- Tytuł:
- Idiopathic pulmonary hemosiderosis: a review of the treatments used during the past 30 years and future directions.
- Autorzy:
- Źródło:
- Clinical rheumatology [Clin Rheumatol] 2021 Jul; Vol. 40 (7), pp. 2547-2557. Date of Electronic Publication: 2020 Nov 12.
- Typ publikacji:
- Journal Article; Review
- Język:
- English
- Imprint Name(s):
-
Publication: <2008->: Heidelberg : Springer
Original Publication: Brussels : Acta Medica Belgica, [1982- - MeSH Terms:
-
Hemosiderosis*/drug therapy
Lung Diseases*/drug therapy
Adult ; Azathioprine/therapeutic use ; Hemoptysis ; Humans ; Hemosiderosis, Pulmonary - References:
-
Milman N, Pedersen FM (1998) Idiopathic pulmonary haemosiderosis. Epidemiology, pathogenic aspects and diagnosis. Respiratory Medicine 92(7):902–907. (PMID: 10070562)
Chen X-Y, Sun J-M, Huang X-J (2017) Idiopathic pulmonary hemosiderosis in adults: review of cases reported in the latest 15 years. The Clinical Respiratory Journal 11(6):677–681. (PMID: 26692115)
Miwa S, Imokawa S, Kato M, Ide K, Uchiyama H, Yokomura K, Suda T, Shirai M, Hayakawa H, Chida K (2011) Prognosis in adult patients with idiopathic pulmonary hemosiderosis. Internal Medicine 50(17):1803–1808. (PMID: 21881278)
Ali AM, Milman N, Clausen PP, Reinert P, Pedersen FM, Jacobsen GK (1999) Idiopathic pulmonary haemosiderosis. Favourable effect of oral corticosteroids in two females aged 16 and 55 yrs. European Respiratory Topic 4:53–57.
Milman, N. Idiopathic pulmonary hemosiderosis. Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com . Accessed Oct 21, 2020.).
Taytard J, Nathan N, de Blic J, Fayon M, Epaud R, Deschildre A, Troussier F, Lubrano M, Chiron R, Reix P, Cros P, Mahloul M, Michon D, Clement A, Corvol H, for the French RespiRare® group (2013) New insights into pediatric idiopathic pulmonary hemosiderosis: the French RespiRare® cohort. Orphanet Journal of Rare Diseases 8:161. (PMID: 241255703852822)
Le Clainche L, Le Bourgeois M, Fauroux B, Forenza N, Dommergues JP, Desbois JC et al (2000) Long-term outcome of idiopathic pulmonary hemosiderosis in children. Medicine (Baltimore) 79(5):318–326.
Freitas A, Senra V, Marinho A, Guedes M (2015) Chronic alveolar haemorrhage in a paediatric patient: a diagnostic and treatment challenge. BML Case Reports 21:2015.
Buckley M, Van Mater H (2020) Idiopathic pulmonary hemosiderosis as a mimic of pulmonary vasculitis: a case report and review of the literature. Current Allergy and Asthma Reports 20(5):13. (PMID: 32248398)
Yanagihara T, Yamamoto Y, Hamada N, Suzuki K, Ogata-Suetsugu S, Harada E, Tagawa T, Fujiwara M, Hashisako M, Fukuoka J, Nakanishi Y (2018) Recurrent idiopathic pulmonary hemosiderosis after long-term remission presented with Sjogren’s syndrome: idiopathic no more? Respiratory Medicine Case Reports 25:68–72. (PMID: 299841516031097)
Stainer A, Rice A, Devaraj A, Barnett JL, Donovan J, Kokosi M, Nicholson AG, Cairns T, Wells AU, Renzoni EA (2019) Diffuse alveolar haemorrhage associated with subsequent development of ANCA positivity and emphysema in three young adults. BMC Pulmonary Medicine 19(1):185. (PMID: 316512926813980)
Ross B, Halloran K, Adam B, Laing B, Hirji A (2020) Disease recurrence after lung transplantation for idiopathic pulmonary hemosiderosis. Respiratory Medicine Case Reports 30:101128. (PMID: 325773697305376)
Wroblewski BM, Stefanovic CR, McDonough VM, Kidik PJ (1997) The challenges of idiopathic pulmonary hemosiderosis and lung transplantation. Critical Care Nurse 17(3):39–44. (PMID: 9313410)
Calabrese F, Giacometti C, Rea F, Loy M, Sartori F, Di Vittorio G et al (2002) Recurrence of idiopathic pulmonary hemosiderosis in a young adult patient after bilateral single-lung transplantation. Transplantation. 74(11):1643–1645. (PMID: 12490803)
Bavry AA, Knoper S, Alpert JS (2000) Segmental wall motion abnormalities in an individual with idiopathic pulmonary hemosiderosis. CRD. 93(3):201–204.
