Persistence of SARS-CoV-2 N-Antibody Response in Healthcare Workers, London, UK.

Szczegóły
Abstrakt

Tytuł:: Persistence of SARS-CoV-2 N-Antibody Response in Healthcare Workers, London, UK.
Autorzy:: Shrotri M
Harris RJ
Rodger A
Planche T
Sanderson F
Mahungu T
McGregor A
Heath PT
Brown CS
Dunning J
Hopkins S
Ladhani S
Chand M
Corporate Authors:: LondonCOVID Group
Źródło:: Emerging infectious diseases [Emerg Infect Dis] 2021 Apr; Vol. 27 (4), pp. 1155-1158. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
Język:: English
Imprint Name(s):: Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995-
MeSH Terms:: COVID-19*/diagnosis
COVID-19*/epidemiology
COVID-19*/immunology
COVID-19 Serological Testing*/methods
COVID-19 Serological Testing*/statistics & numerical data
Antibodies, Viral/*blood
Antibody Formation/*immunology
Coronavirus Nucleocapsid Proteins/*immunology
Health Personnel/*statistics & numerical data
Adult ; Female ; Humans ; London/epidemiology ; Male ; Phosphoproteins/immunology ; SARS-CoV-2/isolation & purification ; Seroconversion ; Seroepidemiologic Studies
References:: J Gen Virol. 2020 Aug;101(8):791-797. (PMID: 32430094)
Science. 2020 Dec 4;370(6521):1227-1230. (PMID: 33115920)
N Engl J Med. 2020 Oct 22;383(17):1694-1695. (PMID: 32966710)
J Clin Microbiol. 2020 May 26;58(6):. (PMID: 32229605)
N Engl J Med. 2020 Sep 10;383(11):1085-1087. (PMID: 32706954)
J Clin Invest. 2020 Oct 1;130(10):5235-5244. (PMID: 32634129)
Blood. 2020 Nov 26;136(22):2588-2591. (PMID: 33001206)
J Clin Virol. 2020 Sep;130:104575. (PMID: 32805631)
Nat Microbiol. 2020 Dec;5(12):1598-1607. (PMID: 33106674)
Lancet Infect Dis. 2020 Dec;20(12):1390-1400. (PMID: 32979318)
Contributed Indexing:: Keywords: COVID-19; London; SARS-CoV-2; antibodies; coronavirus disease; epidemiology; health personnel; healthcare workers; respiratory infections; serology; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses
Substance Nomenclature:: 0 (Antibodies, Viral)
0 (Coronavirus Nucleocapsid Proteins)
0 (Phosphoproteins)
0 (nucleocapsid phosphoprotein, SARS-CoV-2)
Entry Date(s):: Date Created: 20210318 Date Completed: 20210401 Latest Revision: 20210406
Update Code:: 20240105
PubMed Central ID:: PMC8007325
DOI:: 10.3201/eid2704.204554
PMID:: 33734962
: Czasopismo naukowe

Pełny tekst

Prospective serosurveillance of severe acute respiratory syndrome coronavirus 2 in 1,069 healthcare workers in London, UK, demonstrated that nucleocapsid antibody titers were stable and sustained for <12 weeks in 312 seropositive participants. This finding was consistent across demographic and clinical variables and contrasts with reports of short-term antibody waning.

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