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Continental Origin for Q Haplogroup Patrilineages in Argentina and Paraguay.

Tytuł:
Continental Origin for Q Haplogroup Patrilineages in Argentina and Paraguay.
Autorzy:
Jurado Medina LS; Instituto Multidisciplinario de Biología Celular (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas de la Republica Argentina (CONICET)-Comisión de Investigaciones Científicas (CIC)-Universidad Nacional de La Plata (UNLP), La Plata, Argentina.
Paz Sepúlveda PB; Instituto Multidisciplinario de Biología Celular (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas de la Republica Argentina (CONICET)-Comisión de Investigaciones Científicas (CIC)-Universidad Nacional de La Plata (UNLP), La Plata, Argentina.
Ramallo V; Centro Nacional Patagónico, CONICET, Puerto Madryn, Argentina.
Sala C; Instituto Multidisciplinario de Biología Celular (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas de la Republica Argentina (CONICET)-Comisión de Investigaciones Científicas (CIC)-Universidad Nacional de La Plata (UNLP), La Plata, Argentina.
Beltramo J; Instituto Multidisciplinario de Biología Celular (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas de la Republica Argentina (CONICET)-Comisión de Investigaciones Científicas (CIC)-Universidad Nacional de La Plata (UNLP), La Plata, Argentina.; Laboratorio de Análisis Comparativo de ADN, Suprema Corte de Justicia de la Provincia de Buenos Aires, La Plata, Argentina.
Schwab M; Instituto Multidisciplinario de Biología Celular (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas de la Republica Argentina (CONICET)-Comisión de Investigaciones Científicas (CIC)-Universidad Nacional de La Plata (UNLP), La Plata, Argentina.
Motti JMB; Laboratorio de Ecología Evolutiva Humana, Núcleo de Estudios Interdisciplinarios de Poblaciones Humanas de Patagonia Austral-Facultad de Ciencias Sociales, Universidad Nacional del Centro de la Provincia de Buenos Aires, Quequén, Argentina.
Santos MR; Instituto Multidisciplinario de Biología Celular (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas de la Republica Argentina (CONICET)-Comisión de Investigaciones Científicas (CIC)-Universidad Nacional de La Plata (UNLP), La Plata, Argentina.
Cuello MV; Instituto Multidisciplinario de Biología Celular (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas de la Republica Argentina (CONICET)-Comisión de Investigaciones Científicas (CIC)-Universidad Nacional de La Plata (UNLP), La Plata, Argentina.
Salceda S; División Antropología, Facultad de Ciencias Naturales y Museo (FCNyM), UNLP, La Plata, Argentina.
Dipierri JE; Instituto de Biología de la Altura, Facultad de Humanidades y Ciencias Sociales, Universidad Nacional de Jujuy (UNJu), San Salvador de Jujuy, Argentina.
Alfaro Gómez EL; Instituto de Biología de la Altura, Facultad de Humanidades y Ciencias Sociales, Universidad Nacional de Jujuy (UNJu), San Salvador de Jujuy, Argentina.; Instituto de Ecorregiones Andinas, UNJu, San Salvador de Jujuy, Argentina.
Muzzio M; Instituto Multidisciplinario de Biología Celular (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas de la Republica Argentina (CONICET)-Comisión de Investigaciones Científicas (CIC)-Universidad Nacional de La Plata (UNLP), La Plata, Argentina.; FCNyM, UNLP, La Plata, Argentina.
Bravi CM; Instituto Multidisciplinario de Biología Celular (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas de la Republica Argentina (CONICET)-Comisión de Investigaciones Científicas (CIC)-Universidad Nacional de La Plata (UNLP), La Plata, Argentina.; FCNyM, UNLP, La Plata, Argentina.
Bailliet G; Instituto Multidisciplinario de Biología Celular (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas de la Republica Argentina (CONICET)-Comisión de Investigaciones Científicas (CIC)-Universidad Nacional de La Plata (UNLP), La Plata, Argentina, .
Źródło:
Human biology [Hum Biol] 2021 Feb; Vol. 92 (2), pp. 63-80.
Typ publikacji:
Journal Article
Język:
English
Imprint Name(s):
Original Publication: Detroit, MI : Wayne State University Press
MeSH Terms:
Chromosomes, Human, Y*/genetics
Genetics, Population*
Americas ; Argentina ; Asia ; Europe ; Haplotypes/genetics ; Humans ; Male ; Microsatellite Repeats ; Middle East ; Paraguay ; Phylogeny ; Polymorphism, Single Nucleotide/genetics
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Contributed Indexing:
Keywords: HAPLOGROUPS; HAPLOTYPES; SEQUENCING; SOUTH AMERICA; Y CHROMOSOME
Entry Date(s):
Date Created: 20210228 Date Completed: 20210427 Latest Revision: 20210427
Update Code:
20240105
DOI:
10.13110/humanbiology.92.2.01
PMID:
33639638
Czasopismo naukowe
Haplogroup Q originated in Eurasia around 30,000 years ago. It is present in Y-chromosomes from Asia and Europe at rather low frequencies. Since America is undoubtedly one of the continents where this haplogroup is highly represented, it has been defined as one of the founding haplogroups. Its M3 clade has been early described as the most frequent, with pan-American representation. However, it was also possible to find several other haplogroup Q clades at low frequencies. Numerous mutations have been described for haplogroup Q, allowing analysis of its variability and assignment of its geographic origin. We have analyzed 442 samples of unrelated men from Argentina and Paraguay belonging to haplogroup Q; here we report specifically on 27 Q (xM3) lineages. We tested 3 single-nucleotide polymorphisms (SNPs) by amplified product-length polymorphism (APLP) analysis, 3 SNPs for restriction fragment length polymorphism (RFLP) analysis, 15 SNPs by Sanger sequencing, and 17 short tandem repeats (STRs). Our approach allowed us to identify five subhaplogroups. Q-M3 and Q-CTS2730/Z780 are undoubtedly autochthonous lineages and represent the most frequent subhaplogroups, with significant representation in self-defined aboriginal populations, and their autochthonous status has been previously described. The aim of present work was to identify the continental origin of the remaining Q lineages. Thus, we analyzed the STR haplotypes for the samples and compared them with haplotypes described by other authors for the rest of the world. Even when haplogroup Q lineages have been extensively studied in America, some of them could have their origin in post-Columbian human migration from Europe and Middle East.

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