Late Effects in Childhood Cancer Survivors: Early Studies, Survivor Cohorts, and Significant Contributions to the Field of Late Effects.

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Tytuł:: Late Effects in Childhood Cancer Survivors: Early Studies, Survivor Cohorts, and Significant Contributions to the Field of Late Effects.
Autorzy:: Norsker FN; Childhood Cancer Research Group, Danish Cancer Society Research Center, Strandboulevarden 49, 2100 Copenhagen, Denmark.
Pedersen C; Childhood Cancer Research Group, Danish Cancer Society Research Center, Strandboulevarden 49, 2100 Copenhagen, Denmark.
Armstrong GT; Department of Epidemiology & Cancer Control, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Mail Stop 735, Memphis, TN 38105, USA.
Robison LL; Department of Epidemiology & Cancer Control, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Mail Stop 735, Memphis, TN 38105, USA.
McBride ML; Cancer Control Research, BC Cancer, 675 West 10th Avenue, Room 2.107, Vancouver, BC, V5Z 1L3, Canada.
Hawkins M; Centre for Childhood Cancer Survivor Studies, Institute of Applied Health Research, Robert Aitken Building, University of Birmingham, Birmingham B15 2TT, UK.
Kuehni CE; Swiss Childhood Cancer Registry, Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, CH-3012 Bern, Switzerland; Paediatric Oncology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 18, CH-3010 Bern, Switzerland.
de Vathaire F; Centre for Research in Epidemiology and Population Health, INSERM Unit 1018, Institut Gustave Roussy, University of Paris-Saclay, 114 Rue Edouard Vaillant, 94800 Villejuif, France.
Berbis J; Assistance Publique Hopitaux de Marseille, Aix-Marseille University, EA 3279 CEReSS, Health Service Research and Quality of Life Center, Faculté de Médecine 27, Bd Jean Moulin 13005 Marseille, France.
Kremer LC; Princess Maxima Center for Pediatric Oncology, University Medical Center Utrecht, Utrecht University, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.
Haupt R; IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini, 5, 16147 Genova, Italy.
Kenborg L; Childhood Cancer Research Group, Danish Cancer Society Research Center, Strandboulevarden 49, 2100 Copenhagen, Denmark. Electronic address: .
Winther JF; Childhood Cancer Research Group, Danish Cancer Society Research Center, Strandboulevarden 49, 2100 Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health, Incuba Skejby, building 2, Palle Juul-Jensens Boulevard 82, 8200 Aarhus N, Denmark.
Źródło:: Pediatric clinics of North America [Pediatr Clin North Am] 2020 Dec; Vol. 67 (6), pp. 1033-1049.
Typ publikacji:: Journal Article; Review
Język:: English
Imprint Name(s):: Publication: Philadelphia, PA : W.B. Saunders
Original Publication: Philadelphia.
MeSH Terms:: Biomedical Research*
Cancer Survivors*
Humans ; Publishing
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Grant Information:: U24 CA055727 United States CA NCI NIH HHS
Contributed Indexing:: Keywords: Cancer research; Childhood cancer survivors; Late effects; Long-term complications; Survivor cohorts
Entry Date(s):: Date Created: 20201102 Date Completed: 20210111 Latest Revision: 20211203
Update Code:: 20240105
PubMed Central ID:: PMC8393933
DOI:: 10.1016/j.pcl.2020.07.002
PMID:: 33131533
: Czasopismo naukowe

With improvement in cure of childhood cancer came the responsibility to investigate the long-term morbidity and mortality associated with the treatments accountable for this increase in survival. Several large cohorts of childhood cancer survivors have been established throughout Europe and North America to facilitate research on long-term complications of cancer treatment. The cohorts have made significant contributions to the understanding of early mortality, somatic late complications, and psychosocial outcomes among childhood cancer survivors, which has been translated into the design of new treatment protocols for pediatric cancers, with the goal to reduce the potential risk and severity of late effects.
Competing Interests: Disclosure The authors have nothing to disclose.
(Copyright © 2020 Elsevier Inc. All rights reserved.)

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