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Tytuł:
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Pancreatic perfusion imaging method that reduces radiation dose and maintains image quality by combining volumetric perfusion CT with multiphasic contrast enhanced-CT.
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Autorzy:
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Konno Y; Department of Diagnostic Radiology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata-shi, Yamagata, 990-9585, Japan. Electronic address: .
Hiraka T; Department of Diagnostic Radiology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata-shi, Yamagata, 990-9585, Japan.
Kanoto M; Department of Diagnostic Radiology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata-shi, Yamagata, 990-9585, Japan.
Sato T; Department of Radiology, Yamagata University Hospital, Japan.
Tsunoda M; Department of Gastroenterology, Faculty of Medicine, Yamagata University, Japan.
Ishizawa T; Department of Gastroenterology, Faculty of Medicine, Yamagata University, Japan.
Matsuda A; Department of Gastroenterology, Faculty of Medicine, Yamagata University, Japan.
Makino N; Department of Gastroenterology, Faculty of Medicine, Yamagata University, Japan.
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Źródło:
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Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] [Pancreatology] 2020 Oct; Vol. 20 (7), pp. 1406-1412. Date of Electronic Publication: 2020 Aug 27.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: 2012- : New Delhi : Elsevier India
Original Publication: Basel ; New York : Karger, c2001-
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MeSH Terms:
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Contrast Media*
Pancreas/*diagnostic imaging
Perfusion Imaging/*methods
Radiation Injuries/*prevention & control
Tomography, X-Ray Computed/*methods
Adult ; Aged ; Aged, 80 and over ; Aorta/diagnostic imaging ; Female ; Humans ; Image Processing, Computer-Assisted ; Male ; Middle Aged ; Observer Variation ; Pancreatic Neoplasms/diagnostic imaging ; Radiation Dosage ; Reproducibility of Results ; Signal-To-Noise Ratio
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Contributed Indexing:
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Keywords: Broad clinical use; Diagnostic imaging; Pancreatic cancer; Single examination
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Substance Nomenclature:
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0 (Contrast Media)
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Entry Date(s):
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Date Created: 20200905 Date Completed: 20210917 Latest Revision: 20210917
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Update Code:
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20240104
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DOI:
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10.1016/j.pan.2020.08.010
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PMID:
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32888809
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Objectives: The aim of this study is to propose and evaluate a new method of volumetric perfusion computed tomography (PCT) incorporated into pancreatic multiphasic contrast enhanced (CE)-CT in the clinical setting.
Methods: In this ethically approved study, PCT was incorporated into our existing scanning protocol in 17 patients and effective doses related to PCT were evaluated. CT values and signal-to-noise ratio (SNR) of anatomical structure were compared in diagnostic images that were acquired using 320-detector volumetric scan mode and 64-detector helical scan mode. In addition, focal lesion depiction was qualitatively assessed in the two groups. Perfusion parameters in normal pancreas were measured by two radiologists and the interobserver-reliability was assessed.
Results: The effective dose of PCT was 5.1 ± 0.3 mSv. The actual effective dose (AED) including the dose used in volumetric scans for diagnostic imaging was 22.8 ± 5.3 mSv and the putative effective dose (PED) was 21.9 ± 9.1 mSv on average. There was no significant difference between AED and PED (p = 0.404). Compared with conventional helical scans, volumetric scans did not decrease CT values or SNR, but rather significantly increased those of the aorta in the arterial phase. Both groups had acceptable qualitatively assessed image quality with no significant difference in the depiction of each structure. There was almost perfect interobserver agreement in the measurement of perfusion parameters (mean ICCs > 0.9).
Conclusions: Our scanning protocol for pancreatic perfusion CT provides high-quality images while requiring lower radiation doses than conventional methods.
(Copyright © 2020 IAP and EPC. Published by Elsevier B.V. All rights reserved.)
