A systematic review of early adoption of implementation science for HIV prevention or treatment in the United States.

Tytuł:: A systematic review of early adoption of implementation science for HIV prevention or treatment in the United States.
Autorzy:: Shangani S; College of Health Sciences, Department of Community & Environmental Health, Old Dominion University, Norfolk, Virginia.
Bhaskar N; Department of Behavioral and Social Sciences, School of Public Health, Brown University, Providence, Rhode Island.
Richmond N; Department of Behavioral and Social Sciences, School of Public Health, Brown University, Providence, Rhode Island.
Operario D; Department of Behavioral and Social Sciences, School of Public Health, Brown University, Providence, Rhode Island.
van den Berg JJ; Department of Behavioral and Social Sciences, School of Public Health, Brown University, Providence, Rhode Island.; Department of Epidemiology, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, USA.
Źródło:: AIDS (London, England) [AIDS] 2021 Feb 02; Vol. 35 (2), pp. 177-191.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Systematic Review
Język:: English
Imprint Name(s):: Publication: 1998- : London, England : Lippincott Williams & Wilkins
Original Publication: London : Gower Academic Journals, c1987-
MeSH Terms:: HIV Infections*/prevention & control
Implementation Science*
Humans ; United States
References:: Fauci AS, Redfield RR, Sigounas G, Weahkee MD, Giroir BP. Ending the HIV epidemic: a plan for the United States . JAMA 2019; 321:844–845.
The US Department of Health Services & Human Services. Ending the HIV epidemic: a plan for America. Washington, DC: US Department of Health Services & Human Services, 2019. Available at files.hiv.gov/s3fs-public/endingthe-hiv-epidemic-flyer.pdf. [Accessed 12 August 2019].
Department of Health and Human Services, CDC. HIV surveillance reports. Atlanta, GA: CDC, 2017. Available at https://www.cdc.gov/nchhstp/atlas/index.htm . [Accessed 4 February 2019].
CDC. Basic HIV statistics. Atlanta, GA: CDC; 2019, Available at https://www.cdc.gov/hiv/basics/statistics.html . [Accessed 21–20 July 2020].
Linley L, Johnson AS, Song R, Wu B, Hu S, Singhs S, et al. Estimated HIV incidence and prevalence in the United States 2010–2015 . Atlanta, GA: CDC; 2018.
UNAIDS. 90–90–90 An ambitious treatment target to help end the AIDS epidemic. Geneva, Switzerland: UNAIDS; 2014. Available at http://www.unaids.org/en/resources/documents/2017/90-90-90 . [Accessed 13 July 2018].
UNAIDS. Fast-track: ending the AIDS epidemic by 2030. Geneva, Switzerland: UNAIDS; 2015.
Jones J, Sullivan PS, Curran JW. Progress in the HIV epidemic: identifying goals and measuring success . PLoS Med 2019; 16:e1002729.
Smith JD, Li DH, Hirschhorn LR, Gallo C, McNulty M, Phillips G 2nd, et al. Landscape of HIV implementation research funded by the National Institutes of Health: a mapping review of project abstracts . AIDS Behav 2020; 24:1903–1911.
Kemp CG, Velloza J. Implementation of eHealth interventions across the HIV care cascade: a review of recent research . Curr HIV/AIDS Rep 2018; 15:403–413.
Aibana O, Franke MF, Huang CC, Galea JT, Calderon R, Zhang Z, et al. Vitamin E status is inversely associated with risk of incident tuberculosis disease among household contacts . J Nutr 2018; 148:56–62.
Schackman BR. Implementation science for the prevention and treatment of HIV/AIDS . J Acquir Immune Defic Syndr 2010; 55: (Suppl 1): S27–S31.
Proctor E, Silmere H, Raghavan R, Hovmand P, Aarons G, Bunger A, et al. Outcomes for implementation research: conceptual distinctions, measurement challenges, and research agenda . Adm Policy Ment Health 2011; 38:65–76.
Tetroe J. Knowledge translation at the Canadian Institutes of Health Research: a primer . Focus Technical Brief 2007; 18:1–8.
Damschroder LJ, Aron DC, Keith RE, Kirsh SR, Alexander JA, Lowery JC. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science . Implement Sci 2009; 4:50.
Glasgow RE, Vogt TM, Boles SM. Evaluating the public health impact of health promotion interventions: the RE-AIM framework . Am J Public Health 1999; 89:1322–1327.
Curran GM, Bauer M, Mittman B, Pyne JM, Stetler C. Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact . Med Care 2012; 50:217–226.
Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement . Ann Intern Med 2009; 151:264–269. w64.
Henry Kaiser Family Foundation. US federal funding for HIV/AIDS: trends over time . San Francisco, CA: Henry J. Kaiser Foundation; 2019.
