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Tytuł pozycji:

[Advances in oral bacteria influencing host epigenetic regulation].

Tytuł:
[Advances in oral bacteria influencing host epigenetic regulation].
Autorzy:
Mei HX; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Chen YL; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Shi PL; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Yang SR; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Xu X; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
He JZ; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Źródło:
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology [Hua Xi Kou Qiang Yi Xue Za Zhi] 2020 Oct 01; Vol. 38 (5), pp. 583-588.
Typ publikacji:
Journal Article; Review
Język:
Chinese
Imprint Name(s):
Publication: Chengdu : Sichuan yi xue yuan
Original Publication: Chengdu : Sichuan yi xue yuan, 1983-
MeSH Terms:
Epigenesis, Genetic*
Mouth Diseases*
Bacteria ; Gene Expression ; Humans ; Inflammation/genetics
References:
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Contributed Indexing:
Keywords: DNA methylation; epigenetics; histones modification; non-coding RNA; oral bacteria
Local Abstract: [Publisher, Chinese] 表观遗传是指非基因序列改变所导致的基因表达水平的稳定改变,微生物能通过表观遗传途径调节宿主炎症,从而逃避或者扩大免疫反应。口腔细菌作为人体微生物的重要组成部分,目前已发现多种表观遗传调控机制可影响宿主对口腔细菌的反应。本文就细菌调控表观遗传的常见途径以及不同疾病中口腔细菌对宿主表观遗传的调控进行综述,以期为口腔疾病中表观遗传相关机制研究提供参考。.
Entry Date(s):
Date Created: 20201021 Date Completed: 20201023 Latest Revision: 20201023
Update Code:
20240105
PubMed Central ID:
PMC7573781
DOI:
10.7518/hxkq.2020.05.019
PMID:
33085246
Czasopismo naukowe
Epigenetics refers to a steady change in the level of gene expression caused by non-DNA sequence changes. Microbes can modulate host inflammation through epigenetic pathways to evade or expend immune responses. As an important part of human microbes, oral bacteria also have various epigenetic regulation mechanisms to affect host inflammatory responses. This article reviews the common pathways of epigenetic regulation in microbe infection and the regulation of host epigenetics by using oral microbes to provide a reference for the study of epigenetic-related mechanisms in oral diseases.

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