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Tytuł:
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Tacrolimus ointment in the treatment of hormone-dependent dermatitis: A protocol of systematic review.
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Autorzy:
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Li M; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu.
Tan W; Guanghan People's Hospital of Sichuan Province, Deyang, China.
Du J; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu.
Wang Q; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu.
Wang L; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu.
Lei M; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu.
Hao PS; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu.
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Źródło:
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Medicine [Medicine (Baltimore)] 2020 Sep 11; Vol. 99 (37), pp. e22159.
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Typ publikacji:
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Journal Article; Systematic Review
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Język:
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English
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Imprint Name(s):
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Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
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MeSH Terms:
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Adrenal Cortex Hormones/*adverse effects
Calcineurin Inhibitors/*therapeutic use
Drug Eruptions/*drug therapy
Drug Eruptions/*etiology
Tacrolimus/*therapeutic use
Administration, Cutaneous ; Adrenal Cortex Hormones/administration & dosage ; Calcineurin Inhibitors/administration & dosage ; Humans ; Ointments ; Randomized Controlled Trials as Topic ; Research Design ; Tacrolimus/administration & dosage
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References:
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Pediatr Allergy Immunol. 2018 May;29(3):233-238. (PMID: 29205511)
J Am Acad Dermatol. 2015 Mar;72(3):541-549.e2. (PMID: 25592622)
J Dermatol. 2015 Jul;42(7):697-702. (PMID: 25875502)
J Formos Med Assoc. 2015 May;114(5):407-14. (PMID: 23685085)
Curr Drug Metab. 2018;19(4):342-350. (PMID: 29298646)
J Invest Dermatol. 2009 Feb;129(2):375-82. (PMID: 18704103)
Dermatology. 2015;231(1):41-9. (PMID: 26043855)
Am J Clin Dermatol. 2014 Apr;15(2):101-13. (PMID: 24623018)
Endocrinology. 2008 Mar;149(3):1377-88. (PMID: 18039792)
Pediatr Dermatol. 2015 May-Jun;32(3):333-6. (PMID: 25847356)
Dermatitis. 2020 May-Jun;31(3):169-177. (PMID: 32355092)
J Dermatol. 2018 Aug;45(8):936-942. (PMID: 29927498)
Syst Rev. 2015 Jan 01;4:1. (PMID: 25554246)
J Am Acad Dermatol. 2011 Jan;64(1):49-52. (PMID: 20943287)
Br J Dermatol. 2014 Apr;170(4):914-21. (PMID: 24328907)
Ann Dermatol. 2018 Apr;30(2):173-178. (PMID: 29606814)
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Substance Nomenclature:
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0 (Adrenal Cortex Hormones)
0 (Calcineurin Inhibitors)
0 (Ointments)
WM0HAQ4WNM (Tacrolimus)
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Entry Date(s):
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Date Created: 20200914 Date Completed: 20200930 Latest Revision: 20221005
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Update Code:
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20240105
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PubMed Central ID:
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PMC7489724
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DOI:
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10.1097/MD.0000000000022159
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PMID:
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32925777
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Background: Long-term use of corticosteroid ointment for external using or skin management products and cosmetics containing corticosteroid will produce a hormone-dependent effect on facial skin and destroy the barrier function of the skin. It is easy to cause repeated attacks of facial skin inflammation after drug withdrawal because corticosteroid hormones can cause the expression of inflammatory factors in the body, which has a serious impact on patients. The general treatment method is to stop using hormone drugs for psychotherapy and inform patients of the basic knowledge of hormone-dependent dermatitis and daily facial care, but the effect is not good. At present, non-steroidal ointment tacrolimus (a calcineurin inhibitor) is widely used in the treatment of hormone-dependent dermatitis. Tacrolimus ointment is effective for corticosteroid-dependent dermatitis, but adverse events can also occur.
Methods: We plan to searched all randomized controlled trials (RCTs) fortacrolimus ointment therapy of hormone-dependent dermatitis in: MEDLINE, PubMed, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), Springer and Web of Science, China Biomedical Literature Database (CBM), China Science Journal Database (VIP database) and Wanfang Database, China National Knowledge Infrastructure (CNKI), without the limitation of publication status and language until September 1, 2020. The systematic review will also search will also search for identify publications, meeting minutes, and grey literature (including unpublished meeting articles).
Discussion: The systematic review mainly to access the safety and efficacy of tacrolimus ointment for hormone-dependent dermatitis (facial corticosteroid addiction dermatitis and facial steroid dermatitis). The results of our research will facilitate evidence-based management of patients with facial corticosteroid-dependent dermatitis and provide clinical advice on their treatment options.
Registration: PROSPERO CRD42020171813.
