Risk factors for recurrent pulmonary exacerbation in idiopathic pulmonary hemosiderosis.

Szczegóły
Abstrakt

Tytuł:: Risk factors for recurrent pulmonary exacerbation in idiopathic pulmonary hemosiderosis.
Autorzy:: Hizal M; Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Eryilmaz Polat S; Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Ramasli Gursoy T; Pediatric Pulmonology, Gazi University Faculty of Medicine, Ankara, Turkey.
Ozsezen B; Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Ademhan Tural D; Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Karakaya J; Department of Biostatistic, Hacettepe University, Ankara, Turkey.
Emiralioglu N; Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Pekcan S; Pediatric Pulmonology, Meram Medicine Faculty, Necmettin Erbakan University, Konya, Turkey.
Tana Aslan A; Pediatric Pulmonology, Gazi University Faculty of Medicine, Ankara, Turkey.
Yalcin E; Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Dogru D; Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Ozcelik U; Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Kiper N; Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Źródło:: Pediatric pulmonology [Pediatr Pulmonol] 2021 May; Vol. 56 (5), pp. 1060-1068. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji:: Journal Article; Multicenter Study
Język:: English
Imprint Name(s):: Publication: <2005-> : Hoboken, NJ : Wiley-Liss
Original Publication: [Philadelphia, PA] : W.B. Saunders, [c1985-
MeSH Terms:: Hemosiderosis*
Lung Diseases*
Adolescent ; Child ; Child, Preschool ; Humans ; Infant ; Retrospective Studies ; Risk Factors ; Hemosiderosis, Pulmonary
References:: Bakalli I, Kota L, Sala D, et al. Idiopathic pulmonary hemosiderosis-a diagnostic challenge. Ital J Pediatr. 2014;40:35.
Kjellman B, Elinder G, Garwicz S, Svan H. Idiopathic pulmonary haemosiderosis in Swedish children. Acta Paediatr Scand. 1984;73(5):584-588.
Ioachimescu OC, Sieber S, Kotch A. Idiopathic pulmonary haemosiderosis revisited. Eur Respir J. 2004;24(1):162-170.
Zhang X, Wang L, Lu A, Zhang M. Clinical study of 28 cases of paediatric idiopathic pulmonary haemosiderosis. J Trop Pediatr. 2010;56(6):386-390.
Kiper N, Gocmen A, Ozcelik U, Dilber E, Anadol D. Long-term clinical course of patients with idiopathic pulmonary hemosiderosis (1979-1994): prolonged survival with low-dose corticosteroid therapy. Pediatr Pulmonol. 1999;27(3):180-184.
Kamienska E, Urasinski T, Gawlikowska-Sroka A, Glura B, Pogorzelski A. Idiopathic pulmonary hemosiderosis in a 9-year-old girl. Eur J Med Res. 2009;14(Suppl 4):112-115.
AlJassmi AM. Autoimmunity and delayed diagnosis in pediatric idiopathic pulmonary hemosiderosis. J Pediatr Hematol Oncol. 2019;42:e240-e243.
Bhatia S, Tullu MS, Vaideeswar P, Lahiri KR. Idiopathic pulmonary hemosiderosis: alveoli are an answer to anemia. J Postgrad Med. 2011;57(1):57-60.
Pedersen FM, Milman N. Idiopathic pulmonary hemosiderosis. Ugeskr Laeger. 1996;158(7):902-904.
Moissidis I, Chaidaroon D, Vichyanond P, Bahna SL. Milk-induced pulmonary disease in infants (Heiner syndrome). Pediatr Allergy Immunol. 2005;16(6):545-552.
Corrin B, Jagusch M, Dewar A, et al. Fine structural changes in idiopathic pulmonary haemosiderosis. J Pathol. 1987;153(3):249-256.
Chin CI, Kohn SL, Keens TG, Margetis MF, Kato RM. A physician survey reveals differences in management of idiopathic pulmonary hemosiderosis. Orphanet J Rare Dis. 2015;10:98.
Alimi A, Taytard J, Abou Taam R, et al. Pulmonary hemosiderosis in children with Down syndrome: a national experience. Orphanet J Rare Dis. 2018;13(1):60.
Saeed MM, Woo MS, MacLaughlin EF, Margetis MF, Keens TG. Prognosis in pediatric idiopathic pulmonary hemosiderosis. Chest. 1999;116(3):721-725.
Kurland G, Deterding RR, Hagood JS, et al. An official American Thoracic Society clinical practice guideline: classification, evaluation, and management of childhood interstitial lung disease in infancy. Am J Respir Crit Care Med. 2013;188(3):376-394.
Clement A, de Blic J, Epaud R, et al. Management of children with interstitial lung diseases: the difficult issue of acute exacerbations. Eur Respir J. 2016;48(6):1559-1563.
