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Tytuł:
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Dispatching Sonic: A Eukaryotic RND Family Protein in the Hedgehog Signaling Cascade.
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Autorzy:
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Newstead S; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK. Electronic address: .
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Źródło:
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Developmental cell [Dev Cell] 2020 Nov 09; Vol. 55 (3), pp. 255-256.
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Typ publikacji:
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Journal Article; Comment
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Język:
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English
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Imprint Name(s):
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Original Publication: Cambridge, Mass. : Cell Press, c2001-
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MeSH Terms:
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Eukaryota*
Hedgehog Proteins*/genetics
Cations ; Cholesterol ; Signal Transduction
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Substance Nomenclature:
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0 (Cations)
0 (Hedgehog Proteins)
97C5T2UQ7J (Cholesterol)
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Entry Date(s):
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Date Created: 20201110 Date Completed: 20210304 Latest Revision: 20210304
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Update Code:
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20240105
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DOI:
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10.1016/j.devcel.2020.10.003
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PMID:
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33171107
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A study in this issue of Developmental Cell (Petrov et al., 2020) provides evidence that eukaryotic RND proteins function as cholesterol transport systems in the Hedgehog signaling pathway, driven by either sodium or potassium gradients.
(Copyright © 2020 Elsevier Inc. All rights reserved.)
Comment on: Dev Cell. 2020 Nov 9;55(3):314-327.e7. (PMID: 32860743)