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Tytuł pozycji:

Functionalized Scaffold and Barrier Membrane with Anti-BMP-2 Monoclonal Antibodies for Alveolar Ridge Preservation in a Canine Model.

Tytuł :
Functionalized Scaffold and Barrier Membrane with Anti-BMP-2 Monoclonal Antibodies for Alveolar Ridge Preservation in a Canine Model.
Autorzy :
Min S; Department of Periodontics and Dental Hygiene, University of Texas Health Science Center at Houston, Houston, TX, USA.
Kim T; Department of Periodontics, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA.
Kim O; Department of Periodontology, Dental Research Institute, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea.
Goncalo C; Department of Periodontology, Implantology Institute, Lisbon, Portugal.
Utsunomiya T; Department of Pathology, School of Dentistry, Nihon University at Matsudo, Chiba, Japan.
Matsumoto T; Division of Diagnostic Pathology, Nihon University Hospital School of Dentistry at Matsudo, Chiba, Japan.
Kuyama K; Department of Pathology, School of Dentistry, Nihon University at Matsudo, Chiba, Japan.
Angelov N; Department of Periodontics and Dental Hygiene, University of Texas Health Science Center at Houston, Houston, TX, USA.
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Źródło :
BioMed research international [Biomed Res Int] 2020 Sep 22; Vol. 2020, pp. 6153724. Date of Electronic Publication: 2020 Sep 22 (Print Publication: 2020).
Typ publikacji :
Journal Article
Język :
English
Imprint Name(s) :
Original Publication: New York, NY : Hindawi Pub. Co.
MeSH Terms :
Alveolar Process/*pathology
Antibodies, Monoclonal/*pharmacology
Bone Morphogenetic Protein 2/*immunology
Tissue Scaffolds/*chemistry
Alveolar Process/drug effects ; Anatomic Landmarks ; Animals ; Bicuspid/diagnostic imaging ; Bicuspid/pathology ; Cone-Beam Computed Tomography ; Disease Models, Animal ; Dogs ; Mandible/diagnostic imaging ; Mandible/pathology ; Membranes ; Organ Size/drug effects
References :
Clin Oral Implants Res. 2012 Feb;23 Suppl 5:1-21. (PMID: 22211303)
Spine J. 2016 Oct;16(10):1208-1213. (PMID: 27343729)
Int J Oral Maxillofac Implants. 2016 Mar-Apr;31(2):288-92. (PMID: 27004275)
J Clin Periodontol. 2005 Feb;32(2):212-8. (PMID: 15691354)
Medicine (Baltimore). 2017 Mar;96(10):e6267. (PMID: 28272237)
J Craniofac Surg. 2016 May;27(3):805-9. (PMID: 27092911)
Clin Oral Implants Res. 2016 Jul;27(7):859-66. (PMID: 26498407)
Int J Periodontics Restorative Dent. 2014 Mar-Apr;34(2):211-7. (PMID: 24600657)
J Periodontol. 2014 Apr;85(4):525-35. (PMID: 23826643)
Int J Oral Maxillofac Implants. 2014 Jan-Feb;29(1):141-51. (PMID: 24451865)
Spine (Phila Pa 1976). 2016 Sep 15;41(18):E1115-23. (PMID: 27031772)
Clin Oral Implants Res. 2016 Jun;27(6):640-9. (PMID: 26521754)
J Prosthet Dent. 1967 Jan;17(1):21-7. (PMID: 5224784)
J Clin Periodontol. 2017 Feb;44(2):204-214. (PMID: 27883211)
Int J Oral Maxillofac Implants. 2002 Mar-Apr;17(2):249-57. (PMID: 11958408)
Eur J Oral Implantol. 2010 Summer;3(2):121-34. (PMID: 20623037)
J Dent Res. 2015 Sep;94(9 Suppl):187S-93S. (PMID: 26130259)
J Bone Miner Res. 2013 Jan;28(1):2-17. (PMID: 23197339)
J Periodontol. 2003 Jul;74(7):990-9. (PMID: 12931761)
Compend Contin Educ Dent. 2011 Mar;32(2):18, 20-7; quiz 28, 40. (PMID: 21473297)
Clin Orthop Relat Res. 2015 Sep;473(9):2885-97. (PMID: 25917422)
Biomed Res Int. 2017;2017:8094152. (PMID: 28401163)
Biomed Res Int. 2014;2014:940860. (PMID: 25147826)
Injury. 2009 Dec;40 Suppl 3:S67-76. (PMID: 20082795)
Clin Orthop Relat Res. 2015 Jul;473(7):2383-93. (PMID: 25822454)
J Hand Surg Am. 2016 May;41(5):602-8. (PMID: 27013317)
J Oral Maxillofac Surg. 2014 Mar;72(3):456-62. (PMID: 24342581)
Clin Oral Implants Res. 2013 Mar;24(3):255-61. (PMID: 22882634)
J Bone Joint Surg Am. 2006 Jul;88(7):1431-41. (PMID: 16818967)
Int J Periodontics Restorative Dent. 2012 Aug;32(4):421-30. (PMID: 22577648)
Medicine (Baltimore). 2017 Jul;96(27):e7413. (PMID: 28682898)
J Biomater Appl. 2017 Oct;32(4):425-432. (PMID: 28992803)
Int J Biol Sci. 2012;8(2):272-88. (PMID: 22298955)
Clin Oral Implants Res. 2017 Nov;28(11):e252-e261. (PMID: 28422326)
