Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ
Tytuł pozycji:

Reduced skeletal muscle endurance and ventilatory efficiency during exercise in adult smokers without airflow obstruction.

Tytuł :
Reduced skeletal muscle endurance and ventilatory efficiency during exercise in adult smokers without airflow obstruction.
Autorzy :
Sadaka AS; National Heart and Lung Institute, Imperial College London, United Kingdom.
Faisal A; Department of Sport and Exercise Sciences, Manchester Metropolitan University, United Kingdom.
Khalil YM; Faculty of Medicine, Chest Department, Alexandria University, Egypt.
Mourad SM; Faculty of Medicine, Chest Department, Alexandria University, Egypt.
Zidan MH; Faculty of Medicine, Chest Department, Alexandria University, Egypt.
Polkey MI; Respiratory Medicine, Royal Brompton & Harefield NHS Foundation Trust, United Kingdom.
Hopkinson NS; National Heart and Lung Institute, Imperial College London, United Kingdom.
Pokaż więcej
Źródło :
Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2021 Jan 14. Date of Electronic Publication: 2021 Jan 14.
Publication Model :
Ahead of Print
Typ publikacji :
Journal Article
Język :
English
Imprint Name(s) :
Original Publication: Bethesda, MD : American Physiological Society, c1985-
Contributed Indexing :
Keywords: EXERCISE; MAGNETIC STIMULATION; SKELETAL MUSCLE; SMOKING; VENTILATORY INEFFICIENCY
Entry Date(s) :
Date Created: 20210114 Latest Revision: 20210211
Update Code :
20210218
DOI :
10.1152/japplphysiol.00762.2020
PMID :
33444125
Czasopismo naukowe
Background: Smokers without airflow obstruction have reduced exercise capacity, but the underlying physiological mechanisms are not fully understood.
Aim: To compare quadriceps function assessed using non-volitional measures, and ventilatory requirements during exercise, between smokers without airway obstruction and never-smoker controls.
Study Design and Methods: Adult smokers (n=20) and never-smoker controls (n=16) aged 25-50 years with normal spirometry, underwent incremental cycle cardiopulmonary exercise testing to exhaustion with measurement of symptoms and dynamic lung volumes. Quadriceps strength and endurance were assessed non-volitionally using single and repetitive magnetic stimulation. Quadriceps bulk was assessed using ultrasound, as rectus-femoris cross-sectional area (Q RF -CSA). Physical activity level was quantified using the SenseWear TM armband worn for 5 days.
Results: Smokers had lower peak exercise workload, peak oxygen consumption and anaerobic threshold (AT) compared to controls (170+46 vs. 256+57 W; 2.20 ±0.56 vs. 3.18 ±0.72 L/min; 1.38±0.33 vs. 2.09±0.7 L/min, respectively; p<0.01 for all). Quadriceps endurance was lower in smokers (D force-time integral 54.9±14.7% vs. 40.4±14.7%; p=0.007), but physical activity, quadriceps strength and bulk were similar between groups. Smokers displayed higher ventilation (120W: 52.6±11.8 vs. 40.7±6.0 L/min; p<0.001), decreased ventilatory efficiency (higher ⩒ E /⩒CO 2 ) and were more breathless with greater leg fatigue at iso-workloads and iso-ventilation levels compared to never-smoker controls. Smokers showed no mechanical constraints on tidal volume expansion during exercise or ventilatory limitation at peak exercise.
Conclusion: Adult smokers without airflow obstruction have reduced skeletal muscle endurance and ventilatory efficiency compared to never-smoker controls, despite similar daily physical activity levels, which contributed to reduced peak exercise capacity.

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies