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Tytuł:
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Eight weeks of resistance training with blood flow restriction improve cardiac function and vascular endothelial function in healthy young Asian males.
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Autorzy:
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Zhao Y; School of Sports and Health, Nanjing Sport Institute, 8 Linggusi Road, Nanjing, PA 210014, China.
Lin A; Department of Science and Technology, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, PA 210006, China.
Jiao L; Department of Rehabilitation, Kunshan Rehabilitation Hospital, 888 Yingbin Road, Kunshan, PA 215300, China.
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Źródło:
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International health [Int Health] 2021 Sep 03; Vol. 13 (5), pp. 471-479.
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Typ publikacji:
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Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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Język:
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English
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Imprint Name(s):
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Publication: 2013- : Oxford : Oxford University Press
Original Publication: -2012: Kidlington, Oxford : Elsevier
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MeSH Terms:
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Resistance Training*
Adult ; Hemodynamics ; Humans ; Male ; Regional Blood Flow ; Vascular Endothelial Growth Factor A
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References:
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Contributed Indexing:
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Keywords: blood flow restriction; cardiac function; haemodynamics; low-intensity resistance training; vascular endothelial function; vascular endothelial growth factor
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Substance Nomenclature:
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0 (Vascular Endothelial Growth Factor A)
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Entry Date(s):
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Date Created: 20201111 Date Completed: 20211004 Latest Revision: 20211004
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Update Code:
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20240105
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PubMed Central ID:
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PMC8417084
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DOI:
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10.1093/inthealth/ihaa089
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PMID:
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33175117
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Background: Resistance training with blood flow restriction (BFR) is a physiological ischaemic training method. Before it is applied to patients with coronary artery disease, it must be proven safe and effective.
Methods: Twenty-four healthy adult males were randomly assigned to three groups: the resistance training (RT) group, low-pressure BFR and resistance training (LP-RT) group and high-pressure BFR and resistance training (HP-RT) group. The training protocol was 20 times/min/set, with a 2-min break, five sets/day and 5 d/week for 8 weeks. Cardiac function, haemodynamics and vascular endothelial function were evaluated before and after the first training and the last training.
Results: There were no significant differences among groups before and after training. After 8 weeks of training, the resting heart rate (p<0.05) of the three groups significantly decreased (p<0.05). The rate-pressure product in the LP-RT group significantly decreased (p<0.05) compared with before training. Just after the last training, heart rate (p<0.05) and cardiac output (p<0.05) in the LP-RT and HP-RT groups significantly decreased compared with those just after the first training. At the end of the experiment, vascular endothelial growth factor (VEGF; p<0.01), soluble VEGF receptor (VEGFR) (p<0.05) and interleukin-6 (p<0.01) significantly increased, except for soluble VEGFR in the RT group.
Conclusions: Low-intensity resistance training with BFR moderately alters cardiac function. The expression levels of proteins related to vascular endothelial function have significantly changed. Both findings suggest that low-intensity resistance training with BFR may be safely and effectively applied to patients with coronary artery disease.
(© The Author(s) 2020. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.)
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