Tytuł pozycji:
Provision of acute renal replacement therapy, using three separate modalities, in critically ill patients during the COVID-19 pandemic. An after action review from a UK tertiary critical care centre.
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Tytuł:
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Provision of acute renal replacement therapy, using three separate modalities, in critically ill patients during the COVID-19 pandemic. An after action review from a UK tertiary critical care centre.
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Autorzy:
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Fisher R; Department of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: .
Clarke J; Department of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: .
Al-Arfi K; Department of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: .
Saha R; Department of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: .
Lioudaki E; King's Kidney Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: .
Mehta R; Department of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: .
Pahl C; Department of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: .
Sharpe C; King's Kidney Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: .
Bramham K; King's Kidney Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: .
Hutchings S; Department of Critical Care, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: .
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Źródło:
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Journal of critical care [J Crit Care] 2021 Apr; Vol. 62, pp. 190-196. Date of Electronic Publication: 2020 Dec 28.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: Philadelphia Pa : W.B. Saunders
Original Publication: Orlando, FL : Grune & Stratton, c1986-
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MeSH Terms:
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Acute Kidney Injury/*etiology
Acute Kidney Injury/*therapy
COVID-19/*complications
Critical Care/*methods
Renal Replacement Therapy/*methods
Adult ; Aged ; Continuous Renal Replacement Therapy/methods ; Female ; Humans ; Intensive Care Units ; Intermittent Renal Replacement Therapy/methods ; Male ; Middle Aged ; Peritoneal Dialysis/statistics & numerical data ; Retrospective Studies ; SARS-CoV-2 ; Tertiary Care Centers ; United Kingdom/epidemiology
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References:
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Contributed Indexing:
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Keywords: Acute kidney injury; COVID-19; Haemodialysis; Peritoneal Dialysis; Renal replacement therapy
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Entry Date(s):
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Date Created: 20210110 Date Completed: 20210402 Latest Revision: 20221221
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Update Code:
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20240105
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PubMed Central ID:
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PMC7837302
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DOI:
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10.1016/j.jcrc.2020.12.023
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PMID:
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33422809
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Purpose: The aim of this study is to describe the incidence of Acute Kidney Injury (AKI) amongst patients admitted to the Intensive Care Unit (ICU) with COVID-19. In addition we aim to detail the range of Renal Replacement Therapy (RRT) modalities offered to these patients (including peritoneal dialysis - PD - and intermittent haemodialysis - IHD) in order to meet demand during pandemic conditions.
Materials and Methods: Single-centre retrospective case note review of adult patients with confirmed COVID-19 admitted to ICU.
Results: Amongst 136 patients without a prior history of End Stage Kidney Disease (ESKD), 108 (79%) developed AKI and 63% of admitted patients received RRT. Due to resource limitations the range of RRT options were expanded from solely Continuous Veno-Venous HaemoDiaFiltration (CVVHDF - our usual standard of care) to include PD (in 35 patients) and IHD (in 15 patients). During the study period the proportion of RRT provided within ICU as CVVHDF fell from 100% to a nadir of 39%. There were no significant complications of either PD or IHD.
Conclusions: During periods of resource limitations PD and IHD can safely be used to reduce dependence on CVVHDF in select patients with AKI secondary to COVID-19.
Competing Interests: Declaration of Competing Interest All authors declare: no support from any organisation for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work; no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2021. Published by Elsevier Inc.)
