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Tytuł:
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Cerebral Arteriovenous Malformations as Acquired Lesions: Case Reports and Review of the Literature.
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Autorzy:
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Nagai Y; Department of Neurosurgery, National Hospital Organization Beppu Medical Center, 1473 Uchikamado, Beppu, Oita 8740011, Japan. Electronic address: .
Anan M; Department of Neurosurgery, National Hospital Organization Beppu Medical Center, 1473 Uchikamado, Beppu, Oita 8740011, Japan.
Fujiki M; Department of Neurosurgery, Oita University Faculty of Medicine, 1-1 Idaigaoka Hasama-machi, Yufu, Oita 8795593, Japan.
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Źródło:
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Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Oct; Vol. 29 (10), pp. 105157. Date of Electronic Publication: 2020 Jul 29.
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Typ publikacji:
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Case Reports; Journal Article; Review
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Język:
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English
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Imprint Name(s):
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Publication: Philadelphia, PA : Saunders
Original Publication: New York, NY : Demos Publications, [1991-
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MeSH Terms:
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Bell Palsy/*complications
Diabetic Angiopathies/*complications
Hypertension/*complications
Intracranial Arteriovenous Malformations/*etiology
Aged ; Bell Palsy/diagnosis ; Cerebrovascular Circulation ; Diabetic Angiopathies/diagnosis ; Hemodynamics ; Humans ; Hypertension/diagnosis ; Intracranial Arteriovenous Malformations/diagnostic imaging ; Intracranial Arteriovenous Malformations/physiopathology ; Intracranial Arteriovenous Malformations/surgery ; Male ; Middle Aged ; Recurrence ; Risk Factors ; Treatment Outcome
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Contributed Indexing:
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Keywords: Aberrant vasculogenesis; Acquired lesion; Angiogenesis; De novo arteriovenous malformations; Second hit
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Entry Date(s):
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Date Created: 20200911 Date Completed: 20201109 Latest Revision: 20201109
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Update Code:
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20240105
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DOI:
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10.1016/j.jstrokecerebrovasdis.2020.105157
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PMID:
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32912502
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Cerebral arteriovenous malformations (AVMs) are generally attributed to congenital lesions that arise from aberrant vasculogenesis between the fourth and eighth weeks of embryonic life. However, this dogma has been challenged by several recent observations, one of which is de novo formation of AVMs. Forty cases of de novo AVMs were published between 2000 and 2019, all of which involved a history of intracranial insult, such as vascular abnormalities or nonvascular conditions, prior to AVM diagnosis. We hereby present two unique operative cases of ruptured de novo AVMs in older adult patients. Case 1 is novel in the sense that the patient did not experience any kind of environmental trigger ("second hit") such as a previous intracranial insult, while Case 2 serves as the second report of a de novo AVM patient with a medical history of Bell's palsy. Although the exact mechanisms of AVM formation remain to be elucidated, it is likely to be a multifactorial process related to environmental and hemodynamic factors.
Competing Interests: Declaration of Competing Interest The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.
(Copyright © 2020 Elsevier Inc. All rights reserved.)