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Tytuł pozycji:

Distribution of haemoglobin genotypes, knowledge, attitude and practices towards sickle cell disease among unmarried youths in the Buea Health District, Cameroon.

Tytuł:
Distribution of haemoglobin genotypes, knowledge, attitude and practices towards sickle cell disease among unmarried youths in the Buea Health District, Cameroon.
Autorzy:
Ngwengi NY; Department of Medicine, Faculty of Health Sciences, University of Buea, Buea, South West Region, Cameroon.
Fon PN; Department of Medicine, Faculty of Health Sciences, University of Buea, Buea, South West Region, Cameroon.
Mbanya D; Faculty of Health Sciences, University of Bamenda, Bamenda, Cameroun.; Haematology & Blood Transfusion Service, Yaoundé University Teaching Hospital, Yaoundé, Cameroon.
Źródło:
The Pan African medical journal [Pan Afr Med J] 2020 Oct 01; Vol. 37, pp. 109. Date of Electronic Publication: 2020 Oct 01 (Print Publication: 2020).
Typ publikacji:
Journal Article
Język:
English
Imprint Name(s):
Original Publication: Kampala, Uganda : African Field Epidemiology Network
MeSH Terms:
Health Knowledge, Attitudes, Practice*
Anemia, Sickle Cell/*epidemiology
Hemoglobins/*genetics
Sickle Cell Trait/*epidemiology
Adolescent ; Adult ; Anemia, Sickle Cell/genetics ; Cameroon ; Cross-Sectional Studies ; Educational Status ; Female ; Genotype ; Humans ; Male ; Prevalence ; Sickle Cell Trait/genetics ; Single Person ; Surveys and Questionnaires ; Young Adult
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Contributed Indexing:
Keywords: Haemoglobin; attitude; knowledge; practice; sickle cell disease
Substance Nomenclature:
0 (Hemoglobins)
Entry Date(s):
Date Created: 20210111 Date Completed: 20210119 Latest Revision: 20220419
Update Code:
20240105
PubMed Central ID:
PMC7757270
DOI:
10.11604/pamj.2020.37.109.17864
PMID:
33425142
Czasopismo naukowe
Introduction: sickle cell disease (SCD) is one of the commonest genetic causes of morbidity and mortality in the world. In resource-limited settings, SCD prevention through public education and screening could be a significant strategy to curb its prevalence. The study aimed at determining the distribution of haemoglobin genotypes among unmarried youths in Buea, Cameroon as well as their knowledge, attitude and practices towards SCD.
Methods: a community-based, analytic, cross-sectional study was conducted within the city of Buea. Data was collected from 410 youths using self-administered questionnaires. Of the 410 youths, 100 were selected by purposive random sampling and their haemoglobin genotyping was done using haemoglobin electrophoresis. The data was analysed using the statistical software Epi Info Version 7.
Results: the majority (51.5%) of the 410 respondents were females. The modal age range was 18- 21 years (46.8%) and 60.4% had tertiary education. Less than one quarter (20.5%) had good knowledge of SCD. Only 13.2% knew their genotype and 59.3% were willing to avoid carrier marriages. Out of the 100 participants for genotyping, 84.0% had normal haemoglobin (HbAA) and 16.0% had the sickle cell trait (HbAS).
Conclusion: most of the respondents had moderate knowledge of SCD. Only a few knew their haemoglobin genotype and more than half were willing to avoid carrier marriages. The prevalence of sickle cell trait is high in Buea. The promotion of preventive methods like public education and genetic screening is recommended to reduce the burden of SCD in Cameroon.
Competing Interests: The authors declare no competing interests.
(Copyright: Nini Yesih Ngwengi et al.)

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