Odeny TA, Padian N, Doherty MC, Baral S, Beyrer C, Ford N, Geng EH. Definitions of implementation science in HIV/AIDS . Lancet HIV 2015; 2:e178–e180.
Montgomery P, Underhill K, Gardner F, Operario D, Mayo-Wilson E. The Oxford Implementation Index: a new tool for incorporating implementation data into systematic reviews and meta-analyses . J Clin Epidemiol 2013; 66:874–882.
Hoffmann TC, Glasziou PP, Boutron I, Milne R, Perera R, Moher D, et al. Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide . BMJ 2014; 348:g1687.
Landovitz RJ, Beymer M, Kofron R, Amico KR, Psaros C, Bushman LET-AL>. Plasma tenofovir levels to support adherence to TDF/FTC preexposure prophylaxis for HIV prevention in MSM in Los Angeles, California . J Acquir Immune Defic Syndr 2017; 76:501–511.
McGowan I, Cranston RD, Mayer KH, Febo I, Duffill K, Siegel A, et al. Project gel a randomized rectal microbicide safety and acceptability study in young men and transgender women . PLoS One 2016; 11:e0158310.
Giguere R, Dolezal C, Bauermeister JA, Frasca T, Valladares J, Febo I, et al. Influence of partner type on acceptability and likelihood of use of a rectal microbicide among young men who have sex with men in the United States and Puerto Rico . J Sex Res 2016; 53:633–641.
Operario D, Gamarel KE, Iwamoto M, Suzuki S, Suico S, Darbes L, Nemoto T. Couples-focused prevention program to reduce HIV risk among transgender women and their primary male partners: feasibility and promise of the couples HIV intervention program . AIDS Behav 2017; 21:2452–2463.
Swendeman D, Ramanathan N, Baetscher L, Medich M, Scheffler A, Comulada WS, Estrin D. Smartphone self-monitoring to support self-management among people living with HIV: perceived benefits and theory of change from a mixed-methods randomized pilot study . J Acquir Immune Defic Syndr 2015; 69: (Suppl 1): S80–S91.
Bauermeister J, Giguere R, Leu CS, Febo I, Cranston R, Mayer K, Carballo-Diéguez A. Interactive voice response system: data considerations and lessons learned during a rectal microbicide placebo adherence trial for young men who have sex with men . J Med Internet Res 2017; 19:e207.
Arnold EA, Operario D, Cornwell S, Benjamin M, Smith CD, Lockett G, Kegeles SM. The development of a counseling-based HIV prevention intervention for African American men who have sex with men and women: the Bruthas project . AIDS Educ Prev 2015; 27:505–521.
Berkley-Patton J, Thompson CB, Moore E, Hawes S, Simon S, Goggin K, et al. An HIV testing intervention in African American churches: pilot study findings . Ann Behav Med 2016; 50:480–485.
Bouris A, Jaffe K, Eavou R, Liao C, Kuhns L, Voisin D, Schneider JA. Project nGage: results of a randomized controlled trial of a dyadic network support intervention to retain young black men who have sex with men in hiv care . AIDS Behav 2017; 21:3618–3629.
Brown LK, Hadley W, Donenberg GR, DiClemente RJ, Lescano C, Lang DM, et al. Project STYLE: a multisite RCT for HIV prevention among youths in mental health treatment . Psychiatr Serv 2014; 65:338–344.
Cordova D, Alers-Rojas F, Mendoza Lua F, Bauermeister J, Nurenberg R, Ovadje L, et al. The usability and acceptability of an adolescent mHealth HIV/STI and drug abuse preventive intervention in primary care . Behav Med 2018; 44:36–47.
Cunningham WE, Ford CL, Kinsler JJ, Seiden D, Andrews L, Nakazono T, Bell DS. Effects of a laboratory health information exchange intervention on antiretroviral therapy use, viral suppression, and racial/ethnic disparities . J Acquir Immune Defic Syndr 2017; 75:290–298.
DiClemente RJ, Wingood GM, Sales JM, Brown JL, Rose ES, Davis TL, et al. Efficacy of a telephone-delivered sexually transmitted infection/human immunodeficiency virus prevention maintenance intervention for adolescents: a randomized clinical trial . JAMA Pediatr 2014; 168:938–946.
Eggman AA, Feaster DJ, Leff JA, Golden MR, Castellon PC, Gooden L, et al. The cost of implementing rapid HIV testing in sexually transmitted disease clinics in the United States . Sex Transm Dis 2014; 41:545–550.
Festinger DS, Dugosh KL, Kurth AE, Metzger DS. Examining the efficacy of a computer facilitated HIV prevention tool in drug court . Drug Alcohol Depend 2016; 162:44–50.
