[Evolutionary Aspects of Genomic Imprinting].

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Tytuł:: [Evolutionary Aspects of Genomic Imprinting].
Autorzy:: Sazhenova EA; Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, 634050 Russia.; .
Lebedev IN; Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, 634050 Russia.
Źródło:: Molekuliarnaia biologiia [Mol Biol (Mosk)] 2021 Jan-Feb; Vol. 55 (1), pp. 3-19.
Typ publikacji:: Journal Article; Review
Język:: Russian
Imprint Name(s):: Original Publication: Moskva : Izdatelstvo Nauka
MeSH Terms:: DNA Methylation*
Genomic Imprinting*/genetics
Animals ; Female ; Mutation ; Pregnancy
Contributed Indexing:: Keywords: DNA methylation; brain; eukaryotes; evolution; genomic imprinting; placenta
Entry Date(s):: Date Created: 20210210 Date Completed: 20210212 Latest Revision: 20210212
Update Code:: 20240105
DOI:: 10.31857/S0026898420060105
PMID:: 33566022
: Czasopismo naukowe

Genomic imprinting is an epigenetic phenomenon that differentiates maternal and paternal copies of genes in the genome and causes monoallelic expression depending on parental origin. Imprinting is an evolutionary puzzle, as it bears the costs of diploidization without its advantages, namely, protection from recessive mutations. The aim of this review is to answer the question of why genomic imprinting arose and became fixed in the evolution of angiosperms, insects, marsupials, and placental mammals.

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