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Tytuł pozycji:

Type II methanotrophs: A promising microbial cell-factory platform for bioconversion of methane to chemicals.

Tytuł :
Type II methanotrophs: A promising microbial cell-factory platform for bioconversion of methane to chemicals.
Autorzy :
Nguyen DTN; Department of Chemical Engineering (Integrated Engineering), Kyung Hee University, Gyeonggi-do 17104, Republic of Korea.
Lee OK; Department of Chemical Engineering (Integrated Engineering), Kyung Hee University, Gyeonggi-do 17104, Republic of Korea.
Nguyen TT; Department of Chemical Engineering (Integrated Engineering), Kyung Hee University, Gyeonggi-do 17104, Republic of Korea.
Lee EY; Department of Chemical Engineering (Integrated Engineering), Kyung Hee University, Gyeonggi-do 17104, Republic of Korea. Electronic address: .
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Źródło :
Biotechnology advances [Biotechnol Adv] 2021 Mar-Apr; Vol. 47, pp. 107700. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
Język :
English
Imprint Name(s) :
Publication: Oxford : Elsevier Science
Original Publication: Oxford ; New York : Pergamon Press, c1983-
MeSH Terms :
Biofuels*
Methane*
Acetyl Coenzyme A ; Biotechnology ; Metabolic Engineering
Contributed Indexing :
Keywords: Bioconversion*; Biofuels and chemicals*; Metabolic engineering*; Methane*; Methanotrophs*; Type II methanotrophs*
Substance Nomenclature :
0 (Biofuels)
72-89-9 (Acetyl Coenzyme A)
OP0UW79H66 (Methane)
Entry Date(s) :
Date Created: 20210206 Date Completed: 20210426 Latest Revision: 20210426
Update Code :
20210427
DOI :
10.1016/j.biotechadv.2021.107700
PMID :
33548453
Czasopismo naukowe
Methane, the predominant element in natural gas and biogas, represents a promising alternative to carbon feedstocks in the biotechnological industry due to its low cost and high abundance. The bioconversion of methane to value-added products can enhance the value of gas and mitigate greenhouse gas emissions. Methanotrophs, methane-utilizing bacteria, can make a significant contribution to the production of various valuable biofuels and chemicals from methane. Type II methanotrophs in comparison with Type I methanotrophs have distinct advantages, including high acetyl-CoA flux and the co-incorporation of two important greenhouse gases (methane and CO 2 ), making it a potential microbial cell-factory platform for methane-derived biomanufacturing. Herein, we review the most recent advances in Type II methanotrophs related to multi-omics studies and metabolic engineering. Representative examples and prospects of metabolic engineering strategies for the production of suitable products are also discussed.
(Copyright © 2021 Elsevier Inc. All rights reserved.)

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