Sethi GR, Singhal KK, Puri AS, Mantan M (2011) Benefit of gluten-free diet in idiopathic pulmonary hemosiderosis in association with celiac disease. Pediatric Pulmonology 46(3):302–305. (PMID: 20967850)
Khemiri M, Ouederni M, Khaldi F, Barsaoui S (2008) Screening for celiac disease in idiopathic pulmonary hemosiderosis. Gastroentérologie Clinique et Biologique 32(8–9):745–748. (PMID: 18603390)
Alimi A, Taytard J, Abou Taam R, Houdouin V, Forgeron A, Lubrano Lavadera M et al (2018) Pulmonary hemosiderosis in children with Down syndrome: a national experience. Orphanet Journal of Rare Diseases 13(1):60. (PMID: 296781395910623)
Watanabe H, Ayusawa M, Kato M, Chou A, Komori A, Abe Y, Matsumura M, Kamiyama H, Izumi H, Takahashi S (2015) Idiopathic pulmonary hemosiderosis complicated by Down syndrome. Pediatrics International 57(5):1009–1012. (PMID: 26508184)
Oviedo Ramírez MI, Hop K, Carrera E, Soriano Rosas J (2010) Idiopathic pulmonary haemosiderosis in a young adult. Autopsy findings. Archivos de Bronconeumología 46(10):565–567. (PMID: 20708835)
Moissidis I, Chaidaroon D, Vichyanond P, Bahna SL (2005) Milk-induced pulmonary disease in infants (Heiner syndrome). Pediatric Allergy and Immunology 16(6):545–552. (PMID: 16176405)
Torres MJ, Girón MD, Corzo JL, Rodriguez F, Moreno F, Perez E et al (1996) Release of inflammatory mediators after cow’s milk intake in a newborn with idiopathic pulmonary hemosiderosis. The Journal of Allergy and Clinical Immunology 98(6 Pt 1):1120–1123. (PMID: 8977515)
Dearborn DG, Smith PG, Dahms BB, Allan TM, Sorenson WG, Montana E, Etzel RA (2002) Clinical profile of 30 infants with acute pulmonary hemorrhage in Cleveland. Pediatrics. 110(3):627–637. (PMID: 12205270)
Dearborn DG, Yike I, Sorenson WG, Miller MJ, Etzel RA (1999) Overview of investigations into pulmonary hemorrhage among infants in Cleveland, Ohio. Environmetal Health Perspectives 107(Suppl 3):495–499.
