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Tytuł pozycji:

Bronchiectasis with secondary pulmonary infection in a child: A case report.

Tytuł:
Bronchiectasis with secondary pulmonary infection in a child: A case report.
Autorzy:
Zhu T; Department of Respiratory Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Gu H; Department of Respiratory Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Vinturache A; Department of Obstetrics and Gynecology, Queen Elizabeth II Hospital, Alberta, Canada.
Ding G; Department of Respiratory Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Lu M; Department of Respiratory Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Źródło:
Medicine [Medicine (Baltimore)] 2020 Sep 25; Vol. 99 (39), pp. e22475.
Typ publikacji:
Case Reports; Journal Article
Język:
English
Imprint Name(s):
Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
MeSH Terms:
Bronchiectasis/*complications
Pseudomonas Infections/*complications
Pseudomonas aeruginosa/*isolation & purification
Anti-Bacterial Agents/administration & dosage ; Bronchiectasis/microbiology ; Child ; Female ; Humans ; Pseudomonas Infections/drug therapy
References:
Med J Aust. 2015 Jan 19;202(1):21-3. (PMID: 25588439)
Zhonghua Er Ke Za Zhi. 2009 Jul;47(7):493-8. (PMID: 19951508)
Ital J Pediatr. 2017 Dec 29;43(1):117. (PMID: 29284507)
BMC Pediatr. 2014 Dec 10;14:4. (PMID: 25492164)
Nat Rev Dis Primers. 2018 Nov 15;4(1):45. (PMID: 30442957)
Cochrane Database Syst Rev. 2015 Aug 13;(8):CD001392. (PMID: 26270620)
Ann Am Thorac Soc. 2016 May;13(5):609-16. (PMID: 26882271)
Front Pediatr. 2017 Feb 20;5:27. (PMID: 28265556)
Cochrane Database Syst Rev. 2009 Apr 15;(2):CD006316. (PMID: 19370631)
Cochrane Database Syst Rev. 2013 May 31;(5):CD008351. (PMID: 23728674)
Lancet. 2018 Sep 8;392(10150):866-879. (PMID: 30215382)
Pediatr Pulmonol. 2016 May;51(5):450-69. (PMID: 26840008)
Substance Nomenclature:
0 (Anti-Bacterial Agents)
Entry Date(s):
Date Created: 20200929 Date Completed: 20201013 Latest Revision: 20221005
Update Code:
20240105
PubMed Central ID:
PMC7523858
DOI:
10.1097/MD.0000000000022475
PMID:
32991486
Czasopismo naukowe
Rationale: Although bronchiectasis is conventionally considered a chronic pulmonary disease of adulthood, knowledge of pediatric bronchiectasis not related to cystic fibrosis started to emerge. Limited information in this field is available and the management is based on expert opinion.
Patient Concerns: An 8-year-old girl admitted for 7 days history of wet cough, purulent fetid sputum, shortness of breath and low-grade fever. The wet cough has presented for the past 4 years, during which she had frequent hospitalization for recurrent lower respiratory tract infections.
Diagnosis: Chest high-resolution computerized tomography revealed diffuse bronchial dilations accompanied by inflammation in the bilateral lung fields. Microbiologic investigation for bronchoalveolar lavage fluid was positive for Pseudomonas aeruginosa.
Interventions: With a working diagnosis of bronchiectasis with secondary pulmonary infection, sensitive cefoperazone-sulbactam was administrated for 14 days with gradual improvement of clinical symptoms. Bronchoscopy washing substantially soothed the symptoms, reducing the cough and sputum volumes.
Outcomes: The child was discharged after 14 days, and treated on long-term prophylactic antibiotic use (amoxicillin-clavulanic acid, 20 mg/kg/d, ≥ 4 weeks).
Lessons: Although bronchiectasisis are condition in childhood, the diagnosis is suspected in children with persistent wet or productive cough, and should be confirmed by a chest high-resolution computerized tomography scan. Antibiotics and airway clearance techniques represent the milestones of bronchiectasis management although there are only a few guidelines in children.

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