Evaluation of an emergency department-based opioid overdose survivor intervention: Difference-in-difference analysis of electronic health record data to assess key outcomes.

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Tytuł:: Evaluation of an emergency department-based opioid overdose survivor intervention: Difference-in-difference analysis of electronic health record data to assess key outcomes.
Autorzy:: Watson DP; Chestnut Health Systems, Lighthouse Institute, 221 W. Walton St., Chicago, IL, 60610, United States. Electronic address: .
Weathers T; Indiana University Richard M. Fairbanks School of Public Health, Department of Social and Behavioral Sciences, 1050 Wishard Blvd., Indianapolis, IN, 46202, United States. Electronic address: .
McGuire A; Richard L. Roudebush VAMC, Health Services Research and Development, 1481 W. 10th St (11H) Rm. C8108, Indianapolis, IN, 46202, United States; Indiana University Purdue University Indianapolis, Department of Psychology, 402 N. Blackford St., Indianapolis, IN, 46202, United States. Electronic address: .
Cohen A; GiveWell, 1714 Franklin Street, Oakland, CA, 94612, United States. Electronic address: .
Huynh P; Wayne State University, School of Social Work, Center for Behavioral Health and Justice, 5201 Cass Avenue Suite 226, Detroit, MI, 48202, United States. Electronic address: .
Bowes C; Indiana University School of Medicine, 340 W. 10th St., Indianapolis, IN, 46202, United States. Electronic address: .
O'Donnell D; Indiana University School of Medicine, Department of Emergency Medicine, 720 Eskenazi Ave., Indianapolis, IN, 46202, United States. Electronic address: .
Brucker K; SB Emergency Physicians, South Bend, IN, United States. Electronic address: .
Gupta S; Department of Economics, Indiana University Purdue University Indianapolis, United States. Electronic address: .
Źródło:: Drug and alcohol dependence [Drug Alcohol Depend] 2021 Apr 01; Vol. 221, pp. 108595. Date of Electronic Publication: 2021 Feb 15.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Język:: English
Imprint Name(s):: Publication: Limerick : Elsevier
Original Publication: Lausanne, Elsevier Sequoia.
MeSH Terms:: Electronic Health Records*
Opiate Overdose*
Adult ; Analgesics, Opioid/therapeutic use ; Drug Overdose/drug therapy ; Drug Prescriptions ; Emergency Medical Services ; Emergency Service, Hospital ; Female ; Hospitalization ; Humans ; Male ; Middle Aged ; Naloxone/therapeutic use ; Opioid-Related Disorders/drug therapy ; Survivors
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Grant Information:: K12 HL133310 United States HL NHLBI NIH HHS
Contributed Indexing:: Keywords: Difference-in-difference; Emergency medicine; Evaluation; Medication for opioid use disorder; Naloxone; Opioid use disorder; Overdose; Peer recovery coaching
Substance Nomenclature:: 0 (Analgesics, Opioid)
36B82AMQ7N (Naloxone)
Entry Date(s):: Date Created: 20210220 Date Completed: 20210528 Latest Revision: 20220402
Update Code:: 20240105
PubMed Central ID:: PMC8026710
DOI:: 10.1016/j.drugalcdep.2021.108595
PMID:: 33610095
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Background: In recent years, a number of emergency department (ED)-based interventions have been developed to provide supports and/or treatment linkage for people who use opioids. However, there is limited research supporting the effectiveness of the majority of these interventions. Project POINT is an ED-based intervention aimed at providing opioid overdose survivors with naloxone and recovery supports and connecting them to evidence-based medications for opioid use disorder (MOUD). An evaluation of POINT was conducted.
Methods: A difference-in-difference analysis of electronic health record data was completed to understand the difference in outcomes for patients admitted to the ED when a POINT staff member was working versus times when they were not. The observation window was January 1, 2012 to July 6, 2019, which included N = 1462 unique individuals, of which 802 were in the POINT arm. Outcomes of focus include MOUD opioid prescriptions dispensed, active non-MOUD opioid prescriptions dispensed, naloxone access, and drug poisonings.
Results: The POINT arm had a significant increase in MOUD prescriptions dispensed, non-MOUD prescriptions dispensed, and naloxone access (all p-values < 0.001). There was no significant effect related to subsequent drug poisoning-related hospital admissions.
Conclusions: The results support the assertion that POINT is meeting its two primary goals related to increasing naloxone access and connecting patients to MOUD. Generalization of these results is limited; however, the evaluation contributes to a nascent area of research and can serve a foundation for future work.
(Copyright © 2021 Elsevier B.V. All rights reserved.)

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