Kania A, Misiaszek M, Vašáková M, Szlubowski A, Bugalho A, Pankowski J, Szołkowska M, Roden AC, Celejewska-Wójcik N, Nastałek P, Gnass M, Sładek K (2019) Cryobiopsy in the diagnosis of idiopathic pulmonary hemosiderosis: a case report. Journal of Thoracic Disease 11(7):3195–3201. (PMID: 314631516687971)
Kiper N, Göçmen A, Özçelik U, Dilber E, Anadol D (1999) Long-term clinical course of patients with idiopathic pulmonary hemosiderosis (1979–1994): prolonged survival with low-dose corticosteroid therapy. Pediatric Pulmonology 27(3):180–184. (PMID: 10213256)
Ohga S, Takahashi K, Miyazaki S, Kato H, Ueda K (1995) Idiopathic pulmonary haemosiderosis in Japan: 39 possible cases from a survey questionnaire. European Journal of Pediatrics 154(12):994–995. (PMID: 8801109)
Chin CIC, Kohn SL, Keens TG, Margetis MF, Kato RM (2015) A physician survey reveals differences in management of idiopathic pulmonary hemosiderosis. Orphanet Journal of Rare Diseases 10:98. (PMID: 262892514545926)
Tobler A, Meier R, Seitz M, Dewald B, Baggiolini M, Fey MF (1992) Glucocorticoids downregulate gene expression of GM-CSF, NAP-1/IL-8, and IL-6, but not of M-CSF in human fibroblasts. Blood. 79(1):45–51. (PMID: 1370208)
Newton R (2000) Molecular mechanisms of glucocorticoid action: what is important? Thorax. 55(7):603–613. (PMID: 108563221745805)
Li Y-T, Guo Y-X, Cai L-M, Pan L, Duan M-Q, Yang L-F et al (2017) Methylprednisolone pulse therapy rescued life-threatening pulmonary hemorrhage due to idiopathic pulmonary hemosiderosis. The American Journal of Emergency Medicine 35(11):1786.e3–1786.e7.
Zhang Y, Luo F, Wang N, Song Y, Tao Y (2019) Clinical characteristics and prognosis of idiopathic pulmonary hemosiderosis in pediatric patients. The Journal of International Medical Research 47(1):293–302. (PMID: 30278795)
Colombo JL, Stolz SM (1992) Treatment of life-threatening primary pulmonary hemosiderosis with cyclophosphamide. Chest.
Naithani R, Chandra J, Singh V, Kumar V, Dubey NK (2006) Life threatening exacerbation in idiopathic pulmonary hemosiderosis salvaged by cyclophosphamide infusion. The Indian Journal of Chest Diseases & Allied Sciences 48(4):287–289.
Helman DL, Sullivan A, Kariya ST, Deering SH, Hueppchen NA, Shorr AF (2003) Management of idiopathic pulmonary haemosiderosis in pregnancy: report of two cases. Respirology. 8(3):398–400. (PMID: 14528889)
Kabra SK, Bhargava S, Lodha R, Satyavani A, Walia M (2007) Idiopathic pulmonary hemosiderosis: clinical profile and follow up of 26 children. Indian Pediatrics 44(5):333–338. (PMID: 17536132)
Castellazzi, L., Patria, M. F., Frati, G., Esposito, A. A., Esposito, S. (2016). Idiopathic pulmonary haemosiderosis in paediatric patients: how to make an early diagnosis. Italian Journal of Pediatrics [Internet]. [cited 2020 Oct 5];42. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029079/.