Frye V, Paige MQ, Gordon S, Matthews D, Musgrave G, Kornegay M, et al. Developing a community-level anti-HIV/AIDS stigma and homophobia intervention in new York city: the project CHHANGE model . Eval Program Plann 2017; 63:45–53.
Giguere R, Frasca T, Dolezal C, Febo I, Cranston R, Mayer K, et al. Acceptability of three novel HIV prevention methods among young male and transgender female sex workers in Puerto Rico . AIDS Behav 2016; 20:2192–2202.
Gwadz M, Cleland CM, Applegate E, Belkin M, Gandhi M, Salomon N, et al. Behavioral intervention improves treatment outcomes among HIV-infected individuals who have delayed, declined, or discontinued antiretroviral therapy: a randomized controlled trial of a novel intervention . AIDS Behav 2015; 19:1801–1817.
Hoenigl M, Chaillon A, Mehta SR, Smith DM, Graff-Zivin J, Little SJ, et al. Screening for acute HIV infection in community-based settings: cost-effectiveness and impact on transmissions . J Infect 2016; 73:476–484.
Hosek SG, Lemos D, Hotton AL, Fernandez MI, Telander K, Footer D, Bell M. An HIV intervention tailored for black young men who have sex with men in the House Ball Community . AIDS Care 2015; 27:355–362.
Johnson JE, Peabody ME, Wechsberg WM, Rosen RK, Fernandes K, Zlotnick C. Feasibility of an HIV/STI risk-reduction program for incarcerated women who have experienced interpersonal violence . J Interpers Violence 2015; 30:3244–3266.
Kurth AE, Chhun N, Cleland CM, Crespo-Fierro M, Parés-Avila JA, Lizcano JA, et al. Linguistic and cultural adaptation of a computer-based counseling program (CARE+ Spanish) to support HIV treatment adherence and risk reduction for people living with HIV/AIDS: a randomized controlled trial . J Med Internet Res 2016; 18:e195.
Lelutiu-Weinberger C, Pachankis JE, Gamarel KE, Surace A, Golub SA, Parsons JT. Feasibility, acceptability, and preliminary efficacy of a live-chat social media intervention to reduce HIV risk among young men who have sex with men . AIDS Behav 2015; 19:1214–1227.
Lippman SA, Moran L, Sevelius J, Castillo LS, Ventura A, Treves-Kagan S, Buchbinder S. Acceptability and feasibility of HIV self-testing among transgender women in San Francisco: a mixed methods pilot study . AIDS Behav 2016; 20:928–938.
Marlin RW, Young SD, Bristow CC, Wilson G, Rodriguez J, Ortiz J, et al. Piloting an HIV self-test kit voucher program to raise serostatus awareness of high-risk African Americans, Los Angeles . BMC Public Health 2014; 14:1226.
Maulsby C, Jain KM, Weir BW, Enobun B, Werner M, Riordan M, et al. Cost-utility of access to care, a National HIV linkage, re-engagement and retention in care program . AIDS Behav 2018; 22:3734–3741.
Marhefka SL, Buhi ER, Baldwin J, Chen H, Johnson A, Lynn V, Glueckauf R. Effectiveness of healthy relationships video-group-A videoconferencing group intervention for women living with HIV: preliminary findings from a randomized controlled trial . Telemed J E Health 2014; 20:128–134.
Moitra E, Chan PA, Stein MD. Open trial of an acceptance-based behavior therapy intervention to engage newly diagnosed HIV patients in care: rationale and evidence of feasibility and acceptability . Behav Modif 2015; 39:670–690.
Nunn A, Towey C, Chan PA, Parker S, Nichols E, Oleskey P, et al. Routine HIV screening in an urban community health center: results from a geographically focused implementation science program . Public Health Rep 2016; 131: (Suppl 1): 30–40.
Raj A, Dasgupta A, Goldson I, Lafontant D, Freeman E, Silverman JG. Pilot evaluation of the Making Employment Needs [MEN] count intervention: addressing behavioral and structural HIV risks in heterosexual black men . AIDS Care 2014; 26:152–159.
Rana AI, van den Berg JJ, Lamy E, Beckwith CG. Using a mobile health intervention to support HIV treatment adherence and retention among patients at risk for disengaging with care . AIDS Patient Care STDS 2016; 30:178–184.
Reisner SL, White Hughto JM, Pardee DJ, Kuhns L, Garofalo R, Mimiaga MJ. LifeSkills for men (LS4M): pilot evaluation of a gender-affirmative HIV and STI prevention intervention for young adult transgender men who have sex with men . J Urban Health 2016; 93:189–205.
