Computational Assessment of Transport Distances in Living Skeletal Muscle Fibers Studied In Situ.

Szczegóły
Abstrakt

Tytuł:: Computational Assessment of Transport Distances in Living Skeletal Muscle Fibers Studied In Situ.
Autorzy:: Hansson KA; Department of Biosciences, Department of Biosciences, University of Oslo, Oslo, Norway; Center for Integrative Neuroplasticity, Department of Biosciences, University of Oslo, Oslo, Norway.
Solbrå AV; Department of Biosciences, Department of Biosciences, University of Oslo, Oslo, Norway; Center for Integrative Neuroplasticity, Department of Biosciences, University of Oslo, Oslo, Norway; Department of Physics, University of Oslo, Oslo, Norway.
Gundersen K; Department of Biosciences, Department of Biosciences, University of Oslo, Oslo, Norway; Center for Integrative Neuroplasticity, Department of Biosciences, University of Oslo, Oslo, Norway.
Bruusgaard JC; Department of Biosciences, Department of Biosciences, University of Oslo, Oslo, Norway; Center for Integrative Neuroplasticity, Department of Biosciences, University of Oslo, Oslo, Norway; Department of Health Sciences, Kristiania University College, Oslo, Norway. Electronic address: .
Źródło:: Biophysical journal [Biophys J] 2020 Dec 01; Vol. 119 (11), pp. 2166-2178. Date of Electronic Publication: 2020 Oct 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
Język:: English
Imprint Name(s):: Publication: Cambridge, MA : Cell Press
Original Publication: New York, Published by Rockefeller University Press [etc.] for the Biophysical Society.
MeSH Terms:: Muscle Fibers, Skeletal*
Muscle, Skeletal*
Animals ; Cell Nucleus ; Mice ; Muscle Fibers, Fast-Twitch
References:: Aging Cell. 2010 Oct;9(5):685-97. (PMID: 20633000)
Dev Cell. 2019 Apr 8;49(1):48-62.e3. (PMID: 30905770)
Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):2978-2986. (PMID: 31988126)
J Exp Biol. 2016 Jan;219(Pt 2):235-42. (PMID: 26792335)
J Phys Chem Lett. 2013 Mar 21;4(6):861-5. (PMID: 26291347)
Nature. 1985 Sep 5-11;317(6032):66-8. (PMID: 3839905)
Cell Tissue Res. 2013 Sep;353(3):539-48. (PMID: 23736382)
Acta Anat (Basel). 1957;30(1-4):351-7. (PMID: 13478336)
Biol Cell. 1998 Sep;90(5):407-26. (PMID: 9835015)
J Cell Biol. 1989 Mar;108(3):1025-37. (PMID: 2921278)
J Biol Chem. 2004 Sep 24;279(39):40699-706. (PMID: 15247264)
Development. 2013 Feb 1;140(3):617-26. (PMID: 23293293)
J Cell Biol. 1984 Jul;99(1 Pt 1):332-5. (PMID: 6547444)
Proc Natl Acad Sci U S A. 1967 Aug;58(2):592-8. (PMID: 5233460)
BMC Genomics. 2011 Jul 07;12:353. (PMID: 21736759)
Genes Dev. 1998 Sep 1;12(17):2748-58. (PMID: 9732272)
Int J Exp Pathol. 1992 Feb;73(1):51-60. (PMID: 1576078)
J Cell Biol. 1992 Dec;119(5):1063-8. (PMID: 1447288)
Development. 1991 Dec;113(4):1181-91. (PMID: 1811935)
Front Physiol. 2013 Dec 12;4:363. (PMID: 24376424)
Biophys J. 2000 Oct;79(4):2084-94. (PMID: 11023912)
EMBO J. 2005 Nov 2;24(21):3781-92. (PMID: 16237460)
J R Soc Interface. 2017 Jun;14(131):. (PMID: 28615492)
Am J Physiol. 1976 Aug;231(2):441-8. (PMID: 961895)
Neuromuscul Disord. 2010 Apr;20(4):223-8. (PMID: 20181480)
PLoS Comput Biol. 2018 Jun 11;14(6):e1006208. (PMID: 29889846)
Hum Gene Ther. 1999 Jan 20;10(2):291-300. (PMID: 10022553)
Early Hum Dev. 1985 Dec;12(3):211-39. (PMID: 3912156)
J Cell Biol. 2002 Jan 7;156(1):35-9. (PMID: 11781333)
Cell Metab. 2015 Dec 1;22(6):1033-44. (PMID: 26603188)
Anat Rec. 1997 Jul;248(3):346-54. (PMID: 9214552)
Cell. 2019 Feb 21;176(5):1083-1097.e18. (PMID: 30739799)
J Neurosci. 1999 Dec 15;19(24):10694-705. (PMID: 10594053)
Mol Biol Cell. 2006 Apr;17(4):2057-68. (PMID: 16467387)
Am J Physiol Cell Physiol. 2015 Nov 15;309(10):C669-79. (PMID: 26377314)
J Physiol. 2003 Sep 1;551(Pt 2):467-78. (PMID: 12813146)
Histochem Cell Biol. 2013 Jun;139(6):873-85. (PMID: 23275125)
J Cell Physiol. 2006 Dec;209(3):874-82. (PMID: 16972267)
Nature. 1989 Feb 9;337(6207):570-3. (PMID: 2915707)
Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):17876-82. (PMID: 22006304)
Dev Cell. 2016 Nov 7;39(3):370-382. (PMID: 27720611)
Cell. 1989 Dec 1;59(5):771-2. (PMID: 2686838)
J Appl Physiol (1985). 2006 Jun;100(6):2024-30. (PMID: 16497845)
Nature. 2012 Mar 18;484(7392):120-4. (PMID: 22425998)
Annu Rev Biophys. 2008;37:375-97. (PMID: 18573087)
Exp Cell Res. 1983 Apr 15;145(1):167-78. (PMID: 6852125)
Entry Date(s):: Date Created: 20201030 Date Completed: 20210514 Latest Revision: 20211203
Update Code:: 20240105
PubMed Central ID:: PMC7732813
DOI:: 10.1016/j.bpj.2020.10.016
PMID:: 33121941
: Czasopismo naukowe

Full Text Finder

Transport distances in skeletal muscle fibers are mitigated by these cells having multiple nuclei. We have studied mouse living slow (soleus) and fast (extensor digitorum longus) muscle fibers in situ and determined cellular dimensions and the positions of all the nuclei within fiber segments. We modeled the effect of placing nuclei optimally and randomly using the nuclei as the origin of a transportation network. It appeared that an equidistant positioning of nuclei minimizes transport distances along the surface for both muscles. In the soleus muscle, however, which were richer in nuclei, positioning of nuclei to reduce transport distances to the cytoplasm were of less importance, and these fibers exhibit a pattern not statistically different from a random positioning of nuclei. We also simulated transport times for myoglobin and found that they were remarkably similar between the two muscles despite differences in nuclear patterning and distances. Together, these results highlight the importance of spatially distributed nuclei to minimize transport distances to the surface when nuclear density is low, whereas it appears that the distribution are of less importance at higher nuclear densities.
(Copyright © 2020. Published by Elsevier Inc.)

Informacja