Pal P, De H, Giri PP, Ganguly N, Mandal A (2019) Early initiation of steroid-sparing drugs in idiopathic pulmonary hemosiderosis. Indian Pediatrics 56(1):73–74. (PMID: 30806370)
Doi T, Ohga S, Ishimura M, Takada H, Ishii K, Ihara K, Nagai H, Hara T (2013) Long-term liposteroid therapy for idiopathic pulmonary hemosiderosis. European Journal of Pediatrics 172(11):1475–1481. (PMID: 23812505)
Sakamoto R, Matsumoto S, Mitsubuchi H, Nakamura K (2018) Liposteroid and methylprednisolone combination therapy for a case of idiopathic lung hemosiderosis. Respiratory Medicine Case Reports 24:22–24. (PMID: 299777506010611)
Mizushima Y, Hamano T, Yokoyama K (1982) Tissue distribution and anti-inflammatory activity of corticosteroids incorporated in lipid emulsion. Annals of the Rheumatic Diseases 41(3):263–267. (PMID: 68964291000924)
Wakiguchi H, Ohga S (2016) Clinical utility of the liposteroid therapy: potential effects on the macrophage activation. Nihon Rinshō Men'eki Gakkai Kaishi 39(3):190–196. (PMID: 27320934)
Hoshi K, Mizushima Y, Shiokawa Y, Kageyama T, Honma M, Kashiwazaki S, Shichikawa K, Tsunematsu T, Kaneko K (1985) Double-blind study with liposteroid in rheumatoid arthritis. Drugs under Experimental and Clinical Research 11(9):621–626. (PMID: 3916836)
Doi T, Ohga S, Ishimura M, Takada H, Ishii K, Ihara K, Nagai H, Hara T (2015) Erratum to: long-term liposteroid therapy for idiopathic pulmonary hemosiderosis. European Journal of Pediatrics 174(12):1701–1701. (PMID: 26424556)
Tobai, H., Yano, J., Sato, N., Amanuma, F., Takahashi, M., Endo, M., et al. (2020). Successful liposteroid therapy for a recurrent idiopathic pulmonary hemosiderosis with Down syndrome [Internet]. Vol. 2020, Case Reports in Pediatrics. Hindawi [cited 2020 Aug 15]. p. e5292947. Available from: https://www.hindawi.com/journals/cripe/2020/5292947/.
Mushtaq A, Khatoon S, Qureshi MA (2015) Use of corticosteroids in the management of idiopathic pulmonary haemosiderosis: do we have enough evidence. Pakistan Journal of Medical Sciences 31(2):487–489. (PMID: 261015184476369)
Hall AG, Tilby MJ (1992) Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies. Blood Reviews 6(3):163–173. (PMID: 1422285)
Yao T-C, Hung I-J, Wong K-S, Huang J-L, Niu C-K (2003) Idiopathic pulmonary haemosiderosis: an oriental experience. Journal of Paediatrics and Child Health 39(1):27–30. (PMID: 12542808)
Flanagan F, Glackin L, Slattery DM (2013) Successful treatment of idiopathic pulmonary capillaritis with intravenous cyclophosphamide. Pediatric Pulmonology 48(3):303–305. (PMID: 22573417)
de Groot K, Harper L, Jayne DRW, Flores Suarez LF, Gregorini G, Gross WL, Luqmani R, Pusey CD, Rasmussen N, Sinico RA, Tesar V, Vanhille P, Westman K, Savage CO, EUVAS (European Vasculitis Study Group) (2009) Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized trial. Annals of Internal Medicine 150(10):670–680. (PMID: 19451574)
Harper L, Morgan MD, Walsh M, Hoglund P, Westman K, Flossmann O, Tesar V, Vanhille P, de Groot K, Luqmani R, Flores-Suarez LF, Watts R, Pusey C, Bruchfeld A, Rasmussen N, Blockmans D, Savage CO, Jayne D, EUVAS investigators (2012) Pulse versus daily oral cyclophosphamide for induction of remission in ANCA-associated vasculitis: long-term follow-up. Annals of the Rheumatic Diseases 71(6):955–960. (PMID: 22128076)
Merkel, P. A., Kaplan, A. A., Falk, R. J. (2020) Granulomatosis with polyangiitis and microscopic polyangiitis: induction and maintenance therapy. In: Appel GB, Fervenza FC, editor. UpToDate. Waltham: UpToDate Inc.
Airaghi L, Ciceri L, Giannini S, Ferrero S, Meroni PL, Tedeschi A (2001) Idiopathic pulmonary hemosiderosis in an adult. Favourable response to azathioprine. Monaldi Archives for Chest Disease 56(3):211–213. (PMID: 11665500)
Kamienska E, Urasinski T, Gawlikowska-Sroka A, Glura B, Pogorzelski A (2009) Idiopathic pulmonary hemosiderosis in a 9-year-old girl. European Journal of Medical Research 14(Suppl 4):112–115. (PMID: 201567393521338)
Butt A, Ahmed R, Sheikh MDA, Khan O, Iqbal N, Rahman AJ et al (2020) Idiopathic pulmonary hemosiderosis - a rare cause of chronic anemia. Monaldi Archives for Chest Disease 90(2).
