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Tytuł:
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Biocatalysis in Green and Blue: Cyanobacteria.
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Autorzy:
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Jodlbauer J; Institute of Applied Synthetic Chemistry, TU Wien, Getreidemarkt 9/OC-163, 1060 Vienna, Austria.
Rohr T; Institute of Applied Synthetic Chemistry, TU Wien, Getreidemarkt 9/OC-163, 1060 Vienna, Austria.
Spadiut O; Institute of Chemical Engineering, research area Biochemical Engineering, TU Wien, Gumpendorfer Strasse 1a, 1060 Vienna, Austria.
Mihovilovic MD; Institute of Applied Synthetic Chemistry, TU Wien, Getreidemarkt 9/OC-163, 1060 Vienna, Austria.
Rudroff F; Institute of Applied Synthetic Chemistry, TU Wien, Getreidemarkt 9/OC-163, 1060 Vienna, Austria. Electronic address: .
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Źródło:
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Trends in biotechnology [Trends Biotechnol] 2021 Sep; Vol. 39 (9), pp. 875-889. Date of Electronic Publication: 2021 Jan 16.
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Typ publikacji:
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Journal Article; Review
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Język:
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English
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Imprint Name(s):
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Publication: Barking : Elsevier Science Publishers
Original Publication: [Amsterdam, Netherlands : Elsevier Science Publishers B.V. (Biomedical Division), c1983-
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MeSH Terms:
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Biocatalysis*
Biotechnology*/trends
Cyanobacteria*/metabolism
Biotransformation ; Photosynthesis ; Research/trends
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Contributed Indexing:
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Keywords: cyanobacteria; industrial application; photobiocatalysis; photosynthesis; phototrophic metabolism; whole-cell biotransformation
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Entry Date(s):
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Date Created: 20210120 Date Completed: 20211012 Latest Revision: 20211012
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Update Code:
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20240105
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DOI:
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10.1016/j.tibtech.2020.12.009
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PMID:
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33468423
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Recently, several studies have proven the potential of cyanobacteria as whole-cell biocatalysts for biotransformation. Compared to heterotrophic hosts, cyanobacteria show unique advantages thanks to their photoautotrophic metabolism. Their ability to use light as energy and CO 2 as carbon source promises a truly sustainable production platform. Their photoautotrophic metabolism offers an encouraging source of reducing power, which makes them attractive for redox-based biotechnological purposes. To exploit the full potential of these whole-cell biocatalysts, cyanobacterial cells must be considered in their entirety. With this emphasis, this review summarizes the latest developments in cyanobacteria research with a strong focus on the benefits associated with their unique metabolism. Remaining bottlenecks and recent strategies to overcome them are evaluated for their potential in future applications.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
