-
Tytuł:
-
Clinical significance of J waves with respect to substrate characteristics and ablation outcomes in patients with arrhythmogenic right ventricular cardiomyopathy.
-
Autorzy:
-
Lin CY; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Chung FP; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Lin YJ; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Chang SL; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Lo LW; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Hu YF; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Tuan TC; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Chao TF; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Liao JN; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Chang TY; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Kuo L; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Wu CI; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Liu CM; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Liu SH; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Cheng WH; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.
Lugtu IC; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.
Te ALD; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.
Huang TC; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.
Lee PT; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.
Vicera JJB; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.
Chen SA; Division of Cardiology, Department of Medicine, Heart Rhythm Center, Taipei Veterans General Hospital, No. 201, Section 2, Shih-Pai Road, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, School of Medicine, Taipei, Taiwan.; Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan.
-
Źródło:
-
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2021 Sep 08; Vol. 23 (9), pp. 1418-1427.
-
Typ publikacji:
-
Journal Article
-
Język:
-
English
-
Imprint Name(s):
-
Publication: 2006- : Oxford : Oxford University Press
Original Publication: London ; Philadelphia : Saunders, c1999-
-
MeSH Terms:
-
Arrhythmogenic Right Ventricular Dysplasia*/diagnosis
Arrhythmogenic Right Ventricular Dysplasia*/surgery
Catheter Ablation*
Tachycardia, Ventricular*/diagnosis
Tachycardia, Ventricular*/surgery
Endocardium/surgery ; Epicardial Mapping ; Humans ; Retrospective Studies
-
Contributed Indexing:
-
Keywords: Ablation; Arrhythmogenic right ventricular cardiomyopathy; Epicardial approach; J wave; Ventricular arrhythmia
-
Entry Date(s):
-
Date Created: 20210318 Date Completed: 20211020 Latest Revision: 20211020
-
Update Code:
-
20240105
-
DOI:
-
10.1093/europace/euab060
-
PMID:
-
33734367
-
Aims: J-wave syndrome in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) has been linked to an increased risk of ventricular arrhythmia. We investigated the significance of J waves with respect to substrate manifestations and ablation outcomes in patients with ARVC.
Methods and Results: Forty-five patients with ARVC undergoing endocardial/epicardial mapping/ablation were studied. Patients were classified into two groups: 13 (28.9%) and 32 (71.1%) patients with and without J waves, respectively. The baseline characteristics, electrophysiological features, ventricular substrate, and recurrent ventricular tachycardia/fibrillation (VT/VF) were compared. Among the 13 patients with J waves, only the inferior J wave was observed. More ARVC patients with J waves fulfilled the major criteria of ventricular arrhythmias (76.9% vs. 21.9%, P = 0.003). Similar endocardial and epicardial substrate characteristics were observed between the two groups. However, patients with J waves had longer epicardial total activation time than those without (224.7 ± 29.9 vs. 200.8 ± 21.9 ms, P = 0.005). Concordance of latest endo/epicardial activation sites was observed in 29 (90.6%) patients without J waves and in none among those with J waves (P < 0.001). Complete elimination of endocardial/epicardial abnormal potentials resulted in the disappearance of the J wave in 8 of 13 (61.5%) patients. The VT/VF recurrences were not different between ARVC patients with and without J waves.
Conclusion: The presence of J waves was associated with the discordance of endocardial/epicardial activation pattern in terms of transmural depolarization discrepancy in patients with ARVC.
(Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2021. For permissions, please email: journals.permissions@oup.com.)