:e50–53.
Gadkari SS. Evaluation of 19 cases of inadvertent globe perforation due to periocular injections. Indian J Ophthalmol 2007;55:103–107.
Berrocal AM, Schuman JS. Subconjunctival cephalosporin anaphylaxis. Ophthalmic Surg Lasers 2001;32:79–80.
CDC issues recommendations for preventing spread of vancomycin resistance. Am J Health Syst Pharm 1995;52:1272–1274.
Berríos-Torres SI, Umscheid CA, Bratzler DW, et al. Healthcare Infection Control Practices Advisory Committee. Centers for Diseases Control and Prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg 2017;152:784–791.
Grant Information:: U54 GM104938 United States GM NIGMS NIH HHS
Substance Nomenclature:: 0 (Anti-Bacterial Agents)
Entry Date(s):: Date Created: 20200823 Date Completed: 20211116 Latest Revision: 20230816
Update Code:: 20240105
PubMed Central ID:: PMC7889285
DOI:: 10.1097/IAE.0000000000002905
PMID:: 32826794
: Czasopismo naukowe

Purpose: This study aimed to investigate the incidence and risk factors of endophthalmitis after transconjunctival pars plana vitrectomy (PPV) without intraoperative subconjunctival antibiotics.
Design: Retrospective, consecutive case series at a single institution.
Methods: Consecutive cases of transconjunctival 25-gauge PPV without intraoperative subconjunctival antibiotics performed by three retina surgeons at a single surgical site at the Dean McGee Eye Institute from 2012 to 2018 were reviewed.
Results: Of 4,263 cases of PPV without intraoperative subconjunctival antibiotics, five cases (0.117%, 5/4,263) of post-PPV endophthalmitis were identified. Of these five cases, four cases (80%, 4/5) received combined cataract extraction or secondary intraocular lens implantation at the time of PPV. The incidence of endophthalmitis in isolated PPV was 0.027% (1/3,606 cases), whereas the incidence in combined PPV with anterior segment procedures was 0.608% (4/657 cases). Risk factors for endophthalmitis included diabetes mellitus, which was present in 80% of patients with endophthalmitis (4/5 cases). Causative organisms were identified in four of the five cases (80%), including Staphylococcus epidermidis (N = 3) and Propionibacterium acnes (N = 1).
Conclusion: Performing transconjunctival PPV alone with standard preparation using povidone-iodine and postoperative topical antibiotics for 1 week without intraoperative subconjunctival antibiotics did not lead to an increase in incidence of postoperative endophthalmitis (1 per 3,606 cases).
(Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Opthalmic Communications Society, Inc.)

Informacja