Responses to Treatment According to the Cytokine Profiles of Pericardial Effusion in Two Children with Idiopathic Pericarditis.

Szczegóły
Abstrakt

Tytuł:: Responses to Treatment According to the Cytokine Profiles of Pericardial Effusion in Two Children with Idiopathic Pericarditis.
Autorzy:: Motonaga T; Department of Pediatrics, Yamaguchi University Graduate School of Medicine.
Furuta T; Department of Pediatrics, Yamaguchi University Graduate School of Medicine.
Okada S; Department of Pediatrics, Yamaguchi University Graduate School of Medicine.
Ohnishi Y; Department of Pediatrics, Yamaguchi University Graduate School of Medicine.
Suzuki Y; Department of Pediatrics, Yamaguchi University Graduate School of Medicine.
Yasudo H; Department of Pediatrics, Yamaguchi University Graduate School of Medicine.
Hasegawa S; Department of Pediatrics, Yamaguchi University Graduate School of Medicine.
Źródło:: International heart journal [Int Heart J] 2020 Nov 28; Vol. 61 (6), pp. 1307-1310. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji:: Case Reports; Journal Article
Język:: English
Imprint Name(s):: Original Publication: [Tokyo, Japan] : International Heart Journal Association, [2005]-
MeSH Terms:: Anti-Bacterial Agents/*therapeutic use
Anti-Inflammatory Agents/*therapeutic use
Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use
Interleukin-10/*immunology
Interleukin-6/*immunology
Pericardial Effusion/*drug therapy
Pericarditis/*drug therapy
Aspirin/therapeutic use ; Cardiotonic Agents/therapeutic use ; Cefotaxime/therapeutic use ; Child, Preschool ; Cytokines/immunology ; Dobutamine/therapeutic use ; Dopamine/therapeutic use ; Humans ; Infant ; Male ; Meropenem/therapeutic use ; Pericardial Effusion/diagnostic imaging ; Pericardial Effusion/immunology ; Pericardial Fluid/immunology ; Pericarditis/diagnostic imaging ; Pericarditis/immunology ; Prednisolone/therapeutic use ; Treatment Outcome
Contributed Indexing:: Keywords: Acute pericarditis; Non-steroidal anti-inflammatory drugs; Pediatric population; Proinflammatory cytokine; Steroid
Substance Nomenclature:: 0 (Anti-Bacterial Agents)
0 (Anti-Inflammatory Agents)
0 (Anti-Inflammatory Agents, Non-Steroidal)
0 (Cardiotonic Agents)
0 (Cytokines)
0 (IL10 protein, human)
0 (IL6 protein, human)
0 (Interleukin-6)
130068-27-8 (Interleukin-10)
3S12J47372 (Dobutamine)
9PHQ9Y1OLM (Prednisolone)
FV9J3JU8B1 (Meropenem)
N2GI8B1GK7 (Cefotaxime)
R16CO5Y76E (Aspirin)
VTD58H1Z2X (Dopamine)
Entry Date(s):: Date Created: 20201116 Date Completed: 20201221 Latest Revision: 20201221
Update Code:: 20240105
DOI:: 10.1536/ihj.20-282
PMID:: 33191347
: Czasopismo naukowe

Acute pericarditis is inflammation of the pericardium with or without pericardial effusion. In the pediatric population, most patients with acute pericarditis are diagnosed with idiopathic pericarditis. Herein, we present two children with idiopathic pericarditis who underwent immunological assessment of pericardial effusion for the first time. Both patients showed equally high levels of interleukin-6 in the pericardial effusion. However, they had different treatment responses, in accordance with the pericardial effusion and serum interleukin-10 concentrations. Our present cases suggest that interleukin-10 may be associated with the response to anti-inflammatory therapy in idiopathic acute pericarditis.

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