Saeed MM, Woo MS, MacLaughlin EF, Margetis MF, Keens TG (1999) Prognosis in pediatric idiopathic pulmonary hemosiderosis. Chest. 116(3):721–725. (PMID: 10492278)
Rossi GA, Balzano E, Battistini E, Oddera S, Marchese P, Acquila M, Fregonese B, Mori PG (1992) Long-term prednisone and azathioprine treatment of a patient with idiopathic pulmonary hemosiderosis. Pediatric Pulmonology 13(3):176–180. (PMID: 1437333)
Luo X-Q, Ke Z-Y, Huang L-B, Guan X-Q, Zhang X-L, Zhu J, Zhang YC (2008) Maintenance therapy with dose-adjusted 6-mercaptopurine in idiopathic pulmonary hemosiderosis. Pediatric Pulmonology 43(11):1067–1071. (PMID: 18972408)
Lennard L (2002) TPMT in the treatment of Crohn’s disease with azathioprine. Gut. 51(2):143–146. (PMID: 121178661773327)
Ben-Zvi I, Kivity S, Langevitz P, Shoenfeld Y (2012) Hydroxychloroquine: from malaria to autoimmunity. Clinical Reviews in Allergy and Immunology 42(2):145–153. (PMID: 21221847)
Schrezenmeier E, Dörner T (2020) Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology. Nature Reviews Rheumatology 16(3):155–166. (PMID: 32034323)
Mackenzie AH (1983) Dose refinements in long-term therapy of rheumatoid arthritis with antimalarials. The American Journal of Medicine 75(1):40–45. (PMID: 6869410)
Saha, B. K., Bonnier, A., Chong, W. (2020). Antimalarials as antivirals for COVID-19: believe it or not! The American Journal of the Medical Sciences [Internet]. [cited 2020 Oct 26]; Available from: http://www.sciencedirect.com/science/article/pii/S0002962920303712 .
Aceti A, Sciutti R, Bracci PR, Bertelli L, Melchionda F, Cazzato S (2012) Idiopathic pulmonary haemosiderosis in a child with Down’s syndrome: case report and review of the literature. Sarcoidosis, Vasculitis, and Diffuse Lung Diseases 29(1):58–61. (PMID: 23311126)
García-Luzardo M d R, Aguilar-Fernández AJ, Cabrera-Roca G (2010) Idiopathic pulmonary haemosiderosis in childhood: a good response to systemic steroids, inhaled hydroxychloroquine and budesonide. Archivos de Bronconeumología 46(11):612–613.
Stone JH, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Turkiewicz A, Tchao NK, Webber L, Ding L, Sejismundo LP, Mieras K, Weitzenkamp D, Ikle D, Seyfert-Margolis V, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh KA, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Specks U, RAVE-ITN Research Group (2010) Rituximab versus cyclophosphamide for ANCA-associated vasculitis. The New England Journal of Medicine 363(3):221–232. (PMID: 206471993137658)
Jones RB, Cohen Tervaert JW, Hauser T, Luqmani R, Morgan MD, Peh CA et al (2010) Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis. The New England Journal of Medicine 363(3):211–220. (PMID: 20647198)
van den Brand JAJG, Ruggenenti P, Chianca A, Hofstra JM, Perna A, Ruggiero B, Wetzels JFM, Remuzzi G (2017) Safety of rituximab compared with steroids and cyclophosphamide for idiopathic membranous nephropathy. JASN. 28(9):2729–2737. (PMID: 28487395)
Lopez-Olivo MA, Amezaga Urruela M, McGahan L, Pollono EN, Suarez-Almazor ME (2015) Rituximab for rheumatoid arthritis. Cochrane Database of Systematic Reviews 1:CD007356.
