[From treatable to curable to eliminated ---- a decade of research progress in the diagnosis and treatment of hepatitis C].

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Tytuł:: [From treatable to curable to eliminated ---- a decade of research progress in the diagnosis and treatment of hepatitis C].
Autorzy:: Rao HY; Peking University People's Hospital, Peking University Hepatology Institute, National Clinical Research Center for Infectious Disease, Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing 100044, China.
Wei L; Hepatopancreatobiliary Center, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing 102218, China.
Źródło:: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology [Zhonghua Gan Zang Bing Za Zhi] 2021 Feb 20; Vol. 29 (2), pp. 102-107.
Typ publikacji:: Journal Article
Język:: Chinese
Imprint Name(s):: Original Publication: Chongqing Shi : Chongqing yi ke da xue, di 2 lin chuang xue yuan Bing du xing gan yan yan jiu suo,
MeSH Terms:: Hepatitis C*/drug therapy
Hepatitis C, Chronic*/diagnosis
Hepatitis C, Chronic*/drug therapy
Hepatitis C, Chronic*/epidemiology
Hepatitis, Viral, Human*
Antiviral Agents/therapeutic use ; China ; Hepacivirus/genetics ; Humans
Grant Information:: 2017ZX10202202 The 13th Five-Year Science and Technology Major Project on the Prevention and Treatment of Major Infectious Diseases
Contributed Indexing:: Keywords: Cure; Direct-acting antiviral agents; Eliminate; Hepatitis C
Local Abstract: [Publisher, Chinese] 丙型肝炎是第一个可以治愈的慢性病毒感染性疾病，人类从发现丙型肝炎病毒的基因组到具备消除该病毒的公共卫生威胁的能力，仅仅用了30年时间。近十年来，丙型肝炎的病原学检测，经历了从灵敏、定量到快速、方便、全自动、即时检验的发展。随着直接抗病毒药物的陆续上市，包括特殊人群在内的各类丙型肝炎患者能被短疗程、全口服药物安全、有效地治愈。丙型肝炎诊断和治疗研究的重要进展是消除丙型肝炎公共卫生威胁的重要基础，我国发布了《中国病毒性肝炎防治规划（2017-2020）》，期待通过有效的筛查、诊断和治疗，早日实现世界卫生组织消除病毒性肝炎公共卫生威胁的目标。.
Substance Nomenclature:: 0 (Antiviral Agents)
Entry Date(s):: Date Created: 20210309 Date Completed: 20210310 Latest Revision: 20210310
Update Code:: 20240105
DOI:: 10.3760/cma.j.cn501113-20210204-00066
PMID:: 33685075
: Czasopismo naukowe

Hepatitis C is the first chronic viral infection that can be cured, and it has taken only 30 years from the discovery of the hepatitis C virus genome to the ability to eliminate the public health threat posed by hepatitis C virus. In the past ten years, the etiological detection of hepatitis C has experienced the development from sensitive and quantitative to rapid, convenient, automatic and point of care testing. With the continuous introduction of direct antiviral drugs, all types of hepatitis C patients, including special populations, can be safely and effectively cured by short courses of all-oral drugs. Progress in the diagnosis and treatment of hepatitis C is an important basis for eliminating the public health threat of hepatitis C. China has published the Planning of prevent and treatment for viral hepatitis in China (2017-2020). We look forward to achieving WHO's goal of eliminating viral hepatitis as a public health threat at an early date through effective screening, diagnosis and treatment.

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