Biomaterials. 2013 Dec;34(38):10191-8. (PMID: 24055525)
Clin Oral Investig. 2015 Apr;19(3):589-600. (PMID: 24998770)
Tissue Eng Part A. 2015 Jul;21(13-14):2013-24. (PMID: 25813520)
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000 Nov;90(5):581-6. (PMID: 11077380)
Clin Oral Implants Res. 2016 Jan;27(1):97-105. (PMID: 25655480)
Tissue Eng Part A. 2011 Dec;17(23-24):2911-8. (PMID: 21870943)
J Biomed Mater Res B Appl Biomater. 2016 Oct;104(7):1465-73. (PMID: 26252572)
Biomed Res Int. 2015;2015:628769. (PMID: 25705677)
Clin Oral Implants Res. 2011 Aug;22(8):779-88. (PMID: 21091540)
Int J Periodontics Restorative Dent. 2012 Oct;32(5):543-52. (PMID: 22754902)
J Mater Sci Mater Med. 2016 Dec;27(12):184. (PMID: 27787808)
Spine (Phila Pa 1976). 2015 Dec;40(23):1862-71. (PMID: 26274524)
Int J Oral Maxillofac Surg. 2013 Dec;42(12):1522-8. (PMID: 23845297)
Compend Contin Educ Dent. 1998 Dec;19(12):1256-8, 1260, 1262-4. (PMID: 10202461)
Int J Periodontics Restorative Dent. 2004 Dec;24(6):545-53. (PMID: 15626317)
J Periodontol. 1994 Dec;65(12):1128-33. (PMID: 7877084)
Biomaterials. 2013 Sep;34(28):6572-9. (PMID: 23773817)
JAMA. 2009 Jul 1;302(1):58-66. (PMID: 19567440)
Clin Oral Implants Res. 2016 Jun;27(6):631-9. (PMID: 26518980)
Acta Histochem. 2015 Apr;117(3):288-96. (PMID: 25825118)
Spine J. 2017 Sep;17(9):1247-1254. (PMID: 28456674)
Aust Dent J. 1969 Aug;14(4):241-4. (PMID: 5259350)
Clin Oral Implants Res. 2016 Sep;27(9):1144-51. (PMID: 26660705)
Clin Oral Implants Res. 2011 Oct;22(10):1168-1171. (PMID: 21320168)
J Clin Periodontol. 2013 Jan;40(1):90-8. (PMID: 23163915)
Clin Oral Implants Res. 2012 Feb;23 Suppl 5:80-2. (PMID: 22211307)
Tissue Eng Part A. 2013 May;19(9-10):1165-74. (PMID: 23190409)
Spine J. 2008 May-Jun;8(3):419-25. (PMID: 18375186)
Clin Oral Implants Res. 2012 Feb;23 Suppl 5:22-38. (PMID: 22211304)
Orthop Traumatol Surg Res. 2016 Apr;102(2):255-6. (PMID: 26947733)
Clin Oral Implants Res. 2011 Jan;22(1):9-13. (PMID: 21091539)
Int J Periodontics Restorative Dent. 2003 Aug;23(4):313-23. (PMID: 12956475)
J Clin Periodontol. 2017 Feb;44(2):225-234. (PMID: 27891638)
Clin Oral Implants Res. 2003 Apr;14(2):137-43. (PMID: 12656871)
J Neurosurg Spine. 2016 Mar;24(3):457-75. (PMID: 26613283)
Neurosurg Focus. 2015 Oct;39(4):E13. (PMID: 26424337)
Substance Nomenclature :
0 (Antibodies, Monoclonal)
0 (Bone Morphogenetic Protein 2)
Entry Date(s) :
Date Created: 20201008 Date Completed: 20210429 Latest Revision: 20210429
Update Code :
20210506
PubMed Central ID :
PMC7530509
DOI :
10.1155/2020/6153724
PMID :
33029518
Czasopismo naukowe
Introduction: The aim of this study was to investigate the ability of anti-bone morphogenetic protein 2 monoclonal antibody (anti-BMP-2 mAb) to functionalize scaffolds to mediate bone regeneration in a canine model.
Materials and Methods: The mandibular right premolar 4 (PM4) was extracted in eight beagle dogs and grafted with anti-BMP-2 mAb+anorganic bovine bone mineral with 10% collagen (ABBM-C) and porcine bilayer native collagen membrane (CM). The ABBM-C and CM were functionalized with either anti-BMP-2 mAb (test group) or an isotype matched control mAb (control group). Animals were euthanized at 12 weeks for radiographic, histologic, and histomorphometric analyses. Outcomes were compared between groups.
Results: 3D imaging using cone beam computed tomography (CBCT) revealed that sites treated with ABBM-C and CM functionalized with anti-BMP-2 mAb exhibited significantly more remaining bone width near the alveolar crest, as well as buccal bone height, compared with control groups. Histologic and histomorphometric analyses demonstrated that in anti-BMP-2 mAb-treated sites, total tissue volume was significantly higher in the coronal part of the alveolar bone crest compared with control sites. In anti-BMP-2 mAb-treated sites, bone formation was observed under the barrier membrane.
Conclusion: Functionalization of the ABBM-C scaffold and CM appeared to have led to bone formation within healing alveolar bone sockets.
(Copyright © 2020 Seiko Min et al.)
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