Ac A, Em E (1996) Purine metabolism and immunosuppressive effects of mycophenolate mofetil (MMF). Clinical Transplants 10(1 Pt 2):77–84.
van Gelder T, Hesselink DA (2015) Mycophenolate revisited. Transplant International 28(5):508–515. (PMID: 25758949)
Xu L-H, Ou R-Q, Wu B-J, Wang H-Y, Fang J-P, Tan W-P (2017) Corticosteroid in combination with leflunomide and mesenchymal stem cells for treatment of pediatric idiopathic pulmonary hemosiderosis. Journal of Tropical Pediatrics 63(5):389–394. (PMID: 28158572)
Wang L-T, Ting C-H, Yen M-L, Liu K-J, Sytwu H-K, Wu KK, Yen BL (2016) Human mesenchymal stem cells (MSCs) for treatment towards immune- and inflammation-mediated diseases: review of current clinical trials. Journal of Biomedical Science 23(1):76. (PMID: 278099105095977)
Engela AU, Baan CC, Litjens NHR, Franquesa M, Betjes MGH, Weimar W, Hoogduijn MJ (2013) Mesenchymal stem cells control alloreactive CD8(+) CD28(−) T cells. Clinical and Experimental Immunology 174(3):449–458. (PMID: 240286563826311)
Flowers MED, Martin PJ (2015) How we treat chronic graft-versus-host disease. Blood. 125(4):606–615. (PMID: 253989334304105)
Dulamea A (2015) Mesenchymal stem cells in multiple sclerosis - translation to clinical trials. Journal of Medicine and Life 8(1):24–27. (PMID: 259147334397514)
Dazzi F, Krampera M (2011) Mesenchymal stem cells and autoimmune diseases. Best Practice & Research. Clinical Haematology 24(1):49–57.
Dave M, Mehta K, Luther J, Baruah A, Dietz AB, Faubion WA Jr (2015) Mesenchymal stem cell therapy for inflammatory bowel disease: a systematic review and meta-analysis. Inflammatory Bowel Diseases 21(11):2696–2707. (PMID: 262308634615553)
Domínguez-Bendala J, Lanzoni G, Inverardi L, Ricordi C (2012) Concise review: mesenchymal stem cells for diabetes. Stem Cells Translational Medicine 1(1):59–63. (PMID: 23197641)
Matsumoto S, Nakagawa S (2019) Extracorporeal membrane oxygenation for diffuse alveolar hemorrhage caused by idiopathic pulmonary hemosiderosis: a case report and a review of the literature. J Pediatr Intensive Care 8(3):181–186. (PMID: 314044356687456)
Gutierrez S, Shaw S, Huseni S, Sachdeva S, Costello JP, Basu S, Nath DS, Klugman D (2014) Extracorporeal life support for a 5-week-old infant with idiopathic pulmonary hemosiderosis. European Journal of Pediatrics 173(12):1573–1576. (PMID: 23942745)
Sun L-C, Tseng Y-R, Huang S-C, Huang P-M, Ko W-J, Lu FL, Wu ET (2006) Extracorporeal membrane oxygenation to rescue profound pulmonary hemorrhage due to idiopathic pulmonary hemosiderosis in a child. Pediatric Pulmonology 41(9):900–903. (PMID: 16850442)
Thornton G, Alotaibi M (2016) 979: idiopathic pulmonary hemosiderosis in adult patients: an epidemiologic analysis. Critical Care Medicine 44(12):321. - Contributed Indexing:
- Keywords: Idiopathic pulmonary hemosiderosis; Mesenchymal cell transplant; Pulmonary hemorrhage; Rituximab; Treatment
- Substance Nomenclature:
- MRK240IY2L (Azathioprine)
- Entry Date(s):
- Date Created: 20201113 Date Completed: 20210611 Latest Revision: 20231213
- Update Code:
- 20240105
- DOI:
- 10.1007/s10067-020-05507-4
- PMID:
- 33184706
- Czasopismo naukowe
Menu główne
Wyszukiwarka
Treść główna
