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Tytuł:
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Quantification of calcium burden by coronary CT angiography compared to optical coherence tomography.
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Autorzy:
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Monizzi G; Cardiovascular Center Aalst, Onze-Lieve-Vrouw Hospital, Moorselbaan 164, 9300, Aalst, Belgium.; Centro Cardiologico Monzino, IRCCS, Milan, Italy.; Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, Milan, Italy.
Sonck J; Cardiovascular Center Aalst, Onze-Lieve-Vrouw Hospital, Moorselbaan 164, 9300, Aalst, Belgium.; Department of Advanced Biomedical Sciences, University of Napels, Federico II, Napels, Italy.
Nagumo S; Cardiovascular Center Aalst, Onze-Lieve-Vrouw Hospital, Moorselbaan 164, 9300, Aalst, Belgium.; Division of Cardiology, Department of Internal Medicine, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, 2278501, Japan.
Buytaert D; Cardiovascular Center Aalst, Onze-Lieve-Vrouw Hospital, Moorselbaan 164, 9300, Aalst, Belgium.
Van Hoe L; Radiology Department, OLV Ziekenhuis Aalst, Aalst, Oost-Vlaanderen, Belgium.
Grancini L; Centro Cardiologico Monzino, IRCCS, Milan, Italy.
Bartorelli AL; Centro Cardiologico Monzino, IRCCS, Milan, Italy.; Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, Milan, Italy.
Vanhoenacker P; Radiology Department, OLV Ziekenhuis Aalst, Aalst, Oost-Vlaanderen, Belgium.
Simons P; Radiology Department, OLV Ziekenhuis Aalst, Aalst, Oost-Vlaanderen, Belgium.
Bladt O; Radiology Department, OLV Ziekenhuis Aalst, Aalst, Oost-Vlaanderen, Belgium.
Wyffels E; Cardiovascular Center Aalst, Onze-Lieve-Vrouw Hospital, Moorselbaan 164, 9300, Aalst, Belgium.
De Bruyne B; Cardiovascular Center Aalst, Onze-Lieve-Vrouw Hospital, Moorselbaan 164, 9300, Aalst, Belgium.
Andreini D; Centro Cardiologico Monzino, IRCCS, Milan, Italy.; Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, Milan, Italy.
Collet C; Cardiovascular Center Aalst, Onze-Lieve-Vrouw Hospital, Moorselbaan 164, 9300, Aalst, Belgium. .
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Źródło:
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The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2020 Dec; Vol. 36 (12), pp. 2393-2402. Date of Electronic Publication: 2020 Nov 17.
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Typ publikacji:
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Comparative Study; Journal Article; Observational Study
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Język:
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English
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Imprint Name(s):
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Publication: [New York] : Springer
Original Publication: Boston : Kluwer Academic Publishers, c2001-
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MeSH Terms:
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Computed Tomography Angiography*
Coronary Angiography*
Tomography, Optical Coherence*
Coronary Artery Disease/*diagnostic imaging
Coronary Vessels/*diagnostic imaging
Vascular Calcification/*diagnostic imaging
Aged ; Coronary Artery Disease/therapy ; Female ; Humans ; Male ; Middle Aged ; Percutaneous Coronary Intervention ; Predictive Value of Tests ; Reproducibility of Results ; Severity of Illness Index ; Vascular Calcification/therapy
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Contributed Indexing:
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Keywords: Calcium; Coronary CT; OCT; PCI
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Entry Date(s):
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Date Created: 20201118 Date Completed: 20201209 Latest Revision: 20201214
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Update Code:
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20240105
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DOI:
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10.1007/s10554-020-01839-z
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PMID:
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33205340
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Coronary artery calcifications (CAC) are frequently observed in patients referred for coronary CT angiography (CTA). Calcification volume (in mm 3 ) can accurately be assessed during catheterization by optical coherence tomography (OCT). The aim of the present study was to investigate the accuracy of CTA-derived assessment of calcification volume as compared with OCT. 66 calcified plaques (32 vessels) from 31 patients undergoing OCT-guided PCI with coronary CT acquired as a standard of care were included. Coronary CT and OCT images were matched using fiduciary points. Calcified plaques were reconstructed in three dimensions to calculate calcium volume. A Passing-Bablok regression analysis and the Bland-Altman method were used to assess the agreement between imaging modalities. Twenty-seven left anterior descending arteries and 5 right coronary arteries were analyzed. Median calcium volume by CTA and OCT were 18.23 mm 3 [IQR 8.09, 36.48] and 10.03 mm 3 [IQR 3.6, 22.88] respectively; the Passing-Bablok analysis showed a proportional without a systematic difference (Coefficient A 0.08, 95% CI - 1.37 to 1.21, Coefficient B 1.61, 95% CI 1.45 to 1.84) and the mean difference was 9.69 mm3 (LOA - 10.2 to 29.6 mm 3 ). No differences were observed for minimal lumen area (Coefficient A 0.07, 95% CI - 0.46 to 0.15, Coefficient B 0.85, 95% CI 0.64 to 1.2). CTA volumetric calcium evaluation overestimates calcium volume by 60% compared to OCT. This may allow for an appropriate interpretation of calcific burden in the non-invasive setting. Even in presence of calcific plaques, a good agreement in the MLA assessment was found. Coronary CT may emerge as a tool to quantify calcium burden for invasive procedural planning.
