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Tytuł:
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Frequency and types of haemoglobinopathies in children with microcytic anaemia.
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Autorzy:
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Khan SA; Department of Pediatrics, Shifa College of Medicine, Shifa international Hospital, Islamabad, Pakistan.
Aaraj S; Department of Pediatrics, Shifa College of Medicne, Islamabad, Pakistan.
Hussain SNF; Final Year Student, Shifa College of Medicine, Islamabad, Pakistan.
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Źródło:
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JPMA. The Journal of the Pakistan Medical Association [J Pak Med Assoc] 2021 Jan; Vol. 71 (1(A)), pp. 78-80.
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Typ publikacji:
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Journal Article
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Język:
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English
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Imprint Name(s):
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Publication: Karachi : Pakistan Medical Association
Original Publication: Karachi.
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MeSH Terms:
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Anemia, Hypochromic*
Anemia, Iron-Deficiency*/epidemiology
Hemoglobinopathies*/complications
Hemoglobinopathies*/epidemiology
Child ; Female ; Humans ; Pakistan/epidemiology ; Pregnancy ; Prospective Studies
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Contributed Indexing:
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Keywords: Haemoglobinopathy, Iron deficiency anaemia, Microcytic, MCV, IDA.
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Entry Date(s):
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Date Created: 20210123 Date Completed: 20210514 Latest Revision: 20220420
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Update Code:
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20240105
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DOI:
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10.47391/JPMA.589
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PMID:
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33484524
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Objective: To study the frequency and types of haemoglobinopathies in children with microcytic anaemia.
Methods: The prospective study was conducted at the Paediatric Out-patient Department of Shifa Falahi Community Health Centre, Islamabad, Pakistan, from July to December, 2018, and comprised patients aged from 3 months to 14 years who had haemoglobin <10mg/dl and mean corpuscular volume <70fL. Serum ferritin and haemoglobin electrophoresis were done to check for iron deficiency anaemia and haemoglobinopathies. Data was analysed using SPSS 23.
Results: Of 175 subjects, 33(18.9%) had haemoglobinopathies and 142(81.1%) had iron deficiency anaemia. Thalassemia trait 18(10.3%) was the leading cause amongst haemoglobinopathies, followed by thalassemia major 8(4.6 %) and intermedia 5(2.9%). There were 2(1.1%) patients with haemoglobin D.
Conclusions: The prevalence of haemoglobinopathies was high. Identification of haemoglobinopathies is important for proper treatment, antenatal screening and future genetic counselling.