Smith LR, Amico KR, Fisher JD, Cunningham CO. 60 Minutes for health: examining the feasibility and acceptability of a low-resource behavioral intervention designed to promote retention in HIV care . AIDS Care 2018; 30:255–265.
Sullivan PS, White D, Rosenberg ES, Barnes J, Jones J, Dasgupta S, et al. Safety and acceptability of couples HIV testing and counseling for US men who have sex with men: a randomized prevention study . J Int Assoc Provid AIDS Care 2014; 13:135–144.
Sun CJ, García M, Mann L, Alonzo J, Eng E, Rhodes SD. Latino sexual and gender identity minorities promoting sexual health within their social networks: process evaluation findings from a lay health advisor intervention . Health Promot Pract 2015; 16:329–337.
Underhill K, Morrow KM, Colleran C, Calabrese SK, Operario D, Salovey P, Mayer KH. Explaining the efficacy of preexposure prophylaxis (PrEP) for HIV prevention: a qualitative study of message framing and messaging preferences among US men who have sex with men . AIDS Behav 2016; 20:1514–1526.
van der Straten A, Panther L, Laborde N, Hoesley CJ, Cheng H, Husnik MJ, et al. Adherence and acceptability of a multidrug vaginal ring for HIV prevention in a phase I study in the United States . AIDS Behav 2016; 20:2644–2653.
Witte SS, Wu E, El-Bassel N, Hunt T, Gilbert L, Medina KP, et al. Implementation of a couple-based HIV prevention program: a cluster randomized trial comparing manual versus web-based approaches . Implement Sci 2014; 9:116.
Wray T, Chan PA, Simpanen E, Operario D. eTEST: developing a smart home HIV testing kit that enables active, real-time follow-up and referral after testing . JMIR Mhealth Uhealth 2017; 5:e62.
Nilsen P. Making sense of implementation theories, models and frameworks . Implement Sci 2015; 10:53.
Green BB, Coronado GD, Schwartz M, Coury J, Baldwin LM. Using a continuum of hybrid effectiveness-implementation studies to put research-tested colorectal screening interventions into practice . Implement Sci 2019; 14:53.
Bernet AC, Willens DE, Bauer MS. Effectiveness-implementation hybrid designs: implications for quality improvement science . Implement Sci 2013; 8:S2.
Carroll C, Patterson M, Wood S, Booth A, Rick J, Balain S. A conceptual framework for implementation fidelity . Implement Sci 2007; 2:40.
Glasziou P, Meats E, Heneghan C, Shepperd S. What is missing from descriptions of treatment in trials and reviews? . BMJ 2008; 336:1472–1474.
Hoffmann TC, Erueti C, Glasziou PP. Poor description of nonpharmacological interventions: analysis of consecutive sample of randomised trials . BMJ 2013; 347:f3755.
NIH. NIH bolsters funding for HIV implementation research in high-burden U.S areas . Bethesda, MD: NIH; 2019.
Grant Information:: P30 AI042853 United States AI NIAID NIH HHS
Entry Date(s):: Date Created: 20201013 Date Completed: 20210406 Latest Revision: 20230921
Update Code:: 20240105
DOI:: 10.1097/QAD.0000000000002713
PMID:: 33048881
: Czasopismo naukowe

Objective: To provide the first systematic review of the early adoption of implementation science for HIV prevention or treatment in the United States. We identified primary research studies that addressed implementation of HIV prevention or treatment in the United States and qualitatively assessed the reporting of implementation outcomes and intervention descriptions.
Methods: We searched PubMed, PsycInfo, and CINAHL databases for evaluations of HIV prevention or treatment interventions that at least reported one implementation outcome and were published between 2014 and 2018. We used the 12-item Template for Intervention Description and Replication to assess study interventions.
Results: A total of 2275 articles were identified. Thirty-nine studies met inclusion criteria. Of these, 84.6% used quantitative methods with 5% being hybrid effectiveness-implementation studies and 15% used qualitative methods. No studies cited a formal theoretical framework for implementation science. Acceptability and feasibility were the most frequently reported implementation outcomes. Eligible studies were diverse with regard to demographic categories. Most interventions focused on HIV prevention, particularly risk-reduction strategies. HIV treatment interventions targeted linkage to care and adherence to medications. Key implementation outcome findings indicated that these interventions are feasible and acceptable in the real world.
Conclusion: HIV implementation science could support dissemination of HIV prevention or treatment in the United States, although HIV treatment interventions are limited. Theoretical frameworks and key implementation outcomes like fidelity, penetration, and appropriateness could promote the rigor of future HIV treatment implementation research, helping the field deliver the promise of HIV prevention or treatment efforts in the United States.
(Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.)

Comment in: AIDS. 2021 Feb 2;35(2):335-336. (PMID: 33394674)

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