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Tytuł:
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Neuroendocrine carcinoma of the nasal cavity with epiphora as the first symptom: A case report.
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Autorzy:
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Wu W; Department of Ocular Oncology and Ocular Trauma, Affiliated Eye Hospital of Nanchang University, Jiangxi Research Institute of Ophthalmology and Visual Sciences, Key Laboratory of Ophthalmology of Jiangxi province.; Medical Department of Graduate School, Nanchang University, Nanchang, Jiangxi, China.
Gan P; Department of Ocular Oncology and Ocular Trauma, Affiliated Eye Hospital of Nanchang University, Jiangxi Research Institute of Ophthalmology and Visual Sciences, Key Laboratory of Ophthalmology of Jiangxi province.
Xu Q; Department of Ocular Oncology and Ocular Trauma, Affiliated Eye Hospital of Nanchang University, Jiangxi Research Institute of Ophthalmology and Visual Sciences, Key Laboratory of Ophthalmology of Jiangxi province.
Wang Y; Department of Ocular Oncology and Ocular Trauma, Affiliated Eye Hospital of Nanchang University, Jiangxi Research Institute of Ophthalmology and Visual Sciences, Key Laboratory of Ophthalmology of Jiangxi province.
Liao H; Department of Ocular Oncology and Ocular Trauma, Affiliated Eye Hospital of Nanchang University, Jiangxi Research Institute of Ophthalmology and Visual Sciences, Key Laboratory of Ophthalmology of Jiangxi province.
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Źródło:
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Medicine [Medicine (Baltimore)] 2020 Dec 04; Vol. 99 (49), pp. e23502.
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Typ publikacji:
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Case Reports; Journal Article
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Język:
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English
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Imprint Name(s):
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Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
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MeSH Terms:
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Nasal Cavity*
Carcinoma, Neuroendocrine/*diagnosis
Lacrimal Apparatus Diseases/*diagnosis
Nose Neoplasms/*diagnosis
Carcinoma, Neuroendocrine/complications ; Diagnosis, Differential ; Fatal Outcome ; Female ; Humans ; Lacrimal Apparatus Diseases/etiology ; Middle Aged ; Nose Neoplasms/complications
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References:
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Entry Date(s):
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Date Created: 20201208 Date Completed: 20201223 Latest Revision: 20221005
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Update Code:
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20240104
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PubMed Central ID:
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PMC7717802
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DOI:
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10.1097/MD.0000000000023502
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PMID:
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33285758
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Rationale: Neuroendocrine carcinomas (NECs) are rare malignancies that originate from the hormone-producing cells of the neuroendocrine system. They can grow in most organs of the body but are commonly found in the gastrointestinal and respiratory tracts. The nasal cavity is a rare site for NECs.
Patient Concerns: We report a case of NECs in a 45-year-old woman who presented with epiphora in the right eye for a year owing to an unknown reason.
Diagnoses: The diagnosis was initially confirmed via histological and immunohistochemical assays. Postoperatively, computed tomography of the neck revealed C4 vertebral bone metastasis.
Interventions: The tumor was endoscopically removed from the right eye. The patient received a full course of adjuvant polychemotherapy.
Outcomes: Six months after diagnosis, the patient died due to bone metastasis.
Lessons: Diagnosing nasal neuroendocrine carcinoma is clinically challenging. It must be distinguished from other orbital masses, such as chronic dacryocystitis or nasal polyps. The treatment should be further investigated for this rare malignancy in near future.