Zhang Y, Luo F, Wang N, Song Y, Tao Y. Clinical characteristics and prognosis of idiopathic pulmonary hemosiderosis in pediatric patients. J Int Med Res. 2019;47(1):293-302.
Ohga S, Takahashi K, Miyazaki S, Kato H, Ueda K. Idiopathic pulmonary haemosiderosis in Japan: 39 possible cases from a survey questionnaire. Eur J Pediatr. 1995;154(12):994-995.
Morgan PG, Turner-Warwick M. Pulmonary haemosiderosis and pulmonary haemorrhage. Br J Dis Chest. 1981;75(3):225-242.
Pinar G, Kaplan S, Pinar T, et al. The prevalence and risk factors for osteoporosis among 18- to 49-year-old Turkish women. Women Health. 2017;57(9):1080-1097.
Taytard J, Nathan N, de Blic J, et al. New insights into pediatric idiopathic pulmonary hemosiderosis: the French RespiRare(R) cohort. Orphanet J Rare Dis. 2013;8:161.
Matsaniotis N, Karpouzas J, Apostolopoulou E, Messaritakis J. Idiopathic pulmonary haemosiderosis in children. Arch Dis Child. 1968;43(229):307-309.
Beckerman RC, Taussig LM, Pinnas JL. Familial idiopathic pulmonary hemosiderosis. Am J Dis Child. 1979;133(6):609-611.
Gencer M, Ceylan E, Bitiren M, Koc A. Two sisters with idiopathic pulmonary hemosiderosis. Can Respir J. 2007;14(8):490-493.
Dearborn DG, Yike I, Sorenson WG, Miller MJ, Etzel RA. Overview of investigations into pulmonary hemorrhage among infants in Cleveland, Ohio. Environ Health Perspect. 1999;107(suppl 3):495-499.
Hossain MA, Ahmed MS, Ghannoum MA. Attributes of Stachybotrys chartarum and its association with human disease. J Allergy Clin Immunol. 2004;113(2):200-208.
Willms H, Gutjahr K, Juergens UR, et al. Diagnostics and therapy of idiopathic pulmonary hemosiderosis. Med Klin. 2007;102(6):445-450.
Poggi V, Lo Vecchio A, Menna F, Menna G. Idiopathic pulmonary hemosiderosis: a rare cause of iron-deficiency anemia in childhood. J Pediatr Hematol Oncol. 2011;33(4):e160-e162.
Afzal N, Mushtaq A, Rahman A, Qureshi S. Idiopathic pulmonary haemosiderosis presenting as severe iron deficiency anaemia-a case from Pakistan. J Pak Med Assoc. 2012;62(8):845-847.
de Silva C, Mukherjee A, Jat KR, Lodha R, Kabra SK. Pulmonary hemorrhage in children: etiology, clinical profile and outcome. Indian J Pediatr. 2019;86(1):7-11.
Luo XQ, Ke ZY, Huang LB, et al. Maintenance therapy with dose-adjusted 6-mercaptopurine in idiopathic pulmonary hemosiderosis. Pediatr Pulmonol. 2008;43(11):1067-1071.
Reading R, Watson JG, Platt JW, Bird AG. Pulmonary haemosiderosis and gluten. Arch Dis Child. 1987;62(5):513-515.
Clainche LL, Bourgeois ML, Fauroux B, et al. Long-term outcome of idiopathic pulmonary hemosiderosis in children. Medicine. 2000;79(5):318-326.
Lemley DE, Katz P. Rheumatoid-like arthritis presenting as idiopathic pulmonary hemosiderosis: a report and review of the literature. J Rheumatol. 1986;13(5):954-957.
Berger N, Nichols J, Datta D. Idiopathic pulmonary haemosiderosis with celiac disease (Lane-Hamilton syndrome) in an adult-a case report. Clin Respir J. 2016;10(5):661-665.
Lane DJ, Hamilton WS. Idiopathic steatorrhoea and idiopathic pulmonary haemosiderosis. Br Med J. 1971;2(5753):89-90.
Sethi GR, Singhal KK, Puri AS, Mantan M. Benefit of gluten-free diet in idiopathic pulmonary hemosiderosis in association with celiac disease. Pediatr Pulmonol. 2011;46(3):302-305.
Chryssanthopoulos C, Cassimos C, Panagiotidou C. Prognostic criteria in idiopathic pulmonary hemosiderosis in children. Eur J Pediatr. 1983;140(2):123-125.
Kabra SK, Bhargava S, Lodha R, Satyavani A, Walia M. Idiopathic pulmonary hemosiderosis: clinical profile and follow up of 26 children. Indian Pediatr. 2007;44(5):333-338.
Blanco A, Solis P, Gomez S, Valbuena C, Telleria JJ. Antineutrophil cytoplasmic antibodies (ANCA) in idiopathic pulmonary hemosiderosis. Pediatr Allergy Immunol. 1994;5(4):235-239.
Didier K, Bolko L, Giusti D, et al. Autoantibodies associated with connective tissue diseases: what meaning for clinicians? Front Immunol. 2018;9:541.
Contributed Indexing:: Keywords: anemia; children; hemoptysis; interstitial lung disease
Entry Date(s):: Date Created: 20201128 Date Completed: 20211020 Latest Revision: 20231213
Update Code:: 20240105
DOI:: 10.1002/ppul.25189
PMID:: 33247613
: Czasopismo naukowe

