Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin.

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Abstrakt

Tytuł:: Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin.
Autorzy:: Yadouleton A
Sander AL
Moreira-Soto A
Tchibozo C
Hounkanrin G
Badou Y
Fischer C
Krause N
Akogbeto P
de Oliveira Filho EF
Dossou A
Brünink S
Aïssi MAJ
Djingarey MH
Hounkpatin B
Nagel M
Drexler JF
Źródło:: Emerging infectious diseases [Emerg Infect Dis] 2021 Jan; Vol. 27 (1). Date of Electronic Publication: 2020 Dec 01.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995-
MeSH Terms:: Serologic Tests*
Antibodies, Viral/*blood
COVID-19/*diagnosis
SARS-CoV-2/*immunology
Benin ; COVID-19/blood ; COVID-19/virology ; Humans ; Sensitivity and Specificity
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Contributed Indexing:: Keywords: Benin; COVID-19; SARS; SARS-CoV-2; West Africa; coronavirus; coronavirus disease; malaria; parasites; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses
Substance Nomenclature:: 0 (Antibodies, Viral)
Entry Date(s):: Date Created: 20201202 Date Completed: 20210105 Latest Revision: 20231110
Update Code:: 20240105
PubMed Central ID:: PMC7774555
DOI:: 10.3201/eid2701.203281
PMID:: 33261717
: Czasopismo naukowe

Pełny tekst

We used commercially available ELISAs to test 68 samples from coronavirus disease cases and prepandemic controls from Benin. We noted <25% false-positive results among controls, likely due to unspecific immune responses elicited by acute malaria. Serologic tests must be carefully evaluated to assess coronavirus disease spread and immunity in tropical regions.

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