Bioglass could increase cell membrane fluidity with ion products to develop its bioactivity.

Tytuł:: Bioglass could increase cell membrane fluidity with ion products to develop its bioactivity.
Autorzy:: Yan L; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Li H; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Xia W; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Źródło:: Cell proliferation [Cell Prolif] 2020 Nov; Vol. 53 (11), pp. e12906. Date of Electronic Publication: 2020 Oct 11.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Original Publication: [Oxford, England] : Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications, 1991-
MeSH Terms:: Membrane Fluidity*
Biocompatible Materials/*metabolism
Ceramics/*metabolism
Human Umbilical Vein Endothelial Cells/*cytology
Mesenchymal Stem Cells/*cytology
Cations, Monovalent/metabolism ; Cell Differentiation ; Cell Line ; Cell Movement ; Cells, Cultured ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Ions/metabolism ; Mesenchymal Stem Cells/metabolism ; Silicon/metabolism
References:: PLoS One. 2016 Jun 30;11(6):e0158313. (PMID: 27362860)
Cell Stress Chaperones. 2014 Nov;19(6):877-86. (PMID: 24789271)
J Investig Clin Dent. 2017 May;8(2):. (PMID: 26434562)
Hepatology. 2008 Jan;47(1):59-70. (PMID: 18038449)
Acta Biomater. 2017 Sep 1;59:2-11. (PMID: 28676434)
Acta Biomater. 2011 Jun;7(6):2355-73. (PMID: 21421084)
Biophys J. 1993 Jun;64(6):1766-80. (PMID: 8369407)
Tissue Eng. 2005 May-Jun;11(5-6):768-77. (PMID: 15998217)
Mater Sci Eng C Mater Biol Appl. 2016 Dec 1;69:1137-46. (PMID: 27612811)
Materials (Basel). 2010 Jul 06;3(7):3867-3910. (PMID: 28883315)
Adv Biol Regul. 2015 Jan;57:130-46. (PMID: 25465296)
Methods Mol Biol. 2017;1520:159-174. (PMID: 27873252)
Chem Sci. 2016 Jan 1;7(1):489-498. (PMID: 28791102)
Prog Lipid Res. 2015 Jul;59:38-53. (PMID: 25969421)
J Tissue Eng Regen Med. 2018 Mar;12(3):e1609-e1622. (PMID: 29024443)
F1000Res. 2019 Jun 5;8:. (PMID: 31231509)
Adv Sci (Weinh). 2018 Nov 08;6(1):1801260. (PMID: 30643722)
Oncol Rep. 2001 May-Jun;8(3):527-32. (PMID: 11295074)
Biochim Biophys Acta Biomembr. 2018 Aug;1860(8):1571-1579. (PMID: 29806993)
ACS Appl Mater Interfaces. 2016 Jan 13;8(1):703-15. (PMID: 26684719)
J Biol Chem. 2004 Aug 27;279(35):36540-5. (PMID: 15231827)
ACS Appl Mater Interfaces. 2018 Sep 12;10(36):30103-30114. (PMID: 30113159)
Cell Prolif. 2020 Nov;53(11):e12906. (PMID: 33043500)
Protein Cell. 2016 Apr;7(4):281-290. (PMID: 26983852)
Acta Biomater. 2015 Jul;21:190-203. (PMID: 25900445)
Nano Lett. 2016 May 11;16(5):3042-50. (PMID: 27070195)
Sci Rep. 2018 Nov 19;8(1):17022. (PMID: 30451899)
PLoS One. 2011;6(12):e28818. (PMID: 22174906)
Front Oral Biol. 2015;17:22-32. (PMID: 26201273)
Proc Natl Acad Sci U S A. 1994 Aug 16;91(17):8234-8. (PMID: 8058786)
Biochim Biophys Acta. 2014 May;1838(5):1235-46. (PMID: 24472512)
Adv Exp Med Biol. 2018;1066:265-277. (PMID: 30030831)
Cell. 2019 May 2;177(4):806-819. (PMID: 31051105)
Trends Biotechnol. 2018 Apr;36(4):430-444. (PMID: 29397989)
Tissue Eng Part A. 2015 Jan;21(1-2):382-9. (PMID: 25167933)
Adv Sci (Weinh). 2018 Sep 30;5(11):1800776. (PMID: 30479923)
J Cell Sci. 2019 May 31;132(11):. (PMID: 31152052)
BMC Cell Biol. 2015 Mar 13;16:9. (PMID: 25887471)
Biophys J. 2018 Oct 2;115(7):1146-1155. (PMID: 30219286)
Chem Phys Lipids. 2003 Jan;122(1-2):159-63. (PMID: 12598047)
Methods Mol Biol. 2017;1636:417-453. (PMID: 28730495)
Acta Biomater. 2015 Feb;13:1-15. (PMID: 25462853)
J Biomed Mater Res. 1993 Nov;27(11):1367-81. (PMID: 8262999)
Biomaterials. 2016 Apr;84:64-75. (PMID: 26821121)
Acta Biomater. 2017 Jun;55:249-261. (PMID: 28377306)
Biochemistry. 2019 Nov 26;58(47):4761-4773. (PMID: 31508939)
J Cell Mol Med. 2008 Jun;12(3):829-75. (PMID: 18266954)
Front Bioeng Biotechnol. 2015 Nov 30;3:194. (PMID: 26649290)
Grant Information:: 31771024 National Natural Science Foundation of China; 31971274 National Natural Science Foundation of China; 81773115 National Natural Science Foundation of China; YG2017MS52 Shanghai Jiao Tong University
Contributed Indexing:: Keywords: Bioglass; cell activity; membrane fluidity; silicon
Substance Nomenclature:: 0 (Biocompatible Materials)
0 (Bioglass)
0 (Cations, Monovalent)
0 (Ions)
Z4152N8IUI (Silicon)
Entry Date(s):: Date Created: 20201012 Date Completed: 20201120 Latest Revision: 20201120
Update Code:: 20240105
PubMed Central ID:: PMC7653244
DOI:: 10.1111/cpr.12906
PMID:: 33043500
: Czasopismo naukowe

Pełny tekst

Objectives: Silicate bioactive glass (BG) has been widely demonstrated to stimulate both of the hard and soft tissue regeneration, in which ion products released from BG play important roles. However, the mechanism by which ion products act on cells on cells is unclear.
Materials and Methods: Human umbilical vein endothelial cells and human bone marrow stromal cells were used in this study. Fluorescence recovery after photobleaching and generalized polarization was used to characterize changes in cell membrane fluidity. Migration, differentiation and apoptosis experiments were carried out. RNA and protein chip were detected. The signal cascade is simulated to evaluate the effect of increased cell membrane fluidity on signal transduction.
Results: We have demonstrated that ion products released from BG could effectively enhance cell membrane fluidity in a direct and physical way, and Si ions may play a major role. Bioactivities of BG ion products on cells, such as migration and differentiation, were regulated by membrane fluidity. Furthermore, we have proved that BG ion products could promote apoptosis of injured cells based on our conclusion that BG ion products increased membrane fluidity.
Conclusions: This study proved that BG ion products could develop its bioactivity on cells by directly enhancing cell membrane fluidity and subsequently affected cell behaviours, which may provide an explanation for the general bioactivities of silicate material.
(© 2020 The Authors. Cell Proliferation Published by John Wiley & Sons Ltd.)

Zaloguj się, aby uzyskać dostęp do pełnego tekstu.

Informacja