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Tytuł:
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Co-exposures to trace elements and polycyclic aromatic compounds (PACs) impacts North American river otter (Lontra canadensis) baculum.
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Autorzy:
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Thomas PJ; Science and Technology Branch, Environment and Climate Change Canada, National Wildlife Research Center, 1125 Colonel By Drive, Raven Road, Ottawa, ON, Canada, K1A 0H3. Electronic address: .
Newell EE; Department of Mechanical Engineering, McMaster University, 1280 Main Street W, Hamilton, ON, Canada, L8S 4L8.
Eccles K; Department of Geography, Geomatics and Environment, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, ON, Canada, L5L 1C6.
Holloway AC; Department of Obstetrics and Gynecology, McMaster University, 1280 Main Street W, Hamilton, ON, L8S 4L8, Canada.
Idowu I; Centre for Oil and Gas Research and Development, Department of Chemistry, University of Manitoba, 584 Parker Building, Winnipeg, MB, R3T 2N2, Canada.
Xia Z; Centre for Oil and Gas Research and Development, Department of Chemistry, University of Manitoba, 584 Parker Building, Winnipeg, MB, R3T 2N2, Canada.
Hassan E; Department of Mechanical Engineering, McMaster University, 1280 Main Street W, Hamilton, ON, Canada, L8S 4L8.
Tomy G; Centre for Oil and Gas Research and Development, Department of Chemistry, University of Manitoba, 584 Parker Building, Winnipeg, MB, R3T 2N2, Canada.
Quenneville C; Department of Mechanical Engineering, McMaster University, 1280 Main Street W, Hamilton, ON, Canada, L8S 4L8; School of Biomedical Engineering, McMaster University, 1280 Main Street W, Hamilton, ON, Canada, L8S 4L8.
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Źródło:
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Chemosphere [Chemosphere] 2021 Feb; Vol. 265, pp. 128920. Date of Electronic Publication: 2020 Nov 10.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: Oxford : Elsevier Science Ltd
Original Publication: Oxford, New York, : Pergamon Press.
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MeSH Terms:
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Otters*
Polycyclic Compounds*
Trace Elements*
Alberta ; Animals ; Ecosystem ; Environmental Monitoring ; Male ; Oil and Gas Fields
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Contributed Indexing:
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Keywords: Biological effect; Bone mineral density; Complex mixture; Endocrine disrupting compound (EDC); Liver; Reproductive toxicity
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Substance Nomenclature:
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0 (Polycyclic Compounds)
0 (Trace Elements)
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Entry Date(s):
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Date Created: 20201120 Date Completed: 20210101 Latest Revision: 20210101
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Update Code:
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20240105
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DOI:
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10.1016/j.chemosphere.2020.128920
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PMID:
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33213878
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Environmental loadings of polycyclic aromatic compounds (PACs) and trace elements are increasing in areas with marked oil and gas extraction, such as in the Athabasca oil sands region, Alberta, Canada. Some of these chemicals are recognized as potent endocrine disrupting compounds (EDCs). The impacts of co-exposure to PACs and metals on free-ranging wildlife is of considerable concern. River otters (Lontra canadensis) are sentinel species of aquatic ecosystem health. The baculum (penile bone) is an important part of the reproductive system in otters that ensures successful copulation. Although baculum health is critical to male reproductive success and is sensitive to exposure to EDCs, there is no information available regarding the impact of PAC and metal exposures on measures of baculum health. River otter baculum and livers were dissected from carcasses obtained from the fur trade. Trace element and PAC analyses were carried out in liver with matching baculums subjected to dimensional analysis, bone mineral density (BMD) and mechanical loading testing. Trace elements and select PACs exhibited both protective and deleterious effects on baculum bone health metrics. Alkylated four ring PACs were negatively associated with baculum bone material properties (ex: C4-Chrysene and C4-pyrene). The same compounds have been shown to exhibit strong anti-androgenic activities. Few comparable studies exist related to contamination and adverse effects of PACs in wild terrestrial mammals. Baculum health metrics may be an important tool to include in biomonitoring studies as to date, there are limited means to assess male reproductive performance in wildlife biomonitoring programs.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Crown Copyright © 2020. Published by Elsevier Ltd. All rights reserved.)
