Factors associated with the Severity of Findings on Hepatic Transient Elastography among Persons with Type 2 Diabetes and Fatty Liver.

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Tytuł:: Factors associated with the Severity of Findings on Hepatic Transient Elastography among Persons with Type 2 Diabetes and Fatty Liver.
Autorzy:: Fernando JN; Section of Endocrinology, Diabetes and Metabolism, Chinese General Hospital and Medical Center, Philippines.
Alba RL; Section of Endocrinology, Diabetes and Metabolism, Chinese General Hospital and Medical Center, Philippines.
Alba W; Section of Gastroenterology, Chinese General Hospital and Medical Center, Philippines.
Źródło:: Journal of the ASEAN Federation of Endocrine Societies [J ASEAN Fed Endocr Soc] 2019; Vol. 34 (2), pp. 134-143. Date of Electronic Publication: 2019 Nov 10.
Typ publikacji:: Journal Article
Język:: English
Imprint Name(s):: Publication: Philippines : ASEAN Federation of Endocrine Societies
Original Publication: [Bangkok, Thailand] : The Society,
References:: World J Hepatol. 2016 Nov 28;8(33):1459-1465. (PMID: 27957244)
Am J Med. 2003 Nov;115(7):554-9. (PMID: 14599635)
Clin Res Hepatol Gastroenterol. 2012 Feb;36(1):13-20. (PMID: 21920839)
Hepatology. 1995 Dec;22(6):1714-9. (PMID: 7489979)
Hepatology. 2018 Jan;67(1):328-357. (PMID: 28714183)
J Assoc Physicians India. 2009 Mar;57:205-10. (PMID: 19588648)
Gastroenterology. 1999 Jun;116(6):1413-9. (PMID: 10348825)
Gut. 2010 Jul;59(7):969-74. (PMID: 20581244)
Hepatology. 2004 Oct;40(4):820-6. (PMID: 15382171)
Diabetes Metab Syndr Obes. 2015 Apr 23;8:213-8. (PMID: 25960672)
Hepatology. 2010 Feb;51(2):454-62. (PMID: 20101745)
Diabetes Care. 2017 Mar;40(3):419-430. (PMID: 28223446)
Clin Gastroenterol Hepatol. 2004 Mar;2(3):262-5. (PMID: 15017611)
Gastroenterology. 2011 Jan;140(1):124-31. (PMID: 20858492)
Gut. 2007 Jul;56(7):968-73. (PMID: 17255218)
J Hepatol. 2005 Jan;42(1):132-8. (PMID: 15629518)
Hepatology. 1990 Nov;12(5):1106-10. (PMID: 2227807)
Liver Int. 2017 Dec;37(12):1897-1906. (PMID: 28556413)
Obes Facts. 2016;9(2):65-90. (PMID: 27055256)
Acta Med Indones. 2017 Apr;49(2):91-98. (PMID: 28790222)
Gut. 2004 May;53(5):750-5. (PMID: 15082596)
Hepatology. 2006 Oct;44(4):865-73. (PMID: 17006923)
Aliment Pharmacol Ther. 2011 Aug;34(3):274-85. (PMID: 21623852)
Liver Int. 2009 Jan;29(1):113-9. (PMID: 18384521)
Int J Chron Obstruct Pulmon Dis. 2017 Aug 21;12:2465-2475. (PMID: 28860741)
Ann Med. 2011 Dec;43(8):617-49. (PMID: 21039302)
Contributed Indexing:: Keywords: NAFLD; transient elastography; type 2 diabetes
Entry Date(s):: Date Created: 20210114 Latest Revision: 20220419
Update Code:: 20240105
PubMed Central ID:: PMC7784217
DOI:: 10.15605/jafes.034.02.03
PMID:: 33442148
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Objective: This study aims to determine the relationship between the different factors associated with the severity of Fibroscan with CAP findings among patients with Type 2 diabetes and fatty liver.
Methodology: This is a cross-sectional study. Seven hundred four Fibroscan with Controlled Attenuation Parameter (CAP) results were electronically retrieved from a diagnostic center. 285 charts of diabetic patients with fatty liver on ultrasound were reviewed. 164 patients with fatty liver on ultrasound and Fibroscan with CAP were included in the study. Several factors were analysed in relation to the severity of Fibroscan with CAP findings in the study group.
Results: Fifty five point five percent (55.5%) (91/164) had significant fibrosis and cirrhosis. Hepatic steatosis prevalence was 96% (158/164). Diabetes >5 years (OR 1.75), HbA1c >7% (OR 2.25) and high SGPT levels (OR 2.39) were associated with liver fibrosis and cirrhosis. BMI >25 kg/m2 (OR 1.45), triglyceride levels >150 mg/dl (OR 1.31) and HbA1c >7% (OR 1.74) were associated with hepatic steatosis.
Conclusion: Factors associated with the severity of hepatic fibrosis, cirrhosis and steatosis included above normal BMI, disease duration of >5 years, poor glycemic control and elevated levels of ALT, and serum triglycerides.
Competing Interests: The authors declare no conflict of interest.
(© 2019 Journal of the ASEAN Federation of Endocrine Societies.)

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