Concurrent acute myositis and Guillain-Barre syndrome in Cytomegalovirus infection - a rare case report. - OpacWWW

Tytuł:: Concurrent acute myositis and Guillain-Barre syndrome in Cytomegalovirus infection - a rare case report.
Autorzy:: Sakthivadivel V; Department of Medicine, All India Institute of Medical Sciences Jodhpur, Jodhpur, Rajasthan, 342005, India.
Naveenraj P; Department of Medicine, All India Institute of Medical Sciences Jodhpur, Jodhpur, Rajasthan, 342005, India.
Kachhwaha A; Department of Medicine, All India Institute of Medical Sciences Jodhpur, Jodhpur, Rajasthan, 342005, India.
Kumar D; Department of Medicine, All India Institute of Medical Sciences Jodhpur, Jodhpur, Rajasthan, 342005, India. .
Anne PB; Department of Transfusion Medicine, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.
Elhence P; Department of Pathology, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.
Meena M; Department of Medicine, All India Institute of Medical Sciences Jodhpur, Jodhpur, Rajasthan, 342005, India.
Źródło:: BMC infectious diseases [BMC Infect Dis] 2020 Oct 17; Vol. 20 (1), pp. 768. Date of Electronic Publication: 2020 Oct 17.
Typ publikacji:: Case Reports; Journal Article
Język:: English
Imprint Name(s):: Original Publication: London : BioMed Central, [2001-
MeSH Terms:: Cytomegalovirus/*immunology
Cytomegalovirus Infections/*complications
Cytomegalovirus Infections/*diagnosis
Guillain-Barre Syndrome/*complications
Guillain-Barre Syndrome/*diagnosis
Myositis/*complications
Myositis/*diagnosis
Acute Disease ; Adult ; Antibodies, Viral/blood ; Cytomegalovirus Infections/therapy ; Diagnostic Errors ; Guillain-Barre Syndrome/therapy ; Humans ; Immunoglobulin M/blood ; Male ; Myositis/therapy ; Myositis/virology ; Pain ; Plasmapheresis ; Treatment Outcome
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Contributed Indexing:: Keywords: Acute myositis; Cytomegalovirus; Guillain-Barre syndrome; Molecular mimicry
Substance Nomenclature:: 0 (Antibodies, Viral)
0 (Immunoglobulin M)
Entry Date(s):: Date Created: 20201018 Date Completed: 20201027 Latest Revision: 20201027
Update Code:: 20240105
PubMed Central ID:: PMC7568349
DOI:: 10.1186/s12879-020-05506-5
PMID:: 33069216
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Pełny tekst

Background: Cytomegalovirus (CMV) is a double stranded DNA virus and ubiquitous in nature. Association of Guillain-Barre syndrome (GBS) and CMV is well known but CMV acute myositis is a rare condition. Restriction of movements of limbs due to severe pain in myositis may obscure the diagnosis of GBS and this may easily miss.
Case Presentation: Here we describe a 29-year-old male presenting with pain and swelling of bilateral lower limbs which progressed rapidly with increasing serum creatine kinase levels with positive IgM CMV antibodies. In view of no improvement in clinical condition, patient was further evaluated and found to have concurrent GBS. He was treated with plasmapheresis and improved.
Conclusion: Cytomegalovirus infection presenting as acute myositis is a uncommon and further association with GBS is a rare occurrence.

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Concurrent acute myositis and Guillain-Barre syndrome in Cytomegalovirus infection - a rare case report.