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Tytuł:
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CD3-CD20-positive nodal lymphoma with cross-lineage rearrangement in a dog.
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Autorzy:
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Nicoletti A; School of Agriculture and Veterinary Medicine, University of Turin, Grugliasco, Turin, Italy.
Aresu L; School of Agriculture and Veterinary Medicine, University of Turin, Grugliasco, Turin, Italy.
Marino M; Laboratorio La Vallonea, Passirana di Rho, Milano, Italy.
Massaro M; Laboratorio La Vallonea, Passirana di Rho, Milano, Italy.
Martignani E; School of Agriculture and Veterinary Medicine, University of Turin, Grugliasco, Turin, Italy.
Caporali E; Clinica Veterinaria San Rocco, Foiana della Chiana, Arezzo, Italy.
Capuccini S; Clinica Veterinaria San Rocco, Foiana della Chiana, Arezzo, Italy.
Bonfanti U; Laboratorio La Vallonea, Passirana di Rho, Milano, Italy.
Gola C; School of Agriculture and Veterinary Medicine, University of Turin, Grugliasco, Turin, Italy.
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Źródło:
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Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest] 2020 Nov; Vol. 32 (6), pp. 964-967. Date of Electronic Publication: 2020 Oct 01.
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Typ publikacji:
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Case Reports; Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: 2011-: Thousand Oaks, CA : Sage
Original Publication: 1989-2004 : Columbia, MO : American Association of Veterinary Laboratory Diagnosticians
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MeSH Terms:
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Gene Rearrangement*
Antigens, CD20/*genetics
CD3 Complex/*genetics
Dog Diseases/*diagnosis
Dog Diseases/*genetics
Lymphoma, Large B-Cell, Diffuse/*veterinary
Animals ; Antigens, CD20/metabolism ; CD3 Complex/metabolism ; Dog Diseases/physiopathology ; Dogs ; Fluorescent Antibody Technique/veterinary ; Immunohistochemistry ; Lymph Nodes/pathology ; Lymphoma, Large B-Cell, Diffuse/diagnosis ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/physiopathology ; Male
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References:
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Front Vet Sci. 2017 May 31;4:76. (PMID: 28620611)
J Vet Diagn Invest. 2018 Sep;30(5):779-783. (PMID: 30129396)
Vet Comp Oncol. 2017 Sep;15(3):1101-1114. (PMID: 27402031)
J Mol Diagn. 2006 Sep;8(4):426-9; quiz 526-7. (PMID: 16931581)
J Immunol. 2016 Aug 15;197(4):1111-7. (PMID: 27412413)
J Mol Diagn. 2006 Sep;8(4):466-75; quiz 527. (PMID: 16931587)
Vet Pathol. 2016 May;53(3):563-6. (PMID: 26354309)
Vet Pathol. 2011 Jan;48(1):198-211. (PMID: 20861499)
Front Immunol. 2018 Nov 13;9:2426. (PMID: 30483245)
Vet Comp Oncol. 2015 Dec;13(4):348-62. (PMID: 23782432)
Vet Pathol. 2018 Mar;55(2):241-244. (PMID: 29343197)
Crit Rev Oncol Hematol. 2011 Sep;79(3):330-43. (PMID: 21273093)
BMC Vet Res. 2019 Nov 16;15(1):413. (PMID: 31733649)
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Contributed Indexing:
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Keywords: CD3/CD20 positive; PARR; canine nodal lymphoma; dogs
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Substance Nomenclature:
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0 (Antigens, CD20)
0 (CD3 Complex)
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Entry Date(s):
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Date Created: 20201001 Date Completed: 20210119 Latest Revision: 20211002
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Update Code:
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20240105
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PubMed Central ID:
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PMC7649537
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DOI:
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10.1177/1040638720963132
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PMID:
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33000710
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A 7-y-old mixed-breed male dog was presented with a history of generalized lymphadenopathy. Fine-needle aspirates of the enlarged peripheral lymph nodes were suggestive of lymphoma. Histologic examination of a retromandibular lymph node was suggestive of high-grade, medium large-cell lymphoma. Immunohistochemistry revealed concurrent expression of CD3 and CD20. The co-localization of the 2 antigens was confirmed by immunofluorescence. PCR for antigen receptor gene rearrangements (PARR) detected clonal rearrangements for both T-cell receptor gamma and B-cell receptor. The final diagnosis was CD3-CD20-positive anaplastic lymphoma with cross-lineage rearrangement.