Full Text Finder

Objectives: To evaluate the risk factors of recurrent pulmonary exacerbation and poor prognosis in children with idiopathic pulmonary hemosiderosis (IPH).
Methods: In this multicenter study, 54 patients with a diagnosis of IPH were included. Medical records were retrospectively reviewed from three tertiary care hospitals between 1979 and 2019. Also, current information and the long-term progress of patients was determined by contacting the families by telephone.
Results: A total of 54 children were included. The median age of onset of symptoms was 4.5 years (3 months to 15.8 years). The median time from onset to diagnosis was 0.9 years (0.25 months to 12 years). The mean number of recurrent episodes per child in the recurrence-positive group was 3.55 (1-15). Univariate analysis demonstrated that patients presenting with hypoxia or requiring transfusion at the time of presentation had significantly more recurrence episodes (p = .002). Multivariate analysis showed that the presence of hypoxia at the time of initial presentation was a significant independent predictor of recurrent episodes (p = .027). The median follow-up was 3.3 years (0.75 months to 27 years). There was a significant relationship between the presence of hypoxia, transfusion history, antinuclear antibody positivity, and elevated transaminases at the time of initial evaluation and treatment response.
Conclusions: The present study provides substantial information regarding factors that may affect recurrent exacerbations and prognosis in children with IPH. Demonstrating hypoxia as an independent risk factor in recurrence episodes could guide physicians in the planning of treatment strategies.
(© 2020 Wiley Periodicals LLC.)

Informacja